Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome

BMC Biology

Volumn 13, Issue 1, 2015, Pages

  Venkatraman Girija, Umakhanth ^a   Furze, Christopher M ^a   Gingras, Alexandre R ^a,b   Yoshizaki, Takayuki ^c   Ohtani, Katsuki ^c   Marshall, Jamie E ^a   Wallis, A Katrine ^d   Schwaeble, Wilhelm J ^a   El Mezgueldi, Mohammed ^a   Mitchell, Daniel A ^e   Moody, Peter C E ^a   Wakamiya, Nobutaka ^c   Wallis, Russell ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

^d Institute for Clean Growth and Future Mobility   (United Kingdom)

^e UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NHS TRUST   (United Kingdom)

Author keywords

3MC syndrome; C type lectin; Complement activation; structural biology

Indexed keywords

MAMMALIA;

CALCIUM; CARBOHYDRATE; COLLECTIN; COLLECTIN CL-K1, HUMAN; DISACCHARIDE; GLYCOPROTEIN; LIGAND; MUTANT PROTEIN; PROTEIN BINDING;

ANIMAL; BOVINE; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL LINE; COMPLEMENT ACTIVATION; CRICETULUS; GENETICS; HAMSTER; HUMAN; KINETICS; METABOLISM; MULTIPLE MALFORMATION SYNDROME; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; RAT; SYNDROME; X RAY CRYSTALLOGRAPHY;

ABNORMALITIES, MULTIPLE; ANIMALS; CALCIUM; CARBOHYDRATES; CATTLE; CHO CELLS; COLLECTINS; COMPLEMENT ACTIVATION; CRICETINAE; CRICETULUS; CRYSTALLOGRAPHY, X-RAY; DISACCHARIDES; GLYCOPROTEINS; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; SYNDROME;

EID: 84938988207     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/s12915-015-0136-2     Document Type: Article

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