Oral Morphine Weaning for Neonatal Abstinence Syndrome at Home Compared with In-Hospital: An Observational Cohort Study

Pediatric Drugs

Volumn 17, Issue 2, 2014, Pages 151-157

  Kelly, Lauren E ^a   Knoppert, David ^c   Roukema, Henry ^c   Rieder, Michael J ^a,c   Koren, Gideon ^a,b,d  

^a WESTERN UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE;

CANADA; COHORT ANALYSIS; COMPARATIVE STUDY; HOSPITALIZATION; HUMAN; NEONATAL ABSTINENCE SYNDROME; NEWBORN; RETROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA;

COHORT STUDIES; HOSPITALIZATION; HUMANS; INFANT, NEWBORN; MORPHINE; NEONATAL ABSTINENCE SYNDROME; ONTARIO; RETROSPECTIVE STUDIES;

EID: 84938943281     PISSN: 11745878     EISSN: 11792019     Source Type: Journal    
DOI: 10.1007/s40272-014-0096-y     Document Type: Article

References (19)

1. Women ACoHCfU, American Society of Addiction M. ACOG Committee Opinion No. 524: opioid abuse, dependence, and addiction in pregnancy. Obstet Gynecol. 2012;119(5):1070–6.
2. Services USDoHaH. National Survey on Drug Use and Health: Summary of National Findings. 2010; Available from http://oas.samhsa.gov/NSDUH/2k10NSDUH/2k10Results.htm.
3. Pinto SM, Dodd S, Walkinshaw SA, Siney C, Kakkar P, Mousa HA. Substance abuse during pregnancy: effect on pregnancy outcomes. Eur J Obstet Gynecol Reprod Biol. 2010;150(2):137–41.
4. Seligman NS, Salva N, Hayes EJ, Dysart KC, Pequignot EC, Baxter JK. Predicting length of treatment for neonatal abstinence syndrome in methadone-exposed neonates. Am J Obstet Gynecol. 2008;199(4):396 e1–7.
5. Bateman BT, Hernandez-Diaz S, Rathmell JP, Seeger JD, Doherty M, Fischer MA, et al. Patterns of opioid utilization in pregnancy in a large cohort of commercial insurance beneficiaries in the United States. Anesthesiology. 2014;120(5):1216–24.
6. de Castro A, Jones HE, Johnson RE, Gray TR, Shakleya DM, Huestis MA. Maternal methadone dose, placental methadone concentrations, and neonatal outcomes. Clin Chem. 2011;57(3):449–58.
7. Little BB, VanBeveren TT. Placental transfer of selected substances of abuse. Semin Perinatol. 1996;20(2):147–53.
8. Jansson LM, Di Pietro JA, Elko A, Williams EL, Milio L, Velez M. Pregnancies exposed to methadone, methadone and other illicit substances, and poly-drugs without methadone: a comparison of fetal neurobehaviors and infant outcomes. Drug Alcohol Depend. 2012;122(3):213–9.
9. O’Grady MJ, Hopewell J, White MJ. Management of neonatal abstinence syndrome: a national survey and review of practice. Arch Dis Child Fetal Neonatal Edition. 2009;94(4):F249–52.
10. Sarkar S, Donn SM. Management of neonatal abstinence syndrome in neonatal intensive care units: a national survey. J Perinatol Off J Calif Perinat Assoc. 2006;26(1):15–7.
11. Agthe AG, Kim GR, Mathias KB, Hendrix CW, Chavez-Valdez R, Jansson L, et al. Clonidine as an adjunct therapy to opioids for neonatal abstinence syndrome: a randomized, controlled trial. Pediatrics. 2009;123(5):e849–56.
12. Finnegan LP, Connaughton JF Jr, Kron RE, Emich JP. Neonatal abstinence syndrome: assessment and management. Addict Dis. 1975;2(1–2):141–58.
13. Kelly JJ, Davis PG, Henschke PN. The drug epidemic: effects on newborn infants and health resource consumption at a tertiary perinatal centre. J Paediatr Child Health. 2000;36(3):262–4.
14. Patrick SW, Schumacher RE, Benneyworth BD, Krans EE, McAllister JM, Davis MM. Neonatal abstinence syndrome and associated health care expenditures: United states, 2000–2009. JAMA. 2012;307(18):1934–40.
15. Backes CH, Backes CR, Gardner D, Nankervis CA, Giannone PJ, Cordero L. Neonatal abstinence syndrome: transitioning methadone-treated infants from an inpatient to an outpatient setting. J Perinatol Off J Calif Perinatal Assoc. 2012;32(6):425–30.
16. Liu A, Bjorkman T, Stewart C, Nanan R. Pharmacological treatment of neonatal opiate withdrawal: between the devil and the deep blue sea. Int J Pediatr. 2011;2011:935631.
17. Kelly LE, Rieder MJ, Bridgman-Acker K, Lauwers A, Madadi P, Koren G. Are infants exposed to methadone in utero at an increased risk for mortality? J Popul Therap Clin Pharmacol. 2012;19(2):e160–5.
18. Fulroth R, Phillips B, Durand DJ. Perinatal outcome of infants exposed to cocaine and/or heroin in utero. Am J Dis Child. 1989;143(8):905–10.
19. Pritham UA. Breastfeeding promotion for management of neonatal abstinence syndrome. JOGNN/NAACOG. 2013;42(5):517–26.