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Volumn 58, Issue 15, 2015, Pages 5691-5698

Volume of Distribution in Drug Design

Author keywords

[No Author keywords available]

Indexed keywords

SMALL MOLECULE TRANSPORT AGENT;

EID: 84938919255     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00201     Document Type: Article
Times cited : (187)

References (32)
  • 1
    • 0020613566 scopus 로고
    • Significance of ratios of different volumes of distribution in pharmacokinetics
    • Wagner, J. G. Significance of ratios of different volumes of distribution in pharmacokinetics Biopharm. Drug Dispos. 1983, 4, 263-270
    • (1983) Biopharm. Drug Dispos. , vol.4 , pp. 263-270
    • Wagner, J.G.1
  • 2
    • 0015212973 scopus 로고
    • Factors affecting drug metabolism
    • Gillette, J. R. Factors affecting drug metabolism Ann. N.Y. Acad. Sci. 1971, 179, 43-66
    • (1971) Ann. N.Y. Acad. Sci. , vol.179 , pp. 43-66
    • Gillette, J.R.1
  • 3
    • 0018668570 scopus 로고
    • Effect of altered plasma protein binding on apparent volume of distribution
    • Øie, S.; Tozer, T. N. Effect of altered plasma protein binding on apparent volume of distribution J. Pharm. Sci. 1979, 68, 1203-1205
    • (1979) J. Pharm. Sci. , vol.68 , pp. 1203-1205
    • Øie, S.1    Tozer, T.N.2
  • 6
    • 34247556082 scopus 로고    scopus 로고
    • Mechanistic approaches to volume of distribution predictions: Understanding the processes
    • Rodgers, T.; Rowland, M. Mechanistic approaches to volume of distribution predictions: understanding the processes Pharm. Res. 2007, 24, 918-933
    • (2007) Pharm. Res. , vol.24 , pp. 918-933
    • Rodgers, T.1    Rowland, M.2
  • 7
    • 79951886926 scopus 로고    scopus 로고
    • Role of phosphatidylserine binding in tissue distribution of amine-containing basic compounds
    • Murakami, T.; Yumoto, R. Role of phosphatidylserine binding in tissue distribution of amine-containing basic compounds Expert Opin. Drug Metab. Toxicol. 2011, 7, 353-364
    • (2011) Expert Opin. Drug Metab. Toxicol. , vol.7 , pp. 353-364
    • Murakami, T.1    Yumoto, R.2
  • 8
    • 0024993409 scopus 로고
    • Phosphatidylserine as a determinant for the tissue distribution of weakly basic drugs in rats
    • Yata, N.; Toyoda, T.; Murakami, T.; Nishiura, A.; Higashi, Y. Phosphatidylserine as a determinant for the tissue distribution of weakly basic drugs in rats Pharm. Res. 1990, 7, 1019-1025
    • (1990) Pharm. Res. , vol.7 , pp. 1019-1025
    • Yata, N.1    Toyoda, T.2    Murakami, T.3    Nishiura, A.4    Higashi, Y.5
  • 9
    • 84888221904 scopus 로고    scopus 로고
    • Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation
    • Ghosh, A.; Scott, D. O.; Maurer, T. S. Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation Eur. J. Pharm. Sci. 2014, 52, 109-124
    • (2014) Eur. J. Pharm. Sci. , vol.52 , pp. 109-124
    • Ghosh, A.1    Scott, D.O.2    Maurer, T.S.3
  • 10
    • 11144290156 scopus 로고    scopus 로고
    • Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice
    • Maurer, T. S.; DeBartolo, D. B.; Tess, D. A.; Scott, D. O. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice Drug Metab. Dispos. 2005, 33, 175-181
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 175-181
    • Maurer, T.S.1    Debartolo, D.B.2    Tess, D.A.3    Scott, D.O.4
  • 11
    • 0023026272 scopus 로고
    • The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily
    • Faulkner, J. K.; McGibney, D.; Chasseaud, L. F.; Perry, J. L.; Taylor, I. W. The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily Br. J. Clin. Pharmacol. 1986, 22, 21-25
    • (1986) Br. J. Clin. Pharmacol. , vol.22 , pp. 21-25
    • Faulkner, J.K.1    McGibney, D.2    Chasseaud, L.F.3    Perry, J.L.4    Taylor, I.W.5
  • 12
    • 0023788089 scopus 로고
    • Pharmacokinetics of calcium antagonists under development
    • Abernethy, D. R.; Schwartz, J. B. Pharmacokinetics of calcium antagonists under development Clin. Pharmacokinet. 1988, 15, 1-14
    • (1988) Clin. Pharmacokinet. , vol.15 , pp. 1-14
    • Abernethy, D.R.1    Schwartz, J.B.2
  • 13
    • 0022634910 scopus 로고
    • Aspects of the clinical pharmacology of nifedipine, a dihydropyridine calcium-entry antagonist
    • Hamann, S. R.; Piascik, M. T.; McAllister, R. G., Jr. Aspects of the clinical pharmacology of nifedipine, a dihydropyridine calcium-entry antagonist Biopharm. Drug Dispos. 1986, 7, 1-10
    • (1986) Biopharm. Drug Dispos. , vol.7 , pp. 1-10
    • Hamann, S.R.1    Piascik, M.T.2    McAllister, R.G.3
  • 14
    • 0018188451 scopus 로고
    • Pharmacokinetics of intravenous erythromycin
    • Welling, P. G.; Craig, W. A. Pharmacokinetics of intravenous erythromycin J. Pharm. Sci. 1978, 67, 1057-1059
    • (1978) J. Pharm. Sci. , vol.67 , pp. 1057-1059
    • Welling, P.G.1    Craig, W.A.2
  • 15
    • 0029911053 scopus 로고    scopus 로고
    • Safety, toleration, and pharmacokinetics of intravenous azithromycin
    • Luke, D. R.; Foulds, G.; Cohen, S. F.; Levy, B. Safety, toleration, and pharmacokinetics of intravenous azithromycin Antimicrob. Agents Chemother. 1996, 40, 2577-2581
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2577-2581
    • Luke, D.R.1    Foulds, G.2    Cohen, S.F.3    Levy, B.4
  • 16
    • 0025096817 scopus 로고
    • The pharmacokinetics of azithromycin in human serum and tissues
    • Foulds, G.; Shepard, R. M.; Johnson, R. B. The pharmacokinetics of azithromycin in human serum and tissues J. Antimicrob. Chemother. 1990, 25, 73-82
    • (1990) J. Antimicrob. Chemother. , vol.25 , pp. 73-82
    • Foulds, G.1    Shepard, R.M.2    Johnson, R.B.3
  • 17
    • 70349083023 scopus 로고    scopus 로고
    • Modulation of the partition coefficient between octanol and buffer at pH 7.4 and pKa to achieve the optimum balance of blood clearance and volume of distribution for a series of tetrahydropyran histamine type 3 receptor antagonists
    • Hay, T.; Jones, R.; Beaumont, K.; Kemp, M. Modulation of the partition coefficient between octanol and buffer at pH 7.4 and pKa to achieve the optimum balance of blood clearance and volume of distribution for a series of tetrahydropyran histamine type 3 receptor antagonists Drug Metab. Dispos. 2009, 37, 1864-1870
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 1864-1870
    • Hay, T.1    Jones, R.2    Beaumont, K.3    Kemp, M.4
  • 18
    • 0023187286 scopus 로고
    • Synthesis of a series of compounds related to betaxolol, a new β1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases
    • Manoury, P. M.; Binet, J. L.; Rousseau, J.; Lefevre-Borg, F. M.; Cavero, I. G. Synthesis of a series of compounds related to betaxolol, a new β1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases J. Med. Chem. 1987, 30, 1003-1011
    • (1987) J. Med. Chem. , vol.30 , pp. 1003-1011
    • Manoury, P.M.1    Binet, J.L.2    Rousseau, J.3    Lefevre-Borg, F.M.4    Cavero, I.G.5
  • 19
    • 0023872441 scopus 로고
    • Distribution coefficient, a convenient term for the relation of predictable physicochemical properties to metabolic processes
    • Manners, C. N.; Payling, D. W.; Smith, D. A. Distribution coefficient, a convenient term for the relation of predictable physicochemical properties to metabolic processes Xenobiotica 1988, 18, 331-350
    • (1988) Xenobiotica , vol.18 , pp. 331-350
    • Manners, C.N.1    Payling, D.W.2    Smith, D.A.3
  • 20
    • 84890646014 scopus 로고    scopus 로고
    • Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: Case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein
    • Higgins, J. W.; Bao, J. Q.; Ke, A. B.; Manro, J. R.; Fallon, J. K.; Smith, P. C.; Zamek-Gliszczynski, M. J. Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein Drug Metab. Dispos. 2014, 42, 182-192
    • (2014) Drug Metab. Dispos. , vol.42 , pp. 182-192
    • Higgins, J.W.1    Bao, J.Q.2    Ke, A.B.3    Manro, J.R.4    Fallon, J.K.5    Smith, P.C.6    Zamek-Gliszczynski, M.J.7
  • 22
    • 68149151186 scopus 로고    scopus 로고
    • Effects of drug transporters on volume of distribution
    • Grover, A.; Benet, L. Z. Effects of drug transporters on volume of distribution AAPS J. 2009, 11, 250-261
    • (2009) AAPS J. , vol.11 , pp. 250-261
    • Grover, A.1    Benet, L.Z.2
  • 23
    • 0036349377 scopus 로고    scopus 로고
    • Enterohepatic circulation: Physiological, pharmacokinetic and clinical implications
    • Roberts, M. S.; Magnusson, B. M.; Burczynski, F. J.; Weiss, M. Enterohepatic circulation: physiological, pharmacokinetic and clinical implications Clin. Pharmacokinet. 2002, 41, 751-790
    • (2002) Clin. Pharmacokinet. , vol.41 , pp. 751-790
    • Roberts, M.S.1    Magnusson, B.M.2    Burczynski, F.J.3    Weiss, M.4
  • 25
    • 84939133414 scopus 로고    scopus 로고
    • Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats
    • Deng, J.; Zhuang, X.; Shen, G.; Li, H.; Gong, Z. Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats Acta Pharm. Sin. B 2012, 2, 174-180
    • (2012) Acta Pharm. Sin. B , vol.2 , pp. 174-180
    • Deng, J.1    Zhuang, X.2    Shen, G.3    Li, H.4    Gong, Z.5
  • 26
    • 0025324933 scopus 로고
    • Indirect assessment of the enterohepatic recirculation of piroxicam and tenoxicam
    • Benveniste, C.; Striberni, R.; Dayer, P. Indirect assessment of the enterohepatic recirculation of piroxicam and tenoxicam Eur. J. Clin. Pharmacol. 1990, 38, 547-549
    • (1990) Eur. J. Clin. Pharmacol. , vol.38 , pp. 547-549
    • Benveniste, C.1    Striberni, R.2    Dayer, P.3
  • 27
    • 67650729799 scopus 로고    scopus 로고
    • Target-mediated drug disposition model: Approximations, identifiability of model parameters and applications to the population pharmacokinetic-pharmacodynamic modeling of biologics
    • Gibiansky, L.; Gibiansky, E. Target-mediated drug disposition model: approximations, identifiability of model parameters and applications to the population pharmacokinetic-pharmacodynamic modeling of biologics Expert Opin. Drug Metab. Toxicol. 2009, 5, 803-812
    • (2009) Expert Opin. Drug Metab. Toxicol. , vol.5 , pp. 803-812
    • Gibiansky, L.1    Gibiansky, E.2
  • 28
    • 84878215338 scopus 로고    scopus 로고
    • Application of target-mediated drug disposition model to small molecule heat shock protein 90 inhibitors
    • Yamazaki, S.; Shen, Z.; Jiang, Y.; Smith, B. J.; Vicini, P. Application of target-mediated drug disposition model to small molecule heat shock protein 90 inhibitors Drug Metab. Dispos. 2013, 41, 1285-1294
    • (2013) Drug Metab. Dispos. , vol.41 , pp. 1285-1294
    • Yamazaki, S.1    Shen, Z.2    Jiang, Y.3    Smith, B.J.4    Vicini, P.5
  • 29
    • 46449114275 scopus 로고    scopus 로고
    • Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds
    • Obach, R. S.; Lombardo, F.; Waters, N. J. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds Drug Metab. Dispos. 2008, 36, 1385-1405
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1385-1405
    • Obach, R.S.1    Lombardo, F.2    Waters, N.J.3


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