Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer models

Biomatter

Volumn 4, Issue , 2014, Pages e955386-

  Ricci, Claudio ^a   Mota, Carlos ^a   Moscato, Stefania ^a   D'Alessandro, Delfo ^a   Ugel, Stefano ^a   Sartoris, Silvia ^a   Bronte, Vincenzo ^a   Boggi, Ugo ^a   Campani, Daniela ^a   Funel, Niccola ^a   Moroni, Lorenzo ^a   Danti, Serena ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

2D, Bi dimensional; 3D, Three dimensional; BCA, Bicinchoninic acid; BSA, Bovine serum albumin; cancer; compression molding; Dd, double distilled; Ds, double stranded; ECM, Extracellular matrix; electrospinning; emulsion and freeze drying; G, Gelatin; HRP, Horseradish peroxidase; K ras, Kirsten rat sarcoma viral oncogene homolog; metalloproteinase 2 (MMP 2); metalloproteinase 9 (MMP 9); MMP, Matrix metalloproteinase; Pancreatic adenocarcinoma; PanIN, Pancreatic intraepithelial neoplasia; PBS, Phosphate buffer saline; PCR, Polymer chain reaction; PDAC, Pancreatic ductal adenocarcinoma; PEOT PBT, Poly(ethylene oxide terephthalate) poly(butylene terephthalate); polyethylene oxide terephthalate (PEOT); polyvinyl alcohol (PVA); PVA, Poly(vinyl alcohol); scaffold; Smad4, Mothers against decapentaplegic homolog 4; TME, Tumor microenvironment.

Indexed keywords

BIOMATERIAL; METALLOPROTEINASE; POLYESTER; POLYETHYLENE TEREPHTHALATE;

BIOLOGICAL MODEL; CELL CULTURE; CELL PROLIFERATION; CULTURE TECHNIQUE; DRUG EFFECTS; HUMAN; METABOLISM; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PROCEDURES; TISSUE ENGINEERING; TISSUE SCAFFOLD;

BIOCOMPATIBLE MATERIALS; CARCINOMA, PANCREATIC DUCTAL; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; METALLOPROTEASES; MODELS, BIOLOGICAL; PANCREATIC NEOPLASMS; POLYESTERS; POLYETHYLENE TEREPHTHALATES; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84938856330     PISSN: None     EISSN: 21592535     Source Type: Journal    
DOI: 10.4161/21592527.2014.955386     Document Type: Article

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