Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips

BMC Biotechnology

Volumn 15, Issue 1, 2015, Pages

  Valentina, Manfè ^a,b   Jan, Fleckner ^a   Peder, Nørby Lisby ^a   Bo, Zhang ^b   Hongjie, Dai ^b   Pernille, Keller ^a  

^a NOVO NORDISK A S   (Denmark)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Cytokines; Fluorescence enhancement; IL 20; Osteoarthritis; Plasmonic gold; Protein microarray; Rheumatoid arthritis; Rheumatoid factor interference

Indexed keywords

ANTIBODIES; BIOASSAY; BIOCHIPS; DISEASES; FLUORESCENCE; GOLD; INFRARED DEVICES; MICROARRAYS; PLASMONS; PROTEINS;

CYTOKINES; FLUORESCENCE ENHANCEMENT; IL-20; OSTEOARTHRITIS; PROTEIN MICROARRAY; RHEUMATOID ARTHRITIS; RHEUMATOID FACTORS;

BODY FLUIDS;

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 20; INTERLEUKIN 6; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR ALPHA; GOLD; INTERLEUKIN DERIVATIVE;

ADULT; ANALYTICAL EQUIPMENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; OSTEOARTHRITIS; PLASMONIC GOLD CHIP; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PROCESSING; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID LEVEL; ANIMAL; BLOOD; CHEMISTRY; IMMUNOASSAY; IMMUNOLOGY; SYNOVIAL FLUID;

ANIMALIA;

ANIMALS; ARTHRITIS, RHEUMATOID; FEMALE; GOLD; HUMANS; IMMUNOASSAY; INTERLEUKINS; MALE; OSTEOARTHRITIS; PROTEIN ARRAY ANALYSIS; RHEUMATOID FACTOR; SYNOVIAL FLUID;

EID: 84938820453     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/s12896-015-0186-0     Document Type: Article

References (24)

1. Feldmann M. Many cytokines are very useful therapeutic targets in disease. J Clin Invest. 2008;118:3533-6.
2. Cox KL, Devanarayan V, Kriauciunas A, Manetta J, Montrose C, Sittampalam S: Immunoassay Methods. 2004.
3. Selvarajah S, Negm OH, Hamed MR, Tubby C, Todd I, Tighe PJ, et al. Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators Inflamm. 2014;2014:820304.
4. Tabakman SM, Lau L, Robinson JT, Price J, Sherlock SP, Wang H, et al. Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range. Nat Commun. 2011;2:466.
5. Zhang B, Jarrell JA, Price JV, Tabakman SM, Li Y, Gong M, et al. An integrated peptide-antigen microarray on plasmonic gold films for sensitive human antibody profiling. PLoS One. 2013;8:e71043.
6. Zhang B, Kumar RB, Dai H, Feldman BJ. A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes. Nat Med. 2014;20:948-53.
7. Zhang B, Price J, Hong G, Tabakman SM, Wang H, Jarrell JA, Hong G, Utz PJ, Dai H. Multiplexed cytokine detection on plasmonic gold substrates with enhanced near-infrared fluorescence. Nano Research 2013.
8. Leng RX, Pan HF, Tao JH, Ye DQ. IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases. Expert Opin Ther Targets. 2011;15:119-26.
9. Otkjaer K, Kragballe K, Funding AT, Clausen JT, Noerby PL, Steiniche T, et al. The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis. Br J Dermatol. 2005;153:911-8.
10. Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, et al. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis Rheum. 2006;54:2722-33.
11. Hsing CH, Cheng HC, Hsu YH, Chan CH, Yeh CH, Li CF, et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res. 2012;18:713-25.
12. Wei CC, Hsu YH, Li HH, Wang YC, Hsieh MY, Chen WY, et al. IL-20: biological functions and clinical implications. J Biomed Sci. 2006;13:601-12.
13. Lee SJ, Cho SC, Lee EJ, Kim S, Lee SB, Lim JH, et al. Interleukin-20 promotes migration of bladder cancer cells through extracellular signal-regulated kinase (ERK)-mediated MMP-9 protein expression leading to nuclear factor (NF-kappaB) activation by inducing the up-regulation of p21(WAF1) protein expression. J Biol Chem. 2013;288:5539-52.
14. Aydogdu E, Pamuk ON, Donmez S, Pamuk GE. Decreased interleukin-20 level in patients with systemic sclerosis: are they related with angiogenesis? Clin Rheumatol. 2013;32:1599-603.
15. Kragstrup TW, Otkjaer K, Holm C, Jorgensen A, Hokland M, Iversen L, et al. The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine. 2008;41:16-23.
16. Todd DJ, Knowlton N, Amato M, Frank MB, Schur PH, Izmailova ES, et al. Erroneous augmentation of multiplex assay measurements in patients with rheumatoid arthritis due to heterophilic binding by serum rheumatoid factor. Arthritis Rheum. 2011;63:894-903.
17. Gonzalez A, Icen M, Kremers HM, Crowson CS, Davis III JM, Therneau TM, et al. Mortality trends in rheumatoid arthritis: the role of rheumatoid factor. J Rheumatol. 2008;35:1009-14.
18. Moore TL, Dorner RW. Rheumatoid factors. Clin Biochem. 1993;26:75-84.
19. Ward G, McKinnon L, Badrick T, Hickman PE. Heterophilic antibodies remain a problem for the immunoassay laboratory. Am J Clin Pathol. 1997;108:417-21.
20. Kragstrup TW, Vorup-Jensen T, Deleuran B, Hvid M. A simple set of validation steps identifies and removes false results in a sandwich enzyme-linked immunosorbent assay caused by anti-animal IgG antibodies in plasma from arthritis patients. Springerplus. 2013;2:263.
21. Tate J, Ward G. Interferences in immunoassay. Clin Biochem Rev. 2004;25:105-20.
22. Scrivo R, Conigliaro P, Riccieri V, Di FM, Alessandri C, Spadaro A, et al. Distribution of IL-10 family cytokines in serum and synovial fluid of patients with inflammatory arthritis reveals different contribution to systemic and joint inflammation. Clin Exp Immunol. 2015;179(2):300-8.
23. Sturgeon CM, Viljoen A. Analytical error and interference in immunoassay: minimizing risk. Ann Clin Biochem. 2011;48:418-32.
24. Tiwari G, Tiwari R. Bioanalytical method validation: An updated review. Pharm Methods. 2010;1:25-38.