Effects of age, but not sex, on elevated startle during withdrawal from acute morphine in adolescent and adult rats

Behavioural Pharmacology

Volumn 26, Issue 5, 2015, Pages 485-488

  Radke, Anna K ^a,b   Gewirtz, Jonathan C ^a   Carroll, Marilyn E ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

adolescent; adult; morphine; rat; startle; withdrawal

Indexed keywords

ALCOHOL; MORPHINE SULFATE; OPIATE; MORPHINE; NARCOTIC AGENT;

ACOUSTIC REFLEX; ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EMOTION; FEMALE; MALE; NONHUMAN; RAT; SEX DIFFERENCE; STARTLE REFLEX; WITHDRAWAL SYNDROME; AGING; ANALYSIS OF VARIANCE; ANIMAL; AUDITORY STIMULATION; DRUG EFFECTS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY; SEXUAL DEVELOPMENT; SPRAGUE DAWLEY RAT; TIME FACTOR;

ACOUSTIC STIMULATION; AGING; ANALYSIS OF VARIANCE; ANIMALS; FEMALE; MALE; MORPHINE; NARCOTICS; RATS, SPRAGUE-DAWLEY; REFLEX, STARTLE; SEX CHARACTERISTICS; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS;

EID: 84938815529     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0000000000000151     Document Type: Article

References (41)

1. Badanich KA, Adler KJ, Kirstein CL (2006). Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi. Eur J Pharmacol 550:95-106.
2. Brasser SM, Spear NE (2002). Physiological and behavioral effects of acute ethanol hangover in juvenile, adolescent, and adult rats. Behav Neurosci 116:305-320.
3. Brenhouse HC, Andersen SL (2008). Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults. Behav Neurosci 122:460-465.
4. Brenhouse HC, Sonntag KC, Andersen SL (2008). Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence. J Neurosci 28:2375-2382.
5. Brielmaier JM, McDonald CG, Smith RF (2007). Immediate and long-term behavioral effects of a single nicotine injection in adolescent and adult rats. Neurotoxicol Teratol 29:74-80.
6. Carroll ME, Mach JL, La Nasa RM, Newman JL (2009). Impulsivity as a behavioral measure of withdrawal of orally delivered PCP and nondrug rewards in male and female monkeys. Psychopharmacology (Berl) 207:85-98.
7. Carroll ME, Anker JJ, Perry JL (2009). Modeling risk factors for nicotine and other drugs of abuse in the preclinical laboratory. Drug and Alcohol Dependence 104S:S70-S78.
8. Chen H, Matta SG, Sharp BM (2007). Acquisition of nicotine self-administration in adolescent rats given prolonged access to the drug. Neuropsychopharmacology 32:700-709.
9. Cicero TJ, Nock B, Meyer ER (2002). Gender-linked differences in the expression of physical dependence in the rat. Pharmacol Biochem Behav 72:691-697.
10. Craft RM, Stratmann JA, Bartok RE, Walpole TI, King SJ (1999). Sex differences in development of morphine tolerance and dependence in the rat. Psychopharmacology (Berl) 143:1-7.
11. Doremus TL, Brunell SC, Varlinskaya EI, Spear LP (2003). Anxiogenic effects during withdrawal from acute ethanol in adolescent and adult rats. Pharmacol Biochem Behav 75:411-418.
12. Doremus-Fitzwater TL, Spear LP (2007). Developmental differences in acute ethanol withdrawal in adolescent and adult rats. Alcohol Clin Exp Res 31:1516-1527.
13. Engelmann JM, Radke AK, Gewirtz JC (2009). Potentiated startle as a measure of the negative affective consequences of repeated exposure to nicotine in rats. Psychopharmacology (Berl) 207:13-25.
14. Füllgrabe MW, Vengeliene V, Spanagel R (2007). Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats. Pharmacol Biochem Behav 86:320-326.
15. Gatch MB, Lal H (2001). Animal models of the anxiogenic effects of ethanol withdrawal. Drug Dev Res 54:95-115.
16. Harris AC, Gewirtz JC (2004). Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety. Psychopharmacology (Berl) 171:140-147.
17. Hodgson SR, Hofford RS, Wellman PJ, Eitan S (2009). Different affective response to opioid withdrawal in adolescent and adult mice. Life Sci 84:52-60.
18. Holtz NA, Radke AK, Zlebnik NE, Harris AC, Carroll ME (2015). Intracranial selfstimulation reward thresholds during morphine withdrawal in rats bred for high (HiS) and low (LoS) saccharin intake. Brain Research 1602:199-126.
19. Institute for Laboratory Animal Research (2011). Guide for the care and use of laboratory animals, 8th edition. Washington, DC: National Academies Press.
20. Jøhannesson T, Becker BA (1973). Morphine analgesia in rats at various ages. Acta Pharmacol Toxicol (Copenh) 33:429-441.
21. Kest B, Palmese CA, Hopkins E, Adler M, Juni A (2001). Assessment of acute and chronic morphine dependence in male and female mice. Pharmacol Biochem Behav 70:149-156.
22. Kota D, Martin BR, Robinson SE, Damaj MI (2007). Nicotine dependence and reward differ between adolescent and adult male mice. J Pharmacol Exp Ther 322:399-407.
23. Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, et al. (2004). Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews 27:739-749.
24. Levin ED, Rezvani AH, Montoya D, Rose JE, Swartzwelder HS (2003). Adolescent-onset nicotine self-administration modeled in female rats. Psychopharmacology (Berl) 169:141-149.
25. Levin ED, Lawrence SS, Petro A, Horton K, Rezvani AH, Seidler FJ, Slotkin TA (2007). Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates. Neurotoxicol Teratol 29:458-465.
26. O'Dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, et al. (2006). Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology (Berl) 186:612-619.
27. O'Dell LE, Torres OV, Natividad LA, Tejeda HA (2007). Adolescent nicotine exposure produces less affective measures of withdrawal relative to adult nicotine exposure in male rats. Neurotoxicol Teratol 29:17-22.
28. Perry JL, Normile LM, Morgan AD, Carroll ME (2006). Sex differences in physical dependence on orally self-administered phencyclidine (PCP) in rhesus monkeys (Macaca mulatta). Exp Clin Psychopharmacol 14:68-78.
29. Radke AK, Rothwell PE, Gewirtz JC (2011). An anatomical basis for opponent process mechanisms of opiate withdrawal. J Neurosci 31:7533-7539.
30. Radke AK, Holtz NA, Gewirtz JC, Carroll ME (2013). Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Psychopharmacology (Berl) 227:117-126.
31. Radke AK, Zlebnik NE, Carroll ME (2015). Cocaine withdrawal in rats selectively bred for low (LoS) or high (HiS) saccharin intake. Pharmacology, Biochemistry, and Behavior 129:51-55.
32. Rassnick S, Koob GF, Geyer MA (1992). Responding to acoustic startle during chronic ethanol intoxication and withdrawal. Psychopharmacology (Berl) 106:351-358.
33. Rothwell PE, Thomas MJ, Gewirtz JC (2009). Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure. Neuropsychopharmacology 34:2285-2295.
34. Shahbazi M, Moffett AM, Williams BF, Frantz KJ (2008). Age-and sex-dependent amphetamine self-administration in rats. Psychopharmacology (Berl) 196:71-81.
35. Shram MJ, Funk D, Li Z, Lê AD (2006). Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine. Psychopharmacology (Berl) 186:201-208.
36. Torres OV, Tejeda HA, Natividad LA, O'Dell LE (2008). Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development. Pharmacol Biochem Behav 90:658-663.
37. Vetter CS, Doremus-Fitzwater TL, Spear LP (2007). Time course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntaryaccess conditions. Alcohol Clin Exp Res 31:1159-1168.
38. Walker DL, Davis M (2002). Quantifying fear potentiated startle using absolute versus proportional increase scoring methods: implications for the neurocircuitry of fear and anxiety. Psychopharmacology (Berl) 164:318-328.
39. White DA, Michaels CC, Holtzman SG (2008). Periadolescent male but not female rats have higher motor activity in response to morphine than do adult rats. Pharmacol Biochem Behav 89:188-199.
40. Zakharova E, Leoni G, Kichko I, Izenwasser S (2009a). Differential effects of methamphetamine and cocaine on conditioned place preference and locomotor activity in adult and adolescent male rats. Behav Brain Res 198:45-50.
41. Zakharova E, Wade D, Izenwasser S (2009b). Sensitivity to cocaine conditioned reward depends on sex and age. Pharmacol Biochem Behav 92:131-134.