Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor α and β chains using next-generation sequencing (NGS)

OncoImmunology

Volumn 3, Issue 12, 2014, Pages 1-12

  Fang, Hua ^a,b   Yamaguchi, Rui ^c   Liu, Xiao ^b   Daigo, Yataro ^d   Yew, Poh Yin ^b   Tanikawa, Chizu ^c   Matsuda, Koichi ^c   Imoto, Seiya ^c   Miyano, Satoru ^c   Nakamura, Yusuke ^a,b,e,f  

^a UNIVERSITY OF CHICAGO   (United States)

^b SECTION OF HEMATOLOGY ONCOLOGY   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d SHIGA UNIVERSITY OF MEDICAL SCIENCE HOSPITAL   (Japan)

^e THE UNIVERSITY OF CHICAGO   (United States)

^f University of Chicago   (United States)

Author keywords

cancer peptide vaccines; complementary determining region 3; immune responses; next generation sequencing; T cell repertoire

Indexed keywords

CANCER VACCINE; CD45 ANTIGEN; CELL DIVISION CYCLE ASSOCIATED PROTEIN 1; COMPLEMENTARY DNA; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; KINESIN FAMILY MEMBER 20A; LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS K; PEPTIDE VACCINE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ALLERGY; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNE DISEASE; CARCINOMA; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; COMPLEMENTARITY DETERMINING REGION; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSPOT ASSAY; GENE MAPPING; GENETIC ALGORITHM; HUMAN; IMMUNE RESPONSE; LUNG CANCER; MALE; MITOTIC RECOMBINATION; NEXT GENERATION SEQUENCING; NON SMALL CELL LUNG CANCER; ORGAN TRANSPLANTATION; OVERALL SURVIVAL; PERIPHERAL LYMPHOCYTE; PHASE 1 CLINICAL TRIAL; POLYMERASE CHAIN REACTION; PROGRESSION FREE SURVIVAL; QUANTITATIVE ANALYSIS; RNA SPLICING; SERIAL ANALYSIS OF GENE EXPRESSION; SQUAMOUS CELL CARCINOMA; T LYMPHOCYTE; VDJ EXON;

EID: 84938793194     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/21624011.2014.968467     Document Type: Article

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