Evaluation of Acoustic Membrane Microparticle (AMMP) Technology for a Sensitive Ligand Binding Assay to Support Pharmacokinetic Determinations of a Biotherapeutic

Botanical Review

Volumn 16, Issue 6, 2014, Pages 1366-1371

  Chilewski, Shannon D ^a   Dickerson, W Matthew ^b   Mora, Johanna R ^a   Saab, Ashley ^b   Alderman, Edward M ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b BioScale Inc   (United States)

Author keywords

acoustic membrane microparticle technology; biotherapeutics; emerging technology; ligand binding assays; pharmacokinetics

Indexed keywords

BIOLOGICAL MARKER; LIGAND; MONOCLONAL ANTIBODY; ANTIBODY; FLUORESCEIN; PEGYLATED DOMAIN ANTIBODY; UNCLASSIFIED DRUG;

BIOLOGICAL MODEL; BLOOD; DEVICES; GENETIC PROCEDURES; HUMAN; IMMUNOASSAY; LIMIT OF DETECTION; MAGNETISM; PROCEDURES; REPRODUCIBILITY; ACCURACY; ACOUSTIC MEMBRANE MICROPARTICLE TECHNOLOGY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BIOLOGICAL THERAPY; BIOTECHNOLOGY; CHEMOLUMINESCENCE; COMPETITION ASSAY; CROSS SITE TESTING; DILUTIONAL LINEARITY; DRUG SELECTIVITY; LIMIT OF QUANTITATION; LOWER LIMIT OF QUANTIFICATION; MAXIMUM PLASMA CONCENTRATION; OPTIMIZED ASSAY; QUALITY CONTROL; RECEPTOR BINDING ASSAY; SANDWICH ASSAY; SENSITIVITY ANALYSIS;

ANTIBODIES, MONOCLONAL; BIOMARKERS; BIOSENSING TECHNIQUES; HUMANS; IMMUNOASSAY; LIGANDS; LIMIT OF DETECTION; MAGNETICS; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS;

EID: 84938780044     PISSN: 00068101     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-014-9659-7     Document Type: Article

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