High T1 signal intensity in dentate nucleus after multiple injections of linear gadolinium chelates

Radiology

Volumn 276, Issue 2, 2015, Pages 616-617

  Quattrocchi, Carlo Cosimo ^a   Mallio, Carlo Augusto ^a   Errante, Yuri ^a   Zobel, Bruno Beomonte ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GADODIAMIDE; GADOLINIUM CHELATE; GADOLINIUM PENTETATE MEGLUMINE; CONTRAST MEDIUM; GADOLINIUM PENTETATE; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND;

BLOOD BRAIN BARRIER; BRAIN METASTASIS; BRAIN TUMOR; COHORT ANALYSIS; DENTATE NUCLEUS; DISEASE ASSOCIATION; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SAFETY; EVIDENCE BASED MEDICINE; HUMAN; INJECTION; LETTER; MENINGIOMA; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REPEATED DRUG DOSE; T1 WEIGHTED MAGNETIC RESONANCE IMAGING; TIME; BRAIN DISEASES; CEREBELLUM NUCLEUS; DIAGNOSTIC USE; FEMALE; MALE; PATHOLOGY; PROCEDURES;

BRAIN DISEASES; CEREBELLAR NUCLEI; CONTRAST MEDIA; FEMALE; GADOLINIUM DTPA; HETEROCYCLIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; ORGANOMETALLIC COMPOUNDS;

EID: 84938723273     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2015150464     Document Type: Letter

References (5)

1. Kanda T, Osawa M, Oba H, et al. High signal intensity in dentate nucleus on unenhanced T1-weighted MR images: association with linear versus macrocyclic gadolinium chelate administration. Radiology doi: 10.1148/radiol.14140364. Published online January 27, 2015. Accessed February 19, 2015.
2. Errante Y, Cirimele V, Mallio CA, Di Lazzaro V, Zobel BB, Quattrocchi CC. Progressive increase of T1 signal intensity of the dentate nucleus on unenhanced magnetic resonance images is associated with cumulative doses of intravenously administered gadodiamide in patients with normal renal function, suggesting dechelation. Invest Radiol 2014;49(10):685-690.
3. Kanda T, Ishii K, Kawaguchi H, Kitajima K, Takenaka D. High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology 2014;270(3):834-841.
4. Quattrocchi CC, Mallio CA, Errante Y, et al. Gadodiamide and dentate nucleus T1 hyperintensity in patients with meningioma evaluated by multiple follow-up contrast-enhanced magnetic resonance examinations with no systemic interval therapy. Invest Radiol doi: 10.1097/RLI.0000000000000154. Published online March 11, 2015.
5. Fretellier N, Idée JM, Dencausse A, et al. Comparative in vivo dissociation of gadolinium chelates in renally impaired rats: a relaxometry study. Invest Radiol 2011;46(5):292-300.