Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis

Human molecular genetics

Volumn 23, Issue 24, 2014, Pages 6528-6541

  Wilkins, Heather M ^a   Harris, Janna L ^a   Carl, Steven M ^a   E, Lezi ^a   Lu, Jianghua ^a   Eva Selfridge, J ^a   Roy, Nairita ^a   Hutfles, Lewis ^a   Koppel, Scott ^a   Morris, Jill ^a   Burns, Jeffrey M ^a   Michaelis, Mary L ^a   Michaelis, Elias K ^a   Brooks, William M ^a   Swerdlow, Russell H ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; CYTOCHROME C OXIDASE; DNA BINDING PROTEIN; DOUBLECORTIN PROTEIN; GLUTATHIONE; HIGH MOBILITY GROUP PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LACTIC ACID; MICROTUBULE ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPEPTIDE; NRF1 PROTEIN, MOUSE; NUCLEAR RESPIRATORY FACTOR 1; OXALOACETIC ACID; PEROXISOME-PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA COACTIVATOR-1; PPARGC1A PROTEIN, MOUSE; TFAM PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DNA-BINDING PROTEINS; ELECTRON TRANSPORT COMPLEX IV; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; GLUTATHIONE; HIGH MOBILITY GROUP PROTEINS; HIPPOCAMPUS; INFLAMMATION; INJECTIONS, INTRAPERITONEAL; INSULIN; LACTIC ACID; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL TURNOVER; NEUROGENESIS; NEUROPEPTIDES; NUCLEAR RESPIRATORY FACTOR 1; OXALOACETIC ACID; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84938655903     PISSN: None     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu371     Document Type: Article

References (0)