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Volumn 3, Issue 11, 2014, Pages e962401-1-e962401-3

Priming the pancreatic cancer tumor microenvironment for checkpoint-inhibitor immunotherapy

Author keywords

pancreatic cancer; tumor immunotherapy; tumor vaccines

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; IPILIMUMAB; PROGRAMMED DEATH 1 LIGAND 1;

EID: 84938635509     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/21624011.2014.962401     Document Type: Article
Times cited : (37)

References (20)
  • 1
    • 84892805731 scopus 로고    scopus 로고
    • Cancer statistics, 2014
    • R.Siegel, J.Ma, Z.Zou, A.Jemal. Cancer statistics, 2014. CA: Cancer J Clini 2014; 64(1):9-29; http://dx.doi.org/10.1017/S0009840X13002084
    • (2014) CA: Cancer J Clini , vol.64 , Issue.1 , pp. 9-29
    • Siegel, R.1    Ma, J.2    Zou, Z.3    Jemal, A.4
  • 6
    • 77958050577 scopus 로고    scopus 로고
    • Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
    • 20842054
    • R.E.Royal, C.Levy, K.Turner, A.Mathur, M.Hughes, U.S.Kammula, R.M.Sherry, S.L.Topalian, J.C.Yang, I.Lowy Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma. J Immunother 2010; 33(8):828-33; PMID:20842054; http://dx.doi.org/10.1097/CJI.0b013e3181eec14c
    • (2010) J Immunother , vol.33 , Issue.8 , pp. 828-833
    • Royal, R.E.1    Levy, C.2    Turner, K.3    Mathur, A.4    Hughes, M.5    Kammula, U.S.6    Sherry, R.M.7    Topalian, S.L.8    Yang, J.C.9    Lowy, I.10
  • 7
    • 84904024273 scopus 로고    scopus 로고
    • Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
    • 24714771
    • J.M.Taube, A.Klein, J.R.Brahmer, H.Xu, X.Pan, J.H.Kim, L.Chen, D.M.Pardoll, S.L.Topalian, R.A.Anders. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 2014; 20(19):5064-74; PMID:24714771
    • (2014) Clin Cancer Res , vol.20 , Issue.19 , pp. 5064-5074
    • Taube, J.M.1    Klein, A.2    Brahmer, J.R.3    Xu, H.4    Pan, X.5    Kim, J.H.6    Chen, L.7    Pardoll, D.M.8    Topalian, S.L.9    Anders, R.A.10
  • 8
    • 84876807399 scopus 로고    scopus 로고
    • Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma
    • L.Zheng, J.Xue, E.M.Jaffee, A.Habtezion. Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma. Gastroenterol 2013; 144(6):1230-40; http://dx.doi.org/10.1053/j.gastro.2012.12.042
    • (2013) Gastroenterol , vol.144 , Issue.6 , pp. 1230-1240
    • Zheng, L.1    Xue, J.2    Jaffee, E.M.3    Habtezion, A.4
  • 11
    • 40949157885 scopus 로고    scopus 로고
    • Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation
    • D.Laheru, E.Lutz, J.Burke, B.Biedrzycki, S.Solt, B.Onners, I.Tartakovsky, J.Nemunaitis, D.Le, E.Sugar Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation. Clin Cancer Res: Off J Am Assoc Cancer Res 2008; 14(5):1455-63; http://dx.doi.org/10.1158/1078-0432.CCR-07-0371
    • (2008) Clin Cancer Res: Off J Am Assoc Cancer Res , vol.14 , Issue.5 , pp. 1455-1463
    • Laheru, D.1    Lutz, E.2    Burke, J.3    Biedrzycki, B.4    Solt, S.5    Onners, B.6    Tartakovsky, I.7    Nemunaitis, J.8    Le, D.9    Sugar, E.10
  • 12
    • 79151486551 scopus 로고    scopus 로고
    • A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation
    • 21217520
    • E.Lutz, C.J.Yeo, K.D.Lillemoe, B.Biedrzycki, B.Kobrin, J.Herman, E.Sugar, S.Piantadosi, J.L.Cameron, S.Solt A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation. Ann Surg 2011; 253(2):328-35; PMID:21217520; http://dx.doi.org/10.1097/SLA.0b013e3181fd271c
    • (2011) Ann Surg , vol.253 , Issue.2 , pp. 328-335
    • Lutz, E.1    Yeo, C.J.2    Lillemoe, K.D.3    Biedrzycki, B.4    Kobrin, B.5    Herman, J.6    Sugar, E.7    Piantadosi, S.8    Cameron, J.L.9    Solt, S.10
  • 13
    • 84964314430 scopus 로고    scopus 로고
    • Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation
    • 24942756
    • E.R.Lutz, A.A.Wu, E.Bigelow, R.Sharma, G.Mo, K.Soares, S.Solt, A.Dorman, A.Wamwea, A.Yager Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation. Cancer Immunol Res 2014; 2(7):616-31; PMID:24942756; http://dx.doi.org/10.1158/2326-6066.CIR-14-0027
    • (2014) Cancer Immunol Res , vol.2 , Issue.7 , pp. 616-631
    • Lutz, E.R.1    Wu, A.A.2    Bigelow, E.3    Sharma, R.4    Mo, G.5    Soares, K.6    Solt, S.7    Dorman, A.8    Wamwea, A.9    Yager, A.10
  • 15
    • 80052512017 scopus 로고    scopus 로고
    • Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling
    • 21703392
    • D.Coppola, M.Nebozhyn, F.Khalil, H.Dai, T.Yeatman, A.Loboda, J.J.Mule. Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling. Am J Pathol 2011; 179(1):37-45; PMID:21703392; http://dx.doi.org/10.1016/j.ajpath.2011.03.007
    • (2011) Am J Pathol , vol.179 , Issue.1 , pp. 37-45
    • Coppola, D.1    Nebozhyn, M.2    Khalil, F.3    Dai, H.4    Yeatman, T.5    Loboda, A.6    Mule, J.J.7
  • 17
  • 18
    • 84894514010 scopus 로고    scopus 로고
    • Characteristics of tertiary lymphoid structures in primary cancers
    • J.Goc, W.H.Fridman, C.Sautes-Fridman, M.C.Dieu-Nosjean. Characteristics of tertiary lymphoid structures in primary cancers. Oncoimmunol 2013; 2(12):e26836; http://dx.doi.org/10.4161/onci.26836
    • (2013) Oncoimmunol , vol.2 , Issue.12 , pp. 26836
    • Goc, J.1    Fridman, W.H.2    Sautes-Fridman, C.3    Dieu-Nosjean, M.C.4
  • 19
    • 84859128199 scopus 로고    scopus 로고
    • Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    • J.M.Taube, R.A.Anders, G.D.Young, H.Xu, R.Sharma, T.L.McMiller, S.Chen, A.P.Klein, D.M.Pardoll, S.L.Topalian Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med 2012, 4(127):127ra137; http://dx.doi.org/10.1126/scitranslmed.3003689
    • (2012) Sci Transl Med , vol.4 , Issue.127 , pp. 127
    • Taube, J.M.1    Anders, R.A.2    Young, G.D.3    Xu, H.4    Sharma, R.5    McMiller, T.L.6    Chen, S.7    Klein, A.P.8    Pardoll, D.M.9    Topalian, S.L.10
  • 20
    • 84883207410 scopus 로고    scopus 로고
    • Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer
    • 23924790
    • D.T.Le, E.Lutz, J.N.Uram, E.A.Sugar, B.Onners, S.Solt, L.Zheng, L.A.DiazJr., R.C.Donehower, E.M.Jaffee Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer. J Immunother 2013; 36(7):382-9; PMID:23924790; http://dx.doi.org/10.1097/CJI.0b013e31829fb7a2
    • (2013) J Immunother , vol.36 , Issue.7 , pp. 382-389
    • Le, D.T.1    Lutz, E.2    Uram, J.N.3    Sugar, E.A.4    Onners, B.5    Solt, S.6    Zheng, L.7    Diaz, L.A.8    Donehower, R.C.9    Jaffee, E.M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.