Functional genetic variants in pre-MIR-146a and 196a2 genes are associated with risk of lung cancer in North Indians

Future Oncology

Volumn 11, Issue 15, 2015, Pages 2159-2173

  Sodhi, Kushaldeep Kaur ^a   Bahl, Charu ^a   Singh, Navneet ^b   Behera, Digamber ^b   Sharma, Siddharth ^a  

^a THAPAR UNIVERSITY   (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

genotype; lung cancer; MIR 146a; MIR 196a2; single nucleotide polymorphism

Indexed keywords

GENOMIC DNA; MICRORNA; MICRORNA 146A; MICRORNA 196A2; UNCLASSIFIED DRUG; MIRN146 MICRORNA, HUMAN; MIRN196 MICRORNA, HUMAN;

ADULT; AGED; ARTICLE; CANCER RISK; CANCER SURVIVAL; CONTROLLED STUDY; ETHNICITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INDIAN; LUNG ADENOCARCINOMA; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SQUAMOUS CELL LUNG CARCINOMA; GENETIC PREDISPOSITION; GENETICS; INDIA; KAPLAN MEIER METHOD; LUNG TUMOR; MIDDLE AGED; PATHOLOGY; RISK FACTOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MICRORNAS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84938525514     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.15.143     Document Type: Article

References (44)

1. Bray F. GLOBOCAN 2012 v1.0. Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. http://globocan.iarc.fr
2. Hu Z, Chen J, Tian T et al. Genetic variants of miRNA sequences and non-small cell lung cancer survival. J. Clin. Invest. 118, 2600-2608 (2008
3. Wogan GN, Hecht SS, Felton JS, Conney AH, Loeb LA. Environmental and chemical carcinogenesis. Semin. Cancer Biol. 14, 473-486 (2004
4. Amos CI, Wu X, Spitz MR. Is there a genetic basis for lung cancer susceptibility?. Recent Results Cancer Res. 151, 3-12 (1999
5. Enfield KS, Pikor LA, Martinez VD, Lam WL. Mechanistic roles of noncoding RNAs in lung cancer biology and their clinical implications. Genet. Res. Int. 2012, 737416 (2012
6. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2), 281-297 (2004
7. Xu T, Zhu Y, Wei QK et al. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 29(11), 2126-2131 (2008
8. Hong YS, Kang HJ, Kwak JY et al. Association between microRNA196a2 rs11614913 genotypes and the risk of non-small cell lung cancer in Korean population. J. Prev. Med. Public Health 44(3), 125-130 (2011
9. Hu M, Zhao L, Hu S, Yang J. The association between two common polymorphisms in microRNAs and hepatocellular carcinoma risk in Asian population. PLoS ONE 8(2), e57012 (2013
10. Xu Y, Li L, Xiang X et al. Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: A systematic review and meta-analysis. Gene 527(2), 584-593 (2013
11. Permuth-Wey J, Thompson RC, Nabors LB et al. A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma. J. Neurooncol. 105(3), 639-646 (2011
12. Hung PS, Chang KW, Kao SY, Chu TH, Liu CJ, Lin SC. Association between the rs2910164 polymorphism in pre-miR-146a and oral carcinoma progression. Oral Oncol. 48(5), 404-408 (2012
13. Yue C, Wang M, Ding B et al. Polymorphism of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population. Gynecol Oncol. 122(1), 33-37 (2011
14. Okubo M, Tahara T, Shibata T et al. Association between common genetic variants in pre-microRNAs and gastric cancer risk in Japanese population. Helicobacter 15(6), 524-531 (2010
15. Xu B, Feng N, Li P et al. A functional polymorphism in pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo. Prostate 70(5), 467-472 (2010
16. Wang Z, Cao Y, Jiang C, Yang G, Wu J, Ding Y. Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: A meta-analysis. PLoS ONE 7(6), e40039 (2012
17. Chen C, Zhang Y, Zhang L, Weakley SM, Yao Q. MicroRNA-196: critical roles and clinical applications in development and cancer. J. Cell Mol. Med. 15(1), 14-23 (2011
18. Liu Z, Li G, Wei S, Niu J et al. Genetic variants in selected pre-mircroRNA genes and risk of squamous cell carcinoma of the head and neck. Cancer 116(20), 4753-4760 (2010
19. Guo J, Jin M, Zhang M, Chen K. A genetic variant in miR-196a2 increased digestive system cancer risks: A meta-analysis of 15 case-control studies. PLoS ONE 7(1), e30585 (2012
20. Han Y, Pu R, Han X et al. Associations of pre-miR- 34b/c and pre-miR-196a2 polymorphisms and their multiplicative interactions with hepatitis B virus mutations with hepatocellular carcinoma risk. PLoS ONE 8(3), e58564 (2013
21. Akkiz H, Bayram S, Bekar A, Akgollu E, Uskudar O, Sandikci M. No association of pre-microRNA-146a rs2910164 polymorphism and risk of hepatocellular carcinoma development in Turkish population: A case-control study. Gene 486(1-2), 104-109 (2011
22. Wei J, Zheng L, Liu S et al. MiR-196a2 rs11614913 T > C polymorphism and risk of esophageal cancer in a Chinese population. Hum. Immunol. 74(9), 1199-1205 (2013
23. Field JK, Liloglou T, Xinarianos G et al. Genetic alterations in bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer. Cancer Res. 59(11), 2690-2695 (1999
24. Hao YX, Wang JP, Zhao LF. Associations between three common microRNA polymorphisms and hepatocellular carcinoma risk in Chinese. Asian Pac. J. Cancer Prev. 14(11), 6601-6604 (2013
25. Peng S, Kuang Z, Sheng C, Zhang Y, Xu H, Cheng Q. Association of microRNA-196a-2 gene polymorphism with gastric cancer risk in a Chinese population. Dig. Dis. Sci. 55(8), 2288-2293 (2010
26. Hezova R, Kovarikova A, Bienertova-Vasku J. Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer. World J. Gastroenterol. 18(22), 2827-2831 (2012
27. Zhang J, Wang R, Ma YY et al. Association between single nucleotide polymorphisms in miRNA196a-2 and miRNA146a and susceptibility to hepatocellular carcinoma in a Chinese population. Asian Pac. J. Cancer Prev. 14(11), 6427-6431 (2013
28. Shen J, Ambrosone CB, DiCioccio RA, Odunsi K, Lele SB, Zhao H. A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 29(10), 1963-1966 (2008
29. Zhou F, Zhu H, Luo D et al. A functional polymorphism in pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population. DNA Cell Bio. 31(7), 1290-1295 (2012
30. Zeng Y, Sun QM, Liu NN et al. Correlation between pre-miR-146a C/G polymorphism and gastric cancer risk in Chinese population. World J. Gastroenterol. 16(28), 3578-3583 (2010
31. Jazdzewski K, Murray EL, Franssila K, Jarzab B, Schoenberg L, Chapelle A. Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc. Natl Acad. Sci. USA 105(20), 7269-7274 (2008
32. Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, Benz CC. Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene 27(42), 5643-5647 (2008
33. Li Y, Vadenboom TG, Wang Z et al. miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res. 70(4), 1486-1495 (2010
34. Tian T, Shu Y, Chen J et al. A functional genetic variant in microRNA-196a2 is associated with increased susceptibility of lung cancer in Chinese. Cancer Epidemiol. Biomarkers Prev. 18(4), 1183-1187 (2009
35. Dou T, Wu Q, Chen X et al. A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population. J. Can. Res. Clin. Oncol. 136(12), 1853-1859 (2010
36. George GP, Gangwar R, Mandal RK, Sankhwar SN, Mittal R. Genetic variation in microRNA genes and prostate cancer risk in North Indian population. Mol. Biol. Rep. 38(3), 1609-1615 (2011
37. Schimanski CC, Frerichs K, Rahman F et al. High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells. World J. Gastroenterol. 15(17), 2089-2096 (2009
38. Jeon HS, Lee YH, Lee SY et al. A common polymorphism in pre-microRNA-146a is associated with lung cancer risk in a Korean population. Gene 534(1), 66-71 (2014
39. Yanaihara N, Caplen N, Bowman E et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9, 189-198 (2006
40. Wang S, Tao G, Wu D et al. A functional polymorphism in miR196a2 is associated with risk and prognosis of gastric cancer. Mol. Carcinog. 52(S1), 87-95 (2013
41. Umar M, Upadhyay R, Prakash G, Kumar S, Ghoshal UC, Mittal B. Evaluation of common genetic variants in pre-microRNA in susceptibility and prognosis of esophageal cancer. Mol. Carcinog. 52(S1), 10-18 (2012
42. Kim WH, Min KT, Jeon YJ et al. Association study of microRNA polymorphisms with hepatocellular carcinoma in Korean population. Gene 504(1), 92-97 (2012
43. Hu Z, Chen J, Tian T et al. Genetic variants of miRNA sequences and non-small cell lung cancer survival. J. Clin. Invest. 118(7), 2600-2608 (2008
44. Lin J, Horikawa Y, Tamboli P, Clague J, Wood CG, Wu XW. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. Carcinogenesis 31(10), 1805-1812 (2010