The effects of fusion structure on the expression and bioactivity of human brain natriuretic peptide (BNP) albumin fusion proteins

Current Pharmaceutical Biotechnology

Volumn 15, Issue 9, 2015, Pages 856-863

  Ding, Yuedi ^a   Peng, Ying ^a   Deng, Lili ^a   Wu, Yu ^a   Fu, Qiang ^a   Jin, Jian ^b  

^a BEIJING HOSPITAL   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

Bioactivity; Brain natriuretic peptide; Fusion number; Fusion orientation; Human serum albumin; Pichia pastoris

Indexed keywords

ALBUMIN ANTIBODY; BRAIN NATRIURETIC PEPTIDE; CYCLIC GMP; GUANYLATE CYCLASE; HYBRID PROTEIN; NATRIURETIC PEPTIDE RECEPTOR A; ALBUBNP PROTEIN, HUMAN; ATRIAL NATRIURETIC FACTOR RECEPTOR;

ARTICLE; BIOLOGICAL ACTIVITY; CGMP ASSAY; CONTROLLED STUDY; ENZYME ACTIVITY; FERMENTATION; GENE; HSA GENE; HUMAN; IMMUNOGENICITY; KOMAGATAELLA PASTORIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; WESTERN BLOTTING; CELL LINE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; MOLECULAR GENETICS; PICHIA; PROTEIN CONFORMATION;

BASE SEQUENCE; CELL LINE; CYCLIC GMP; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; NATRIURETIC PEPTIDE, BRAIN; PICHIA; PROTEIN CONFORMATION; RECEPTORS, ATRIAL NATRIURETIC FACTOR; RECOMBINANT FUSION PROTEINS;

EID: 84938514063     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/1389201015666141012182106     Document Type: Article

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