Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?

European Journal of Pediatrics

Volumn 173, Issue 11, 2014, Pages 1429-1435

  Stollar, Fabiola ^a   Alcoba, Gabriel ^a   Gervaix, Alain ^a   Argiroffo, Constance Barazzone ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Bronchiolitis; Disease severity; Outcomes; Respiratory syncytial virus; Virologic testing

Indexed keywords

ANTIINFECTIVE AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GLUCOCORTICOID;

BRONCHIOLITIS, VIRAL; CLINICAL PRACTICE; DRUG COMBINATION; FEMALE; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INFANT; ISOLATION AND PURIFICATION; LABORATORY DIAGNOSIS; MALE; PREDICTIVE VALUE; REPRODUCIBILITY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SWITZERLAND; VIROLOGY;

ADRENERGIC BETA-AGONISTS; ANTI-BACTERIAL AGENTS; BRONCHIOLITIS, VIRAL; DRUG THERAPY, COMBINATION; FALSE NEGATIVE REACTIONS; FEMALE; GLUCOCORTICOIDS; HUMANS; INFANT; MALE; PHYSICIAN'S PRACTICE PATTERNS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SWITZERLAND;

EID: 84938506194     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-014-2334-2     Document Type: Article

References (18)

1. American Academy of Pediatrics (2006) Diagnosis and management of bronchiolitis. Pediatrics 118(4): 1774-1793
2. Bamberger E, Srugo I, Abu Raya B, Segal E, Chaim B, Kassis I, Kugelman A, Miron D (2012) What is the clinical relevance of respiratory syncytial virus bronchiolitis?: findings from a multi-center, prospective study. Eur J Clin Microbiol Infect Dis 31(12):3323–3330
3. Barben J, Hammer J (2003) Current management of acute bronchiolitis in Switzerland. Swiss Med Wkly 133(1–2):9–15
4. Barben J, Kuehni CE, Trachsel D, Hammer J, Swiss Paediatric Respiratory Research (2008) Management of acute bronchiolitis: can evidence based guidelines alter clinical practice? Thorax 63(12):1103–1109
5. Damore D, Mansbach JM, Clark S, Ramundo M, Camargo CA Jr (2008) Prospective multicenter bronchiolitis study: predicting intensive care unit admissions. Acad Emerg Med 15(10):887–894
6. Garcia CG, Bhore R, Soriano-Fallas A, Trost M, Chason R, Ramilo O, Mejias A (2010) Risk factors in children hospitalized with RSV bronchiolitis versus non-RSV bronchiolitis. Pediatrics 126(6):e1453–e1460
7. Hervas D, Reina J, Yanez A, del Valle JM, Figuerola J, Hervas JA (2012) Epidemiology of hospitalization for acute bronchiolitis in children: differences between RSV and non-RSV bronchiolitis. Eur J Clin Microbiol Infect Dis 31(8):1975–1981
8. Manoha C, Espinosa S, Aho SL, Huet F, Pothier P (2007) Epidemiological and clinical features of hMPV, RSV and RVs infections in young children. J Clin Virol 38(3):221–226
9. Mansbach JM, Clark S, Christopher NC, LoVecchio F, Kunz S, Acholonu U, Camargo CA Jr (2008) Prospective multicenter study of bronchiolitis: predicting safe discharges from the emergency department. Pediatrics 121(4):680–688
10. Mansbach JM, Piedra PA, Teach SJ, Sullivan AF, Forgey T, Clark S, Espinola JA, Camargo CA Jr (2012) Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis. Arch Pediatr Adolesc Med 166(8):700–706
11. Marguet C, Lubrano M, Gueudin M, Le Roux P, Deschildre A, Forget C, Couderc L, Siret D, Donnou MD, Bubenheim M, Vabret A, Freymuth F (2009) In very young infants severity of acute bronchiolitis depends on carried viruses. PLoS ONE 4(2):e4596
12. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, O’Brien KL, Roca A, Wright PF, Bruce N, Chandran A, Theodoratou E, Sutanto A, Sedyaningsih ER, Ngama M, Munywoki PK, Kartasasmita C, Simões EAF, Rudan I, Weber MW, Campbell H (2010) Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 375(9725):1545–1555
13. Norwood A, Mansbach JM, Clark S, Waseem M, Camargo CA Jr (2010) Prospective multicenter study of bronchiolitis: predictors of an unscheduled visit after discharge from the emergency department. Acad Emerg Med 17(4):376–382
14. Papoff P, Moretti C, Cangiano G, Bonci E, Roggini M, Pierangeli A, Scagnolari C, Antonelli G, Midulla F (2011) Incidence and predisposing factors for severe disease in previously healthy term infants experiencing their first episode of bronchiolitis. Acta Paediatr 100(7):e17–e23
15. Richard N, Komurian-Pradel F, Javouhey E, Perret M, Rajoharison A, Bagnaud A, Vernet G, Lina B, Floret D, Paranhos-Baccala G (2008) The impact of dual viral infection in infants admitted to a pediatric intensive care unit associated with severe bronchiolitis. Pediatr Infect Dis J 27(3):213–217
16. Sommer C, Resch B, Simoes EA (2011) Risk factors for severe respiratory syncytial virus lower respiratory tract infection. Open Microbiol J 5:144–154
17. Swingler GH, Hussey GD, Zwarenstein M (1998) Randomised controlled trial of clinical outcome after chest radiograph in ambulatory acute lower-respiratory infection in children. Lancet 351(9100):404–408
18. Zorc JJ, Hall CB (2010) Bronchiolitis: recent evidence on diagnosis and management. Pediatrics 125(2):342–349