메뉴 건너뛰기




Volumn 29, Issue 3, 2015, Pages 243-255

Preservation of Glucagon-Like Peptide-1 Level Attenuates Angiotensin II-Induced Tissue Fibrosis by Altering AT1/AT2 Receptor Expression and Angiotensin-Converting Enzyme 2 Activity in Rat Heart

Author keywords

ACE2; Angiotensin II receptors; Cardiac fibrosis; Collagen; Dipeptidyl peptidase 4; Glucagon like peptide 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; LINAGLIPTIN; LIRAGLUTIDE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; COLLAGEN; DIPEPTIDYL CARBOXYPEPTIDASE; GLUCAGON LIKE PEPTIDE 1; SMAD PROTEIN;

EID: 84938415449     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-015-6592-7     Document Type: Article
Times cited : (69)

References (44)
  • 1
    • 81855184881 scopus 로고    scopus 로고
    • Repair after myocardial infarction between fantasy and reality
    • PID: 22115639
    • Liehn EA, Postea O, Curaj A, Marx N. Repair after myocardial infarction between fantasy and reality. J Am Coll Cardiol. 2011;58:2357–62.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2357-2362
    • Liehn, E.A.1    Postea, O.2    Curaj, A.3    Marx, N.4
  • 2
    • 1442348124 scopus 로고    scopus 로고
    • Fibrosis in hypertension heart disease: focus on cardiac fibroblasts
    • COI: 1:CAS:528:DC%2BD2cXivFyqur0%3D, PID: 15106793
    • Weber KT. Fibrosis in hypertension heart disease: focus on cardiac fibroblasts. J Hypertens. 2004;22:47–60.
    • (2004) J Hypertens , vol.22 , pp. 47-60
    • Weber, K.T.1
  • 3
    • 84861306256 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers for treatment of ischemic heart disease: future research needs prioritization
    • COI: 1:CAS:528:DC%2BC38Xnt1Kqtro%3D, PID: 22607854
    • Crowley MJ, Powers BJ, Myers ER, McBroom AJ, Sanders G. Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers for treatment of ischemic heart disease: future research needs prioritization. Am Heart J. 2012;163:777–82.
    • (2012) Am Heart J , vol.163 , pp. 777-782
    • Crowley, M.J.1    Powers, B.J.2    Myers, E.R.3    McBroom, A.J.4    Sanders, G.5
  • 4
    • 56149096807 scopus 로고    scopus 로고
    • AT2 receptors: functional relevance in cardiovascular disease
    • COI: 1:CAS:528:DC%2BD1cXhsVWrsL7N, PID: 18804122
    • Jones ES, Vinh A, McCarthy CA, Gaspari TA, Widdop RE. AT2 receptors: functional relevance in cardiovascular disease. Pharmacol Ther. 2008;120:292–316.
    • (2008) Pharmacol Ther , vol.120 , pp. 292-316
    • Jones, E.S.1    Vinh, A.2    McCarthy, C.A.3    Gaspari, T.A.4    Widdop, R.E.5
  • 6
    • 77956896591 scopus 로고    scopus 로고
    • Angiotensin II revisited: new roles in inflammation, immunology and aging
    • COI: 1:CAS:528:DC%2BC3cXht12jsbrO, PID: 20597104
    • Benigni A, Cassis P, Remuzzi G. Angiotensin II revisited: new roles in inflammation, immunology and aging. EMBO Mol Med. 2010;2:247–57.
    • (2010) EMBO Mol Med , vol.2 , pp. 247-257
    • Benigni, A.1    Cassis, P.2    Remuzzi, G.3
  • 7
    • 48549095799 scopus 로고    scopus 로고
    • Angiotensin receptor blockers: current status and future prospects
    • COI: 1:CAS:528:DC%2BD1cXps1Ggsbk%3D, PID: 18691475
    • Ram CVS. Angiotensin receptor blockers: current status and future prospects. Am J Med. 2008;121:656–63.
    • (2008) Am J Med , vol.121 , pp. 656-663
    • Ram, C.V.S.1
  • 8
    • 20444430437 scopus 로고    scopus 로고
    • Angiotensin II receptor blockade and ventricular remodeling
    • COI: 1:CAS:528:DC%2BD2MXlsFejt70%3D, PID: 16088851
    • Anavekar NS, Solomon SD. Angiotensin II receptor blockade and ventricular remodeling. JRAAS. 2005;6:43–8.
    • (2005) JRAAS , vol.6 , pp. 43-48
    • Anavekar, N.S.1    Solomon, S.D.2
  • 9
    • 2642575030 scopus 로고    scopus 로고
    • Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists
    • PID: 15173039
    • Azizi M, Menard J. Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists. Circulation. 2004;109:2492–9.
    • (2004) Circulation , vol.109 , pp. 2492-2499
    • Azizi, M.1    Menard, J.2
  • 10
    • 84895164679 scopus 로고    scopus 로고
    • Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation
    • COI: 1:CAS:528:DC%2BC2cXjt1Sht70%3D, PID: 23889512
    • Pabreja K, Mohd MA, Kode C, Wootten D, Furness SGB. Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation. Br J Pharmacol. 2014;171:1114–28.
    • (2014) Br J Pharmacol , vol.171 , pp. 1114-1128
    • Pabreja, K.1    Mohd, M.A.2    Kode, C.3    Wootten, D.4    Furness, S.G.B.5
  • 12
    • 84855481995 scopus 로고    scopus 로고
    • Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified prospective, and adjudicated mata-analysis of a phase 3 programme
    • COI: 1:CAS:528:DC%2BC38XktVOltbw%3D, PID: 22234149
    • Johansen OE, Neubache D, Eynatten MV, Patel S, Woerle HJ. Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified prospective, and adjudicated mata-analysis of a phase 3 programme. Cardiovasc Diabetol. 2012;11:3–13.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 3-13
    • Johansen, O.E.1    Neubache, D.2    Eynatten, M.V.3    Patel, S.4    Woerle, H.J.5
  • 13
    • 84880274333 scopus 로고    scopus 로고
    • The emerging role of dipeptidyl peptidase-4 inhibitors in cardiovascular protection: current position and perspectives
    • PID: 23645229
    • Wang XM, Yang YJ, Wu YJ. The emerging role of dipeptidyl peptidase-4 inhibitors in cardiovascular protection: current position and perspectives. Cardiovasc Drugs Ther. 2013;27:297–307.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 297-307
    • Wang, X.M.1    Yang, Y.J.2    Wu, Y.J.3
  • 14
    • 77956893157 scopus 로고    scopus 로고
    • Liraglutide: the therapeutic promise from animal models
    • Knudsen LB. Liraglutide: the therapeutic promise from animal models. Int J Clin Pract. 2010;64:4–11.
    • (2010) Int J Clin Pract , vol.64 , pp. 4-11
    • Knudsen, L.B.1
  • 15
    • 84862692484 scopus 로고    scopus 로고
    • Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity
    • Kern M, Kioting N, Niessen HG, Thomas L, Stiller D, Mark M, et al. Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity. PLoS One. 2012;7:e38744.
    • (2012) PLoS One , vol.e38744 , pp. 7
    • Kern, M.1    Kioting, N.2    Niessen, H.G.3    Thomas, L.4    Stiller, D.5    Mark, M.6
  • 16
    • 84868641492 scopus 로고    scopus 로고
    • Curcumin promotes cardiac repair and ameliorates cardiac dysfunction following myocardial infarction
    • Wang NP, Wang ZF, Tootle S, Philip TJ, Zhao ZQ. Curcumin promotes cardiac repair and ameliorates cardiac dysfunction following myocardial infarction. Br J Pharmacol. 2012;167:1550–62.
    • (2012) Br J Pharmacol , vol.167 , pp. 1550-1562
    • Wang, N.P.1    Wang, Z.F.2    Tootle, S.3    Philip, T.J.4    Zhao, Z.Q.5
  • 17
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptide by human angiotensin-converting enzyme-related carboxypeptidase
    • Vickers C, Hales P, Kaushik V, Dick L, Gavin J, Tang K, et al. Hydrolysis of biological peptide by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem. 2002;277:14838–43.
    • (2002) J Biol Chem , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3    Dick, L.4    Gavin, J.5    Tang, K.6
  • 18
    • 84892385757 scopus 로고    scopus 로고
    • Optimizing cardioprotection during myocardial ischemia: targeting potential intracellular pathways with glucagon-like peptide-1
    • PID: 24410815
    • Clarke SJ, McCormick LM, Dutka DP. Optimizing cardioprotection during myocardial ischemia: targeting potential intracellular pathways with glucagon-like peptide-1. Cardiovasc Diabetol. 2014;13:12–22.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 12-22
    • Clarke, S.J.1    McCormick, L.M.2    Dutka, D.P.3
  • 19
    • 84899467577 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 endothelial cell by repressing nuclear factor-kappa B activation
    • COI: 1:CAS:528:DC%2BC3sXhsFSktbnJ, PID: 23657563
    • Dai Y, Mehta JL, Chen M. Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 endothelial cell by repressing nuclear factor-kappa B activation. Cardiovasc Drugs Ther. 2013;27:371–80.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 371-380
    • Dai, Y.1    Mehta, J.L.2    Chen, M.3
  • 20
    • 64649102619 scopus 로고    scopus 로고
    • GLP-1 receptor agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice
    • COI: 1:CAS:528:DC%2BD1MXktleiu7o%3D, PID: 19151200
    • Noyan-Ashraf MH, Momen MA, Ban K, Sadi AM, Zhou YQ, Riazi AM, et al. GLP-1 receptor agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice. Diabetes. 2009;58:975–83.
    • (2009) Diabetes , vol.58 , pp. 975-983
    • Noyan-Ashraf, M.H.1    Momen, M.A.2    Ban, K.3    Sadi, A.M.4    Zhou, Y.Q.5    Riazi, A.M.6
  • 21
    • 34548545405 scopus 로고    scopus 로고
    • Myocardial ischemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway
    • COI: 1:CAS:528:DC%2BD2sXhtVagtbnM, PID: 17541736
    • Bose AK, Mocanu MM, Carr RD, Yellon DM. Myocardial ischemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway. Cardiovasc Drugs Ther. 2007;21:253–6.
    • (2007) Cardiovasc Drugs Ther , vol.21 , pp. 253-256
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Yellon, D.M.4
  • 22
    • 84860159344 scopus 로고    scopus 로고
    • GLP-1 and cardioprotection: from bench to bedside
    • COI: 1:CAS:528:DC%2BC38XmtVegtL8%3D, PID: 22419668
    • Ravassa S, Zudaire A, Diez J. GLP-1 and cardioprotection: from bench to bedside. Cardiovasc Res. 2012;94:316–23.
    • (2012) Cardiovasc Res , vol.94 , pp. 316-323
    • Ravassa, S.1    Zudaire, A.2    Diez, J.3
  • 23
    • 7444272132 scopus 로고    scopus 로고
    • Angiotensin AT2 receptor contributes to cardiovascular remodeling of aged rats during chronic AT1 receptor blockade
    • COI: 1:CAS:528:DC%2BD2cXpt1aqs74%3D, PID: 15522279
    • Jones ES, Black MJ, Widdop RE. Angiotensin AT2 receptor contributes to cardiovascular remodeling of aged rats during chronic AT1 receptor blockade. J Mol Cell Cardiol. 2004;37:1023–30.
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 1023-1030
    • Jones, E.S.1    Black, M.J.2    Widdop, R.E.3
  • 24
    • 78249248682 scopus 로고    scopus 로고
    • Cardiac pathologies in relation to Smad-dependent pathways
    • PID: 20650957
    • Yuan SM, Jing H. Cardiac pathologies in relation to Smad-dependent pathways. Interact Cardiovasc Thorac Surg. 2010;11:455–60.
    • (2010) Interact Cardiovasc Thorac Surg , vol.11 , pp. 455-460
    • Yuan, S.M.1    Jing, H.2
  • 25
    • 29144486106 scopus 로고    scopus 로고
    • The complex pattern of SMAD signaling in the cardiovascular system
    • COI: 1:CAS:528:DC%2BD2MXhtlGisb%2FI, PID: 16107248
    • Euler-Taimor G, Heger J. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc Res. 2006;69:15–25.
    • (2006) Cardiovasc Res , vol.69 , pp. 15-25
    • Euler-Taimor, G.1    Heger, J.2
  • 26
    • 34047148354 scopus 로고    scopus 로고
    • The role of TGF-β signaling in myocardial infarction and cardiac remodeling
    • COI: 1:CAS:528:DC%2BD2sXjvFehs7g%3D, PID: 17109837
    • Bujak M, Frangogiannis NG. The role of TGF-β signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res. 2007;74:184–95.
    • (2007) Cardiovasc Res , vol.74 , pp. 184-195
    • Bujak, M.1    Frangogiannis, N.G.2
  • 27
    • 34547892633 scopus 로고    scopus 로고
    • Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts
    • COI: 1:CAS:528:DC%2BD2sXptlyrsbY%3D, PID: 17513491
    • Wang B, Omara A, Angelovska T, Drobic V, Rattan SG, Jones SC, et al. Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts. Am J Physiol Heart Circ Physiol. 2007;293:H1282–90.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H1282-H1290
    • Wang, B.1    Omara, A.2    Angelovska, T.3    Drobic, V.4    Rattan, S.G.5    Jones, S.C.6
  • 28
    • 0034537229 scopus 로고    scopus 로고
    • Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro
    • COI: 1:CAS:528:DC%2BD3cXptFSlsL8%3D, PID: 11087260
    • Hao JM, Wang BQ, Jones SC, Jassal DS, Dixon IMC. Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro. Am J Physiol Heart Circ Physiol. 2000;279:H3020–30.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279 , pp. H3020-H3030
    • Hao, J.M.1    Wang, B.Q.2    Jones, S.C.3    Jassal, D.S.4    Dixon, I.M.C.5
  • 29
    • 21144438717 scopus 로고    scopus 로고
    • A marked attenuation of production of collagen type I from cardiac fibroblasts by dehydroepiandrosterone
    • COI: 1:CAS:528:DC%2BD2MXlsVylsLk%3D, PID: 15657092
    • Iwasaki T, Mukasa K, Yoneda M, Ito S, Yamada Y, Mori Y, et al. A marked attenuation of production of collagen type I from cardiac fibroblasts by dehydroepiandrosterone. Am J Physiol Endocrinol Metab. 2005;288:E1222–8.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E1222-E1228
    • Iwasaki, T.1    Mukasa, K.2    Yoneda, M.3    Ito, S.4    Yamada, Y.5    Mori, Y.6
  • 30
    • 60949097622 scopus 로고    scopus 로고
    • Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts
    • COI: 1:CAS:528:DC%2BD1MXivVehsbc%3D, PID: 19374881
    • Gao XR, He XY, Luo B, Peng LY, Lin J, Zuo ZY. Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts. Eur J Pharmacol. 2009;606:115–20.
    • (2009) Eur J Pharmacol , vol.606 , pp. 115-120
    • Gao, X.R.1    He, X.Y.2    Luo, B.3    Peng, L.Y.4    Lin, J.5    Zuo, Z.Y.6
  • 31
    • 79958032667 scopus 로고    scopus 로고
    • Angiotensin II infusion-induced inflammation, monocytic fibroblast precursor infiltration and cardiac fibrosis are pressure dependent
    • COI: 1:CAS:528:DC%2BC3MXlsFGqs7Y%3D, PID: 21373977
    • Qi GM, Jia L, Li YL, Bian Y, Cheng JZ, Li HH, et al. Angiotensin II infusion-induced inflammation, monocytic fibroblast precursor infiltration and cardiac fibrosis are pressure dependent. Cardiovasc Toxicol. 2011;11:157–67.
    • (2011) Cardiovasc Toxicol , vol.11 , pp. 157-167
    • Qi, G.M.1    Jia, L.2    Li, Y.L.3    Bian, Y.4    Cheng, J.Z.5    Li, H.H.6
  • 32
    • 84878587722 scopus 로고    scopus 로고
    • The novel DPP-4 inhibitor linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats
    • PID: 22217485
    • Hocher B, Sharkovska Y, Mark M, Klein T, Pfab T. The novel DPP-4 inhibitor linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats. Int J Cardiol. 2013;167:87–93.
    • (2013) Int J Cardiol , vol.167 , pp. 87-93
    • Hocher, B.1    Sharkovska, Y.2    Mark, M.3    Klein, T.4    Pfab, T.5
  • 33
    • 84919712450 scopus 로고    scopus 로고
    • DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway
    • COI: 1:CAS:528:DC%2BC2cXhtFCqtbvF, PID: 25022544
    • Dai Y, Dai D, Wang XW, Ding ZF, Mehta JL. DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway. Cardiovasc Drugs Ther. 2014;28:425–32.
    • (2014) Cardiovasc Drugs Ther , vol.28 , pp. 425-432
    • Dai, Y.1    Dai, D.2    Wang, X.W.3    Ding, Z.F.4    Mehta, J.L.5
  • 34
    • 84884178268 scopus 로고    scopus 로고
    • Linagliptin: a thorough characterization beyond its clinical efficacy
    • Sortino MA, Sinagra T, Canonico PL. Linagliptin: a thorough characterization beyond its clinical efficacy. Front Endocrinol. 2013;4:1–9.
    • (2013) Front Endocrinol , vol.4 , pp. 1-9
    • Sortino, M.A.1    Sinagra, T.2    Canonico, P.L.3
  • 35
    • 33846256550 scopus 로고    scopus 로고
    • ACE2 of the heart: from angiotensin I to angiotensin (1-7)
    • COI: 1:CAS:528:DC%2BD2sXltVSqsg%3D%3D, PID: 17049503
    • Keidar S, Kaplan M, Gamliel -Lazarovich A. ACE2 of the heart: from angiotensin I to angiotensin (1-7). Cardiovasc Res. 2007;73:463–9.
    • (2007) Cardiovasc Res , vol.73 , pp. 463-469
    • Keidar, S.1    Kaplan, M.2    Gamliel -Lazarovich, A.3
  • 36
    • 33645834948 scopus 로고    scopus 로고
    • Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
    • COI: 1:CAS:528:DC%2BD28XitlSgtLc%3D, PID: 16505206
    • Yamamoto K, Ohishi M, Katsuya T, Ito N, Ikushima M, Kaibe M, et al. Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension. 2006;47:718–26.
    • (2006) Hypertension , vol.47 , pp. 718-726
    • Yamamoto, K.1    Ohishi, M.2    Katsuya, T.3    Ito, N.4    Ikushima, M.5    Kaibe, M.6
  • 38
    • 84861528870 scopus 로고    scopus 로고
    • Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2 - null mice
    • COI: 1:CAS:528:DC%2BC38XntVSgtro%3D, PID: 22508831
    • Patel VB, Bodiga S, Fan D, Das SK, Wang ZH, Wang W, et al. Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2 - null mice. Hypertension. 2012;59:1195–203.
    • (2012) Hypertension , vol.59 , pp. 1195-1203
    • Patel, V.B.1    Bodiga, S.2    Fan, D.3    Das, S.K.4    Wang, Z.H.5    Wang, W.6
  • 40
    • 84897852105 scopus 로고    scopus 로고
    • GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody
    • PID: 24467746
    • Pyke C, Heller S, Kirk RK, Orskov C, Reedtz-Runge S, Kaastrup P, et al. GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody. Endocrinology. 2014;155:1280–90.
    • (2014) Endocrinology , vol.155 , pp. 1280-1290
    • Pyke, C.1    Heller, S.2    Kirk, R.K.3    Orskov, C.4    Reedtz-Runge, S.5    Kaastrup, P.6
  • 41
    • 28144441354 scopus 로고    scopus 로고
    • Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy
    • COI: 1:CAS:528:DC%2BD28XlslGnug%3D%3D, PID: 16024574
    • Nikolaidis LA, Elahi D, Shen YT, Shannon RP. Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2005;289:H2401–8.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H2401-H2408
    • Nikolaidis, L.A.1    Elahi, D.2    Shen, Y.T.3    Shannon, R.P.4
  • 42
    • 82955217670 scopus 로고    scopus 로고
    • Inflammation alters angiotensin converting enzymes (ACE and ACE-2) balance in rat heart
    • Hanafy H, Tavasoli M, Jamali F. Inflammation alters angiotensin converting enzymes (ACE and ACE-2) balance in rat heart. Inflammation. 2011;34:609–13.
    • (2011) Inflammation , vol.34 , pp. 609-613
    • Hanafy, H.1    Tavasoli, M.2    Jamali, F.3
  • 43
    • 85007193610 scopus 로고    scopus 로고
    • Linagliptin alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis
    • COI: 1:CAS:528:DC%2BC2cXhsFGls7nI, PID: 24048504
    • Klein T, Fuji M, Sandel J, Shibazaki Y, Wakamatsu K, Mark M, et al. Linagliptin alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis. Med Mol Morphol. 2014;47:137–49.
    • (2014) Med Mol Morphol , vol.47 , pp. 137-149
    • Klein, T.1    Fuji, M.2    Sandel, J.3    Shibazaki, Y.4    Wakamatsu, K.5    Mark, M.6
  • 44
    • 78149493266 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure
    • PID: 21080957
    • Liu Q, Anderson C, Broyde A, Polizzi C, Fernandez R, Baron A, et al. Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure. Cardiovasc Diabetol. 2010;9:76–90.
    • (2010) Cardiovasc Diabetol , vol.9 , pp. 76-90
    • Liu, Q.1    Anderson, C.2    Broyde, A.3    Polizzi, C.4    Fernandez, R.5    Baron, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.