Gene-arsenic interaction in longitudinal changes of blood pressure: Findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh

Toxicology and Applied Pharmacology

Volumn 288, Issue 1, 2015, Pages 95-105

  Farzan, Shohreh F ^a,b   Karagas, Margaret R ^a   Jiang, Jieying ^b   Wu, Fen ^b   Liu, Mengling ^b   Newman, Jonathan D ^b   Jasmine, Farzana ^c   Kibriya, Muhammad G ^c   Paul Brutus, Rachelle ^c   Parvez, Faruque ^d   Argos, Maria ^c   Bryan, Molly Scannell ^c   Eunus, Mahbub ^c   Ahmed, Alauddin ^c   Islam, Tariqul ^c   Rakibuz Zaman, Muhammad ^c   Hasan, Rabiul ^c   Sarwar, Golam ^c   Slavkovich, Vesna ^d   Graziano, Joseph ^d   Ahsan, Habibul ^c   Chen, Yu ^b   more..

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d Department of Medicine   (United States)

Author keywords

Arsenic; Blood pressure; CYBA; HEALS; Longitudinal; SNPs

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTIHYPERTENSIVE AGENT; APOLIPOPROTEIN E; ARSENIC; ARSENITE METHYLTRANSFERASE; CYSTATHIONINE BETA SYNTHASE; CYTOCHROME B; DRINKING WATER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE S TRANSFERASE OMEGA 1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; PURINE NUCLEOSIDE PHOSPHORYLASE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; WELL WATER; WATER POLLUTANT;

ADULT; AEROBIC METABOLISM; AGED; ARTICLE; ATOMIC ABSORPTION; BANGLADESH; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE VARIABILITY; BLOOD VESSEL FUNCTION; BODY MASS; COHORT ANALYSIS; CONTROLLED STUDY; CREATININE URINE LEVEL; DIASTOLIC BLOOD PRESSURE; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW UP; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; HYPERTENSION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PROSPECTIVE STUDY; PULSE PRESSURE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; ADOLESCENT; ADVERSE EFFECTS; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PATHOPHYSIOLOGY; PHENOTYPE; RISK ASSESSMENT; RISK FACTOR; TIME FACTOR; WATER POLLUTANT; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ARSENIC; BANGLADESH; BLOOD PRESSURE; ENVIRONMENTAL EXPOSURE; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; WATER POLLUTANTS, CHEMICAL; WATER WELLS; YOUNG ADULT;

EID: 84938333894     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.07.017     Document Type: Article

References (70)

1. Abhyankar L.N., Jones M.R., Guallar E., Navas-Acien A. Arsenic exposure and hypertension: a systematic review. Environ. Health Perspect. 2012, 120:494-500.
2. Agusa T., Iwata H., Fujihara J., Kunito T., Takeshita H., et al. Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam. Toxicol. Appl. Pharmacol. 2010, 242:352-362.
3. Ahsan H., Chen Y., Parvez F., Argos M., Hussain A.I., et al. Health Effects of Arsenic Longitudinal Study (HEALS): description of a multidisciplinary epidemiologic investigation. J. Expo. Sci. Environ. Epidemiol. 2006, 16:191-205.
4. Alharbi K.K., Khan I.A., Syed R. Association of apolipoprotein E polymorphism with type 2 diabetes mellitus in a Saudi population. DNA Cell Biol. 2014, 33:637-641.
5. Barbagallo I., Galvano F., Frigiola A., Cappello F., Riccioni G., et al. Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases. Antioxid. Redox Signal. 2013, 18:507-521.
6. Benjamini Y., Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B Methodol. 1995, 57:289-300.
7. Chang M.H., Yesupriya A., Ned R.M., Mueller P.W., Dowling N.F. Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination Survey. BMC Med. Genet. 2010, 11:62.
8. Chaudhary R., Likidlilid A., Peerapatdit T., Tresukosol D., Srisuma S., et al. Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease. Cardiovasc. Diabetol. 2012, 11:36.
9. Chen Y., Santella R.M., Kibriya M.G., Wang Q., Kappil M., et al. Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion molecules. Environ. Health Perspect. 2007, 115:1415-1420.
10. Chen Y., Factor-Litvak P., Howe G.R., Graziano J.H., Brandt-Rauf P., et al. Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional study. Am. J. Epidemiol. 2007, 165:541-552.
11. Chen Y., van Geen A., Graziano J.H., Pfaff A., Madajewicz M., et al. Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, Bangladesh. Environ. Health Perspect. 2007, 115:917-923.
12. Chen Y., Ahsan H., Slavkovich V., Peltier G.L., Gluskin R.T., et al. No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in Bangladesh. Environ. Health Perspect. 2010, 118:1299-1305.
13. Chen Y., Graziano J.H., Parvez F., Liu M., Slavkovich V., et al. Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study. BMJ 2011, 342:d2431.
14. Chen S.C., Chen C.C., Kuo C.Y., Huang C.H., Lin C.H., et al. Elevated risk of hypertension induced by arsenic exposure in Taiwanese rural residents: possible effects of manganese superoxide dismutase (MnSOD) and 8-oxoguanine DNA glycosylase (OGG1) genes. Arch. Toxicol. 2012, 86:869-878.
15. Cheng Z., Zheng Y., Mortlock R., Van Geen A. Rapid multi-element analysis of groundwater by high-resolution inductively coupled plasma mass spectrometry. Anal. Bioanal. Chem. 2004, 379:512-518.
16. Cheng Z., van Geen A., Seddique A.A., Ahmed K.M. Limited temporal variability of arsenic concentrations in 20 wells monitored for 3years in Araihazar, Bangladesh. Environ. Sci. Technol. 2005, 39:4759-4766.
17. Chou W.C., Jie C., Kenedy A.A., Jones R.J., Trush M.A., et al. Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:4578-4583.
18. Chung C.J., Hsueh Y.M., Bai C.H., Huang Y.K., Huang Y.L., et al. Polymorphisms in arsenic metabolism genes, urinary arsenic methylation profile and cancer. Cancer Causes Control 2009, 20:1653-1661.
19. Cooper K.L., Liu K.J., Hudson L.G. Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: contribution of NADPH oxidase. Free Radic. Biol. Med. 2009, 47:381-388.
20. Engstrom K., Vahter M., Mlakar S.J., Concha G., Nermell B., et al. Polymorphisms in arsenic (+III oxidation state) methyltransferase (AS3MT) predict gene expression of AS3MT as well as arsenic metabolism. Environ. Health Perspect. 2011, 119:182-188.
21. Farzan S.F., Chen Y., Wu F., Jiang J., Liu M., et al. Blood pressure changes in relation to arsenic exposure in a U.S. pregnancy cohort. Environ. Health Perspect. 2015, (Epub ahead of print).
22. Farzan S.F., Chen Y., Rees J.R., Zens M.S., Karagas M.R. Risk of death from cardiovascular disease associated with low-level arsenic exposure among long-term smokers in a US population-based study. Toxicol. Appl. Pharmacol. 2015, pii: S0041-008X(15)30003-X. http://dx.doi.org/10.1016/j.taap.2015.05.013 (Epub ahead of print).
23. Flora S.J.S. Arsenic-induced oxidative stress and its reversibility. Free Radic. Biol. Med. 2011, 51:257-281.
24. Franklin S.S., Lopez V.A., Wong N.D., Mitchell G.F., Larson M.G., et al. Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study. Circulation 2009, 119:243-250.
25. F-SNP database Queen's University, Ontario, Canada. (accessed 5 March 2015). http://compbio.cs.queensu.ca/F-SNP.
26. Haider A.W., Larson M.G., Franklin S.S., Levy D. Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham Heart Study. Ann. Intern. Med. 2003, 138:10-16.
27. Hall M.N., Niedzwiecki M., Liu X., Harper K.N., Alam S., et al. Chronic arsenic exposure and blood glutathione and glutathione disulfide concentrations in Bangladeshi adults. Environ. Health Perspect. 2013, 121:1068-1074.
28. Heilpern K. Pathophysiology of hypertension. Ann. Emerg. Med. 2008, 51:S5-S6.
29. International Hapmap Project. (accessed 5 March 2015). http://hapmap.ncbi.nlm.nih.gov.
30. Jiang J., Liu M., Parvez F., Wang B., Wu F., et al. Association between arsenic exposure from drinking water and longitudinal change in blood pressure among HEALS cohort participants. Environ. Health Perspect. 2015, (Epub ahead of print).
31. Jiang J., Liu M., Parvez F., Wang B., Wu F., et al. Association of major dietary patterns and blood pressure longitudinal change in Bangladesh. J. Hypertens. 2015, 33:1193-1200.
32. Johnson T., Gaunt T.R., Newhouse S.J., Padmanabhan S., Tomaszewski M., et al. Blood pressure loci identified with a gene-centric array. Am. J. Hum. Genet. 2011, 89:688-700.
33. Jomova K., Jenisova Z., Feszterova M., Baros S., Liska J., et al. Arsenic: toxicity, oxidative stress and human disease. J. Appl. Toxicol. 2011, 31:95-107.
34. Lee P.H., Shatkay H. F-SNP: computationally predicted functional SNPs for disease association studies. Nucleic Acids Res. 2008, 36:D820-D824.
35. Lee P.C., Ho I.C., Lee T.C. Oxidative stress mediates sodium arsenite-induced expression of heme oxygenase-1, monocyte chemoattractant protein-1, and interleukin-6 in vascular smooth muscle cells. Toxicol. Sci. 2005, 85:541-550.
36. Lewington S., Clarke R., Qizilbash N., Peto R., Collins R., et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002, 360:1903-1913.
37. Moon K.A., Guallar E., Umans J.G., Devereux R.B., Best L.G., et al. Association between exposure to low to moderate arsenic levels and incident cardiovascular disease a prospective cohort study. Ann. Intern. Med. 2013, 159:649-659.
38. Mordukhovich I., Wright R.O., Amarasiriwardena C., Baja E., Baccarelli A., et al. Association between low-level environmental arsenic exposure and QT interval duration in a general population study. Am. J. Epidemiol. 2009, 170:739-746.
39. Mordukhovich I., Wright R.O., Hu H., Amarasiriwardena C., Baccarelli A., et al. Associations of toenail arsenic, cadmium, mercury, manganese, and lead with blood pressure in the normative aging study. Environ. Health Perspect. 2012, 120:98-104.
40. Moreno M.U., San Jose G., Fortuno A., Beloqui O., Redon J., et al. A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension. J. Hypertens. 2007, 25:1620-1626.
41. Murabito J.M., White C.C., Kavousi M., Sun Y.V., Feitosa M.F., et al. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ. Cardiovasc. Genet. 2012, 5:100-112.
42. National Research Council N Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic: Interim Report 2014, National Research Council, Washington, DC.
43. Naujokas M.F., Anderson B., Ahsan H., Aposhian H.V., Graziano J.H., et al. The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem. Environ. Health Perspect. 2013, 121:295-302.
44. Nixon D.E., Mussmann G.V., Eckdahl S.J., Moyer T.P. Total arsenic in urine - palladium persulfate vs nickel as a matrix modifier for graphite-furnace atomic-absorption spectrophotometry. Clin. Chem. 1991, 37:1575-1579.
45. O'Brien E., Waeber B., Parati G., Staessen J., Myers M.G. Blood pressure measuring devices: recommendations of the European Society of Hypertension. BMJ 2001, 322:531-536.
46. Pei Q., Ma N., Zhang J., Xu W., Li Y., et al. Oxidative DNA damage of peripheral blood polymorphonuclear leukocytes, selectively induced by chronic arsenic exposure, is associated with extent of arsenic-related skin lesions. Toxicol. Appl. Pharmacol. 2013, 266:143-149.
47. Pierce B.L., Kibriya M.G., Tong L., Jasmine F., Argos M., et al. Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. PLoS Genet. 2012, 8:e1002522.
48. Porter K.E., Basu A., Hubbard A.E., Bates M.N., Kalman D., et al. Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism. Environ. Res. 2010, 110:580-587.
49. Qian Y., Liu K.J., Chen Y., Flynn D.C., Castranova V., et al. Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization. J. Biol. Chem. 2005, 280:3875-3884.
50. Rai H., Parveen F., Kumar S., Kapoor A., Sinha N. Association of endothelial nitric oxide synthase gene polymorphisms with coronary artery disease: an updated meta-analysis and systematic review. PLoS One 2014, 9:e113363.
51. Safar M.E., Levy B.I., Struijker-Boudier H. Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases. Circulation 2003, 107:2864-2869.
52. San Jose G., Fortuno A., Beloqui O., Diez J., Zalba G. NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases. Clin. Sci. (Lond.) 2008, 114:173-182.
53. Sauer H., Shah A.M., Laurindo F.R.M. Studies on Cardiovascular Disorders 2010, Humana Press, New York, (xvii, 587 pp.).
54. SeattleSNPs. (accessed 5 March 2015). http://pga.gs.washington.edu.
55. Shiue I., Hristova K. Higher urinary heavy metal, phthalate and arsenic concentrations accounted for 3-19% of the population attributable risk for high blood pressure: US NHANES, 2009-2012. Hypertens. Res. 2014, 37:1075-1081.
56. Simeonova P.P., Luster M.I. Arsenic and atherosclerosis. Toxicol. Appl. Pharmacol. 2004, 198:444-449.
57. Smith K.R., Klei L.R., Barchowsky A. Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001, 280:L442-L449.
58. Stea F., Bianchi F., Cori L., Sicari R. Cardiovascular effects of arsenic: clinical and epidemiological findings. Environ. Sci. Pollut. Res. Int. 2014, 21:244-251.
59. Sugamura K., Keaney J.F. Reactive oxygen species in cardiovascular disease. Free Radic. Biol. Med. 2011, 51:978-992.
60. Van Geen A., Cheng Z., Seddique A.A., Hoque M.A., Gelman A., et al. Reliability of a commercial kit to test groundwater for arsenic in Bangladesh. Environ. Sci. Technol. 2005, 39:299-303.
61. Vasan R.S., Larson M.G., Leip E.P., Evans J.C., O'Donnell C.J., et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N. Engl. J. Med. 2001, 345:1291-1297.
62. Wade T.J., Xia Y., Mumford J., Wu K., Le X.C., et al. Cardiovascular disease and arsenic exposure in Inner Mongolia, China: a case control study. Environ. Health 2015, 14:35.
63. WHO Guidelines for Drinking-water Quality 2011, fourth edition.
64. WHO A Global Brief on Hypertension: Silent Killer, Global Public Health Crisis 2013, World Health Organization, Geneva, Switzerland.
65. Wu F., Jasmine F., Kibriya M.G., Liu M., Wojcik O., et al. Association between arsenic exposure from drinking water and plasma levels of cardiovascular markers. Am. J. Epidemiol. 2012, 175:1252-1261.
66. Wu F., Jasmine F., Kibriya M.G., Liu M., Cheng X., et al. Interaction between arsenic exposure from drinking water and genetic susceptibility in carotid intima-media thickness in Bangladesh. Toxicol. Appl. Pharmacol. 2014, 276:195-203.
67. Wu F., Molinaro P., Chen Y. Arsenic exposure and subclinical endpoints of cardiovascular diseases. Curr. Environ. Health Rep. 2014, 1:148-162.
68. Wu F., Jasmine F., Kibriya M.G., Liu M., Cheng X., et al. Interaction between arsenic exposure from drinking water and genetic polymorphisms on cardiovascular disease in Bangladesh: a prospective case-cohort study. Environ. Health Perspect. 2015, 123(5):451-457.
69. Xu H., Li H., Liu J., Zhu D., Wang Z., et al. Meta-analysis of apolipoprotein e gene polymorphism and susceptibility of myocardial infarction. PLoS One 2014, 9:e104608.
70. Zhang C., Mao G., He S., Yang Z., Yang W., et al. Relationship between long-term exposure to low-level arsenic in drinking water and the prevalence of abnormal blood pressure. J. Hazard. Mater. 2013, 262:1154-1158.