LC-MS/MS-based quantification of cholesterol and related metabolites in dried blood for the screening of inborn errors of sterol metabolism

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 17, 2015, Pages 5227-5233

  Becker, S ^a,b   Rohnike S ^c   Empting, S ^c   Haas, D ^d   Mohnike, K ^c   Beblo, S ^b   Mutze U ^b   Husain, R A ^e   Thiery, J ^a,b   Ceglarek, U ^a,b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^e JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

7 Dehydrocholesterol; Dried blood spots; Smith Lemli Opitz syndrome; Tandem mass spectrometry

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; CHOLESTEROL; DIAGNOSIS; MASS SPECTROMETRY; METABOLISM; PATIENT TREATMENT; SPECTROMETRY;

7-DEHYDROCHOLESTEROL; DRIED BLOOD SPOTS; INTER-ASSAY VARIABILITY; PROTEIN PRECIPITATION; RETROSPECTIVE ANALYSIS; SMITH-LEMLI-OPITZ SYNDROME; TANDEM MASS SPECTROMETRIC; TANDEM MASS SPECTROMETRY;

BLOOD;

7 DEHYDROCHOLESTEROL; 7-DEHYDROCHOLESTEROL; CHOLESTA-5,8-DIEN-3 BETA-OL; CHOLESTEROL;

BLOOD; DRIED BLOOD SPOT TESTING; ECONOMICS; EVALUATION STUDY; HUMAN; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; NEWBORN; PROCEDURES; SMITH LEMLI OPITZ SYNDROME; TANDEM MASS SPECTROMETRY;

CHOLESTADIENOLS; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; DEHYDROCHOLESTEROLS; DRIED BLOOD SPOT TESTING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INFANT, NEWBORN; LIMIT OF DETECTION; SMITH-LEMLI-OPITZ SYNDROME; TANDEM MASS SPECTROMETRY;

EID: 84938327454     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-8731-1     Document Type: Article

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