Homozygous familial hypercholesterolemia. First case in Spain treated with lomitapide, an inhibitor of the synthesis of lipoproteins with apolipoprotein B;Hipercolesterolemia familiar homocigota. Primer caso en España tratado con lomitapide, un inhibidor de la síntesis de lipoproteínas con apolipoproteína B

Medicina Clinica

Volumn 145, Issue 5, 2015, Pages 229-230

  Alonso, Rodrigo ^a   Mata, Pedro ^b   Alonso Y Gregorio, Moises ^a   De Andrés, Raimundo ^a  

^a Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^b Medicina Interna   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; LIPOPROTEIN; LOMITAPIDE; BENZIMIDAZOLE DERIVATIVE; CARRIER PROTEIN; HYPOCHOLESTEROLEMIC AGENT; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN;

ENZYME INHIBITION; FAMILIAL HYPERCHOLESTEROLEMIA; HUMAN; LETTER; PROTEIN SYNTHESIS; SPAIN; ADULT; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BLOOD; BODY WEIGHT; DIET THERAPY; DRUG EFFECTS; FEMALE; HYPERLIPOPROTEINEMIA TYPE II; MULTIMODALITY CANCER THERAPY;

ADULT; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEINS B; BENZIMIDAZOLES; BODY WEIGHT; CARRIER PROTEINS; CHOLESTEROL, LDL; COMBINED MODALITY THERAPY; FEMALE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; LIPIDS;

EID: 84938264039     PISSN: 00257753     EISSN: 15788989     Source Type: Journal    
DOI: 10.1016/j.medcli.2014.11.002     Document Type: Letter

References (5)

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4. M. Cuchel, E.A. Meagher, H. du Toit Theron, D.J. Blom, A.D. Marais, R.A. Hegele, and et al. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolemia: A single-arm, open-label, phase 3 study Lancet 381 2013 40 46
5. M. Cuchel, D.J. Blom, M.R. Averna, E.A. Meagher, H.D. Theron, C.R. Sirtori, and et al. Sustained LDL-C lowering and stable hepatic fat levels in patients with homozygous familial hypercholesterolemia treated with the microsomal triglyceride transfer protein inhibitor lomitapide: Results of an ongoing long-term extension study Circulation. 128 2013 Abstract 16516