Vitamin D and tuberculosis: More effective in prevention than treatment?

International Journal of Tuberculosis and Lung Disease

Volumn 19, Issue 8, 2015, Pages 876-

  Davies, Peter D O ^a   Martineau, Adrian R ^b  

^a LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; TUBERCULOSTATIC AGENT; VITAMIN D RECEPTOR; VITAMIN D;

COHORT ANALYSIS; DISEASE PREDISPOSITION; DRUG EFFICACY; DRUG RESPONSE; EDITORIAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOMODULATION; LUNG DISEASE; MONGOLIA; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); TANZANIA; TUBERCULOSIS; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN METABOLISM; ANALOGS AND DERIVATIVES; FEMALE; MALE; TUBERCULOSIS, PULMONARY;

ANTITUBERCULAR AGENTS; FEMALE; HUMANS; MALE; TUBERCULOSIS, PULMONARY; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84938230575     PISSN: 10273719     EISSN: 18157920     Source Type: Journal    
DOI: 10.5588/ijtld.15.0506     Document Type: Editorial

References (5)

1. Davies P D. A possible link between vitamin D deficiency and impaired host defence to Mycobacterium tuberculosis. Tubercle 1985; 66: 301-306.
2. Sloan D, Mwandumba H, Kamdolozi M, et al. Vitamin D deficiency in Malawian adults with pulmonary tuberculosis: risk factors and treatment outcomes. Int J Tuberc Lung Dis 2015; 19: 000-000. [in this issue]
3. Martineau A R, Timms P M, Bothamley G H, et al. High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Lancet 2011; 377: 242-250.
4. Junaid K, Rehman A, Saeed T, JolliffeDA,Wood K, Martineau A R. Genotype-independent association between profound vitamin D deficiency and delayed sputum smear conversion in pulmonary tuberculosis. BMC Infect Dis. 2015; in revision.
5. Coussens A K, Wilkinson R J, Hanifa Y, et al. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proc Natl Acad Sci USA 2012; 109: 15 449-15 454.