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Volumn 67, Issue 8, 2015, Pages 2046-2055

Internalization of rituximab and the efficiency of B cell depletion in rheumatoid arthritis and systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CELL SURFACE PROTEIN; FC RECEPTOR IIB; OBINUTUZUMAB; OFATUMUMAB; RITUXIMAB; TOSITUMOMAB; ANTIRHEUMATIC AGENT; FC RECEPTOR; MONOCLONAL ANTIBODY;

EID: 84938071022     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39167     Document Type: Article
Times cited : (63)

References (51)
  • 1
    • 0036785351 scopus 로고    scopus 로고
    • Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion
    • Leandro MJ, Edwards JC, Cambridge G., Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion. Ann Rheum Dis 2002; 61: 883-8.
    • (2002) Ann Rheum Dis , vol.61 , pp. 883-888
    • Leandro, M.J.1    Edwards, J.C.2    Cambridge, G.3
  • 2
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab
    • Looney RJ, Anolik JH, Campbell D, Felgar RE, Young F, Arend LJ, et al., B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab. Arthritis Rheum 2004; 50: 2580-9.
    • (2004) Arthritis Rheum , vol.50 , pp. 2580-2589
    • Looney, R.J.1    Anolik, J.H.2    Campbell, D.3    Felgar, R.E.4    Young, F.5    Arend, L.J.6
  • 3
    • 79953679566 scopus 로고    scopus 로고
    • Reduced-dose rituximab in rheumatoid arthritis: Efficacy depends on degree of B cell depletion
    • Vital EM, Rawstron AC, Dass S, Henshaw K, Madden J, Emery P, et al., Reduced-dose rituximab in rheumatoid arthritis: efficacy depends on degree of B cell depletion. Arthritis Rheum 2011; 63: 603-8.
    • (2011) Arthritis Rheum , vol.63 , pp. 603-608
    • Vital, E.M.1    Rawstron, A.C.2    Dass, S.3    Henshaw, K.4    Madden, J.5    Emery, P.6
  • 5
    • 84934943192 scopus 로고    scopus 로고
    • An extra dose of rituximab improves clinical response in rheumatoid arthritis patients with initial incomplete B cell depletion: A randomised controlled trial
    • E-pub ahead of print.
    • Vital EM, Dass S, Buch MH, Rawstron AC, Emery P., An extra dose of rituximab improves clinical response in rheumatoid arthritis patients with initial incomplete B cell depletion: a randomised controlled trial. Ann Rheum Dis 2014. E-pub ahead of print.
    • (2014) Ann Rheum Dis
    • Vital, E.M.1    Dass, S.2    Buch, M.H.3    Rawstron, A.C.4    Emery, P.5
  • 6
    • 84938061404 scopus 로고    scopus 로고
    • Longer duration of B cell depletion in patients with systemic lupus erythematosus is associated with a better outcome [abstract]
    • Rodriguez-Garcia V, Sapeta Dias S, Nguyen H, Pericleous C, Isenberg DA., Longer duration of B cell depletion in patients with systemic lupus erythematosus is associated with a better outcome [abstract]. Ann Rheum Dis 2014; 73 Suppl 2: 359.
    • (2014) Ann Rheum Dis , vol.73 , pp. 359
    • Rodriguez-Garcia, V.1    Sapeta Dias, S.2    Nguyen, H.3    Pericleous, C.4    Isenberg, D.A.5
  • 8
    • 34548221347 scopus 로고    scopus 로고
    • Mechanisms of killing by anti-CD20 monoclonal antibodies
    • Glennie MJ, French RR, Cragg MS, Taylor RP., Mechanisms of killing by anti-CD20 monoclonal antibodies. Mol Immunol 2007; 44: 3823-37.
    • (2007) Mol Immunol , vol.44 , pp. 3823-3837
    • Glennie, M.J.1    French, R.R.2    Cragg, M.S.3    Taylor, R.P.4
  • 9
    • 84895448860 scopus 로고    scopus 로고
    • The 158VV Fcγ receptor 3A genotype is associated with response to rituximab in rheumatoid arthritis: Results of an Italian multicentre study
    • Quartuccio L, Fabris M, Pontarini E, Salvin S, Zabotti A, Benucci M, et al., The 158VV Fcγ receptor 3A genotype is associated with response to rituximab in rheumatoid arthritis: results of an Italian multicentre study. Ann Rheum Dis 2014; 73: 716-21.
    • (2014) Ann Rheum Dis , vol.73 , pp. 716-721
    • Quartuccio, L.1    Fabris, M.2    Pontarini, E.3    Salvin, S.4    Zabotti, A.5    Benucci, M.6
  • 10
    • 0037289807 scopus 로고    scopus 로고
    • The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus
    • Anolik JH, Campbell D, Felgar RE, Young F, Sanz I, Rosenblatt J, et al., The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus. Arthritis Rheum 2003; 48: 455-9.
    • (2003) Arthritis Rheum , vol.48 , pp. 455-459
    • Anolik, J.H.1    Campbell, D.2    Felgar, R.E.3    Young, F.4    Sanz, I.5    Rosenblatt, J.6
  • 11
    • 33947159739 scopus 로고    scopus 로고
    • Genetic linkage of FcγRIIa and FcγRIIIa and implications for their use in predicting clinical responses to CD20-directed monoclonal antibody therapy. Clin
    • Hatjiharissi E, Hansen M, Santos DD, Xu L, Leleu X, Dimmock EW, et al., Genetic linkage of FcγRIIa and FcγRIIIa and implications for their use in predicting clinical responses to CD20-directed monoclonal antibody therapy. Clin Lymphoma Myeloma 2007; 7: 286-90.
    • (2007) Lymphoma Myeloma , vol.7 , pp. 286-290
    • Hatjiharissi, E.1    Hansen, M.2    Santos, D.D.3    Xu, L.4    Leleu, X.5    Dimmock, E.W.6
  • 12
    • 0642373290 scopus 로고    scopus 로고
    • Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma
    • Weng WK, Levy R., Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol 2003; 21: 3940-7.
    • (2003) J Clin Oncol , vol.21 , pp. 3940-3947
    • Weng, W.K.1    Levy, R.2
  • 13
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene
    • Cartron G, Dacheux L, Salles G, Solal-Celigny P, Bardos P, Colombat P, et al., Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene. Blood 2002; 99: 754-8.
    • (2002) Blood , vol.99 , pp. 754-758
    • Cartron, G.1    Dacheux, L.2    Salles, G.3    Solal-Celigny, P.4    Bardos, P.5    Colombat, P.6
  • 14
    • 1642306050 scopus 로고    scopus 로고
    • Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents
    • Cragg MS, Glennie MJ., Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents. Blood 2004; 103: 2738-43.
    • (2004) Blood , vol.103 , pp. 2738-2743
    • Cragg, M.S.1    Glennie, M.J.2
  • 15
    • 84860390375 scopus 로고    scopus 로고
    • Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: A randomised, double-blind, placebo-controlled clinical trial
    • Taylor PC, Quattrocchi E, Mallett S, Kurrasch R, Petersen J, Chang DJ., Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: a randomised, double-blind, placebo-controlled clinical trial. Ann Rheum Dis 2011; 70: 2119-25.
    • (2011) Ann Rheum Dis , vol.70 , pp. 2119-2125
    • Taylor, P.C.1    Quattrocchi, E.2    Mallett, S.3    Kurrasch, R.4    Petersen, J.5    Chang, D.J.6
  • 16
    • 84863012323 scopus 로고    scopus 로고
    • Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: Results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial
    • Tak PP, Mease PJ, Genovese MC, Kremer J, Haraoui B, Tanaka Y, et al., Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial. Arthritis Rheum 2012; 64: 360-70.
    • (2012) Arthritis Rheum , vol.64 , pp. 360-370
    • Tak, P.P.1    Mease, P.J.2    Genovese, M.C.3    Kremer, J.4    Haraoui, B.5    Tanaka, Y.6
  • 17
    • 58149162030 scopus 로고    scopus 로고
    • Type II (tositumomab) anti-CD20 monoclonal antibody out performs type i (rituximab-like) reagents in B-cell depletion regardless of complement activation
    • Beers SA, Chan CH, James S, French RR, Attfield KE, Brennan CM, et al., Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation. Blood 2008; 112: 4170-7.
    • (2008) Blood , vol.112 , pp. 4170-4177
    • Beers, S.A.1    Chan, C.H.2    James, S.3    French, R.R.4    Attfield, K.E.5    Brennan, C.M.6
  • 18
    • 79953183947 scopus 로고    scopus 로고
    • Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab
    • Bologna L, Gotti E, Manganini M, Rambaldi A, Intermesoli T, Introna M, et al., Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab. J Immunol 2011; 186: 3762-9.
    • (2011) J Immunol , vol.186 , pp. 3762-3769
    • Bologna, L.1    Gotti, E.2    Manganini, M.3    Rambaldi, A.4    Intermesoli, T.5    Introna, M.6
  • 19
  • 20
    • 80052533015 scopus 로고    scopus 로고
    • Fcγ receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy
    • Lim SH, Vaughan AT, Ashton-Key M, Williams EL, Dixon SV, Chan HT, et al., Fcγ receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy. Blood 2011; 118: 2530-40.
    • (2011) Blood , vol.118 , pp. 2530-2540
    • Lim, S.H.1    Vaughan, A.T.2    Ashton-Key, M.3    Williams, E.L.4    Dixon, S.V.5    Chan, H.T.6
  • 21
    • 84925379432 scopus 로고    scopus 로고
    • Antigenic modulation limits the effector cell mechanisms employed by type i anti-CD20 monoclonal antibodies
    • Tipton TR, Roghanian A, Oldham RJ, Carter MJ, Cox KL, Mockridge CI, et al., Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies. Blood 2015; 125: 1901-9.
    • (2015) Blood , vol.125 , pp. 1901-1909
    • Tipton, T.R.1    Roghanian, A.2    Oldham, R.J.3    Carter, M.J.4    Cox, K.L.5    Mockridge, C.I.6
  • 22
    • 77954679392 scopus 로고    scopus 로고
    • Antigenic modulation limits the efficacy of anti-CD20 antibodies: Implications for antibody selection
    • Beers SA, French RR, Chan HT, Lim SH, Jarrett TC, Vidal RM, et al., Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection. Blood 2010; 115: 5191-201.
    • (2010) Blood , vol.115 , pp. 5191-5201
    • Beers, S.A.1    French, R.R.2    Chan, H.T.3    Lim, S.H.4    Jarrett, T.C.5    Vidal, R.M.6
  • 23
    • 84964315758 scopus 로고    scopus 로고
    • Expression of the inhibitory Fcγ receptor IIB (FCGR2B, CD32B) on follicular lymphoma cells lowers the response rate to rituximab monotherapy (SAKK 35/98)
    • Lee CS, Ashton-Key M, Cogliatti S, Rondeau S, Schmitz SF, Ghielmini, et al., Expression of the inhibitory Fcγ receptor IIB (FCGR2B, CD32B) on follicular lymphoma cells lowers the response rate to rituximab monotherapy (SAKK 35/98). Br J Haematol 2015; 168: 139-59.
    • (2015) Br J Haematol , vol.168 , pp. 139-159
    • Lee, C.S.1    Ashton-Key, M.2    Cogliatti, S.3    Rondeau, S.4    Schmitz, S.F.5    Ghielmini6
  • 24
    • 84894078151 scopus 로고    scopus 로고
    • Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity
    • Vaughan AT, Iriyama C, Beers SA, Chan CH, Lim SH, Williams EL, et al., Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity. Blood 2014; 123: 669-77.
    • (2014) Blood , vol.123 , pp. 669-677
    • Vaughan, A.T.1    Iriyama, C.2    Beers, S.A.3    Chan, C.H.4    Lim, S.H.5    Williams, E.L.6
  • 25
    • 34249664979 scopus 로고    scopus 로고
    • Preclinical and clinical evaluation of epratuzumab (anti-CD22 IgG) in B-cell malignancies
    • Leonard JP, Goldenberg DM., Preclinical and clinical evaluation of epratuzumab (anti-CD22 IgG) in B-cell malignancies. Oncogene 2007; 26: 3704-13.
    • (2007) Oncogene , vol.26 , pp. 3704-3713
    • Leonard, J.P.1    Goldenberg, D.M.2
  • 27
    • 33748778482 scopus 로고    scopus 로고
    • Epratuzumab, a CD22-targeting recombinant humanized antibody with a different mode of action from rituximab
    • Carnahan J, Stein R, Qu Z, Hess K, Cesano A, Hansen HJ, et al., Epratuzumab, a CD22-targeting recombinant humanized antibody with a different mode of action from rituximab. Mol Immunol 2007; 44: 1331-41.
    • (2007) Mol Immunol , vol.44 , pp. 1331-1341
    • Carnahan, J.1    Stein, R.2    Qu, Z.3    Hess, K.4    Cesano, A.5    Hansen, H.J.6
  • 28
    • 84889657510 scopus 로고    scopus 로고
    • Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: Results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study
    • Wallace DJ, Kalunian K, Petri MA, Strand V, Houssiau FA, Pike M, et al., Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study. Ann Rheum Dis 2014; 73: 183-90.
    • (2014) Ann Rheum Dis , vol.73 , pp. 183-190
    • Wallace, D.J.1    Kalunian, K.2    Petri, M.A.3    Strand, V.4    Houssiau, F.A.5    Pike, M.6
  • 29
    • 41849121941 scopus 로고    scopus 로고
    • Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls
    • Jacobi AM, Goldenberg DM, Hiepe F, Radbruch A, Burmester GR, Dorner T., Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls. Ann Rheum Dis 2008; 67: 450-7.
    • (2008) Ann Rheum Dis , vol.67 , pp. 450-457
    • Jacobi, A.M.1    Goldenberg, D.M.2    Hiepe, F.3    Radbruch, A.4    Burmester, G.R.5    Dorner, T.6
  • 31
    • 77951561987 scopus 로고    scopus 로고
    • Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity
    • Mossner E, Brunker P, Moser S, Puntener U, Schmidt C, Herter S, et al., Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. Blood 2010; 115: 4393-402.
    • (2010) Blood , vol.115 , pp. 4393-4402
    • Mossner, E.1    Brunker, P.2    Moser, S.3    Puntener, U.4    Schmidt, C.5    Herter, S.6
  • 32
    • 0035760902 scopus 로고    scopus 로고
    • CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: Further regulation by CD55 and CD59
    • Golay J, Lazzari M, Facchinetti V, Bernasconi S, Borleri G, Barbui T, et al., CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59. Blood 2001; 98: 3383-9.
    • (2001) Blood , vol.98 , pp. 3383-3389
    • Golay, J.1    Lazzari, M.2    Facchinetti, V.3    Bernasconi, S.4    Borleri, G.5    Barbui, T.6
  • 33
    • 33847375266 scopus 로고    scopus 로고
    • Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus
    • Su K, Yang H, Li X, Li X, Gibson AW, Cafardi JM, et al., Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol 2007; 178: 3272-280.
    • (2007) J Immunol , vol.178 , pp. 3272-3280
    • Su, K.1    Yang, H.2    Li, X.3    Li, X.4    Gibson, A.W.5    Cafardi, J.M.6
  • 35
    • 33745924969 scopus 로고    scopus 로고
    • B cell antigen receptor signaling and internalization are mutually exclusive events
    • Hou P, Araujo E, Zhao T, Zhang M, Massenburg D, Veselits M, et al., B cell antigen receptor signaling and internalization are mutually exclusive events. PLoS Biol 2006; 4: e200.
    • (2006) PLoS Biol , vol.4 , pp. e200
    • Hou, P.1    Araujo, E.2    Zhao, T.3    Zhang, M.4    Massenburg, D.5    Veselits, M.6
  • 36
    • 0035093233 scopus 로고    scopus 로고
    • Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes
    • Edwards JC, Cambridge G., Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes. Rheumatology (Oxford) 2001; 40: 205-11.
    • (2001) Rheumatology (Oxford) , vol.40 , pp. 205-211
    • Edwards, J.C.1    Cambridge, G.2
  • 39
    • 67650606765 scopus 로고    scopus 로고
    • Rituximab in systemic lupus erythematosus: A systematic review of off-label use in 188 cases
    • Ramos-Casals M, Soto MJ, Cuadrado MJ, Khamashta MA., Rituximab in systemic lupus erythematosus: a systematic review of off-label use in 188 cases. Lupus 2009; 18: 767-76.
    • (2009) Lupus , vol.18 , pp. 767-776
    • Ramos-Casals, M.1    Soto, M.J.2    Cuadrado, M.J.3    Khamashta, M.A.4
  • 40
    • 74849131972 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
    • Merrill JT, Neuwelt CM, Wallace DJ, Shanahan JC, Latinis KM, Oates JC, et al., Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum 2010; 62: 222-33.
    • (2010) Arthritis Rheum , vol.62 , pp. 222-233
    • Merrill, J.T.1    Neuwelt, C.M.2    Wallace, D.J.3    Shanahan, J.C.4    Latinis, K.M.5    Oates, J.C.6
  • 41
    • 84866184129 scopus 로고    scopus 로고
    • The LUNAR Investigator Group. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The Lupus Nephritis Assessment with Rituximab study
    • Rovin BH, Furie R, Latinis K, Looney RJ, Fervenza FC, Sanchez-Guerrero J, et al., for the LUNAR Investigator Group. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum 2012; 64: 1215-26.
    • (2012) Arthritis Rheum , vol.64 , pp. 1215-1226
    • Rovin, B.H.1    Furie, R.2    Latinis, K.3    Looney, R.J.4    Fervenza, F.C.5    Sanchez-Guerrero, J.6
  • 42
    • 84873599778 scopus 로고    scopus 로고
    • B cell depletion in SLE: Clinical and trial experience with rituximab and ocrelizumab and implications for study design
    • Reddy V, Jayne D, Close D, Isenberg D., B cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design. Arthritis Res Ther 2013; 15 Suppl 1: S4.
    • (2013) Arthritis Res Ther , vol.15 , pp. S4
    • Reddy, V.1    Jayne, D.2    Close, D.3    Isenberg, D.4
  • 43
    • 54949129325 scopus 로고    scopus 로고
    • Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis
    • Dass S, Rawstron AC, Vital EM, Henshaw K, McGonagle D, Emery P., Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis. Arthritis Rheum 2008; 58: 2993-9.
    • (2008) Arthritis Rheum , vol.58 , pp. 2993-2999
    • Dass, S.1    Rawstron, A.C.2    Vital, E.M.3    Henshaw, K.4    McGonagle, D.5    Emery, P.6
  • 44
    • 84876740605 scopus 로고    scopus 로고
    • Serum rituximab levels and efficiency of B cell depletion: Differences between patients with rheumatoid arthritis and systemic lupus erythematosus
    • Reddy V, Croca S, Gerona D, De La Torre I, Isenberg D, McDonald V, et al., Serum rituximab levels and efficiency of B cell depletion: differences between patients with rheumatoid arthritis and systemic lupus erythematosus. Rheumatology (Oxford) 2013; 52: 951-2.
    • (2013) Rheumatology (Oxford) , vol.52 , pp. 951-952
    • Reddy, V.1    Croca, S.2    Gerona, D.3    De La Torre, I.4    Isenberg, D.5    McDonald, V.6
  • 45
    • 56749153905 scopus 로고    scopus 로고
    • Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus
    • Albert D, Dunham J, Khan S, Stansberry J, Kolasinski S, Tsai D, et al., Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus. Ann Rheum Dis 2008; 67: 1724-31.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1724-1731
    • Albert, D.1    Dunham, J.2    Khan, S.3    Stansberry, J.4    Kolasinski, S.5    Tsai, D.6
  • 47
    • 0020620324 scopus 로고
    • Natural killer cell in systemic lupus erythematosus: Defects in effector lytic activity and response to interferon and interferon inducers
    • Sibbitt WL Jr, Mathews PM, Bankhurst AD., Natural killer cell in systemic lupus erythematosus: defects in effector lytic activity and response to interferon and interferon inducers. J Clin Invest 1983; 71: 1230-9.
    • (1983) J Clin Invest , vol.71 , pp. 1230-1239
    • Sibbitt, Jr.W.L.1    Mathews, P.M.2    Bankhurst, A.D.3
  • 48
    • 84903184153 scopus 로고    scopus 로고
    • Complement and systemic lupus erythematosus
    • Walport MJ., Complement and systemic lupus erythematosus. Arthritis Res 2002; 4 Suppl 3: S279-93.
    • (2002) Arthritis Res , vol.4 , pp. S279-S293
    • Walport, M.J.1
  • 49
    • 84938110728 scopus 로고    scopus 로고
    • US Food and DrugAdministration. Gazyva (obinutuzumab). URL: http://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm373263.htm.
    • Gazyva (Obinutuzumab)
  • 50
    • 84879502096 scopus 로고    scopus 로고
    • Efficacy and safety of epratuzumab in patients with moderate/severe flaring systemic lupus erythematosus: Results from two randomized, double-blind, placebo-controlled, multicentre studies (ALLEVIATE) and follow-up
    • Wallace DJ, Gordon C, Strand V, Hobbs K, Petri M, Kalunian K, et al., Efficacy and safety of epratuzumab in patients with moderate/severe flaring systemic lupus erythematosus: results from two randomized, double-blind, placebo-controlled, multicentre studies (ALLEVIATE) and follow-up. Rheumatology (Oxford) 2013; 52: 1313-22.
    • (2013) Rheumatology (Oxford) , vol.52 , pp. 1313-1322
    • Wallace, D.J.1    Gordon, C.2    Strand, V.3    Hobbs, K.4    Petri, M.5    Kalunian, K.6
  • 51
    • 0029025026 scopus 로고
    • Constitutive endocytosis and degradation of CD22 by human B cells
    • Shan D, Press OW., Constitutive endocytosis and degradation of CD22 by human B cells. J Immunol 1995; 154: 4466-75.
    • (1995) J Immunol , vol.154 , pp. 4466-4475
    • Shan, D.1    Press, O.W.2


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