A Bright Future for Evolutionary Methods in Drug Design

ChemMedChem

Volumn 10, Issue 8, 2015, Pages 1296-1300

  Le, Tu C ^a   Winkler, David A ^a,b,c  

^a CSIRO   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

chemical space; drug design; drug like space; evolutionary algorithms; genetic algorithms

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DNA POLYMERASE;

BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; COMBINATORIAL LIBRARY; DRUG DESIGN; EVOLUTIONARY ALGORITHM; GENETIC ALGORITHM; HIGH THROUGHPUT SCREENING; MEDICINAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; ALGORITHM; DRUG DEVELOPMENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

ALGORITHMS; DRUG DESIGN; DRUG DISCOVERY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SELEX APTAMER TECHNIQUE;

EID: 84937970694     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201500161     Document Type: Review

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