Clinical characteristics of children and young adults with co-occurring autism spectrum disorder and epilepsy

Epilepsy and Behavior

Volumn 47, Issue , 2015, Pages 183-190

  El Achkar, Christelle M ^a   Spence, Sarah J ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Autism; Autism spectrum disorder; Comorbidity; EEG; Epilepsy; Seizure

Indexed keywords

AUTISM; CLINICAL FEATURE; COMORBIDITY; DISEASE ASSOCIATION; DISEASE SEVERITY; DISEASE SURVEILLANCE; ELECTROENCEPHALOGRAPHY; EPILEPSY; FAMILY HISTORY; HUMAN; INFANTILE SPASM; INTELLECTUAL IMPAIRMENT; MORTALITY; ONSET AGE; PROGNOSIS; REMISSION; REVIEW; RISK FACTOR; SCREENING TEST; SEIZURE; SEX DIFFERENCE; TREATMENT PLANNING; AUTISM SPECTRUM DISORDER; CHILD; COMPLICATION; PSYCHOLOGY; YOUNG ADULT;

AUTISM SPECTRUM DISORDER; CHILD; EPILEPSY; HUMANS; YOUNG ADULT;

EID: 84937969028     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2014.12.022     Document Type: Review

References (63)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 2013, American Psychiatric Association, Arlington, VA. 5th ed.
2. Amiet C., Gourfinkel-An I., Laurent C., Carayol J., Genin B., Leguern E., et al. Epilepsy in simplex autism pedigrees is much lower than the rate in multiplex autism pedigrees. Biol Psychiatry 2013, 74:e3-e4.
3. Hughes J.R., Melyn M. EEG and seizures in autistic children and adolescents: further findings with therapeutic implications. Clin EEG Neurosci 2005, 36:15-20.
4. Jokiranta E., Sourander A., Suominen A., Timonen-Soivio L., Brown A.S., Sillanpaa M. Epilepsy among children and adolescents with autism spectrum disorders: a population-based study. J Autism Dev Disord 2014, 44:2547-2557.
5. Kohane I.S., McMurry A., Weber G., MacFadden D., Rappaport L., Kunkel L., et al. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One 2012, 7:e33224.
6. Viscidi E.W., Triche E.W., Pescosolido M.F., McLean R.L., Joseph R.M., Spence S.J., et al. Clinical characteristics of children with autism spectrum disorder and co-occurring epilepsy. PLoS One 2013, 8:e67797.
7. Suren P., Bakken I.J., Aase H., Chin R., Gunnes N., Lie K.K., et al. Autism spectrum disorder, ADHD, epilepsy, and cerebral palsy in Norwegian children. Pediatrics 2012, 130:e152-e158.
8. Mouridsen S.E., Rich B., Isager T. Epilepsy and other central nervous system diseases in atypical autism: a case control study. J Neural Transm 2011, 118:621-627.
9. Spence S.J., Schneider M.T. The role of epilepsy and epileptiform EEGs in autism spectrum disorders. Pediatr Res 2009, 65:599-606.
10. Yasuhara A. Correlation between EEG abnormalities and symptoms of autism spectrum disorder (ASD). Brain Dev 2010, 32:791-798.
11. Amiet C., Gourfinkel-An I., Bouzamondo A., Tordjman S., Baulac M., Lechat P., et al. Epilepsy in autism is associated with intellectual disability and gender: evidence from a meta-analysis. Biol Psychiatry 2008, 64:577-582.
12. Woolfenden S., Sarkozy V., Ridley G., Coory M., Williams K. A systematic review of two outcomes in autism spectrum disorder - epilepsy and mortality. Dev Med Child Neurol 2012, 54:306-312.
13. Danielsson S., Gillberg I.C., Billstedt E., Gillberg C., Olsson I. Epilepsy in young adults with autism: a prospective population-based follow-up study of 120 individuals diagnosed in childhood. Epilepsia 2005, 46:918-923.
14. Hara H. Autism and epilepsy: a retrospective follow-up study. Brain Dev 2007, 29:486-490.
15. Pavone P., Incorpora G., Fiumara A., Parano E., Trifiletti R.R., Ruggieri M. Epilepsy is not a prominent feature of primary autism. Neuropediatrics 2004, 35:207-210.
16. Parmeggiani A., Barcia G., Posar A., Raimondi E., Santucci M., Scaduto M.C. Epilepsy and EEG paroxysmal abnormalities in autism spectrum disorders. Brain Dev 2010, 32:783-789.
17. Barger B.D., Campbell J.M., McDonough J.D. Prevalence and onset of regression within autism spectrum disorders: a meta-analytic review. J Autism Dev Disord 2013, 43:817-828.
18. Tuchman R.F., Rapin I. Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. Pediatrics 1997, 99:560-566.
19. Mulligan C.K., Trauner D.A. Incidence and behavioral correlates of epileptiform abnormalities in autism spectrum disorders. J Autism Dev Disord 2014, 44:452-458.
20. Rossi P.G., Parmeggiani A., Bach V., Santucci M., Visconti P. EEG features and epilepsy in patients with autism. Brain Dev 1995, 17:169-174.
21. Bolton P.F., Carcani-Rathwell I., Hutton J., Goode S., Howlin P., Rutter M. Epilepsy in autism: features and correlates. Br J Psychiatry 2011, 198:289-294.
22. Parmeggiani A., Posar A., Antolini C., Scaduto M.C., Santucci M., Giovanardi-Rossi P. Epilepsy in patients with pervasive developmental disorder not otherwise specified. J Child Neurol 2007, 22:1198-1203.
23. Canitano R., Luchetti A., Zappella M. Epilepsy, electroencephalographic abnormalities, and regression in children with autism. J Child Neurol 2005, 20:27-31.
24. Hrdlicka M., Komarek V., Propper L., Kulisek R., Zumrova A., Faladova L., et al. Not EEG abnormalities but epilepsy is associated with autistic regression and mental functioning in childhood autism. Eur Child Adolesc Psychiatry 2004, 13:209-213.
25. Kobayashi R., Murata T. Setback phenomenon in autism and long-term prognosis. Acta Psychiatr Scand 1998, 98:296-303.
26. Giannotti F., Cortesi F., Cerquiglini A., Miraglia D., Vagnoni C., Sebastiani T., et al. An investigation of sleep characteristics, EEG abnormalities and epilepsy in developmentally regressed and non-regressed children with autism. J Autism Dev Disord 2008, 38:1888-1897.
27. Sansa G., Carlson C., Doyle W., Weiner H.L., Bluvstein J., Barr W., et al. Medically refractory epilepsy in autism. Epilepsia 2011, 52:1071-1075.
28. Amiet C., Gourfinkel-An I., Laurent C., Bodeau N., Genin B., Leguern E., et al. Does epilepsy in multiplex autism pedigrees define a different subgroup in terms of clinical characteristics and genetic risk?. Mol Autism 2013, 4:47.
29. Ekinci O., Arman A.R., Isik U., Bez Y., Berkem M. EEG abnormalities and epilepsy in autistic spectrum disorders: clinical and familial correlates. Epilepsy Behav 2010, 17:178-182.
30. Turk J., Bax M., Williams C., Amin P., Eriksson M., Gillberg C. Autism spectrum disorder in children with and without epilepsy: impact on social functioning and communication. Acta Paediatr 2009, 98:675-681.
31. Ming X., Brimacombe M., Wagner G.C. Prevalence of motor impairment in autism spectrum disorders. Brain Dev 2007, 29:565-570.
32. Deykin E.Y., MacMahon B. The incidence of seizures among children with autistic symptoms. Am J Psychiatry 1979, 136:1310-1312.
33. Volkmar F.R., Nelson D.S. Seizure disorders in autism. J Am Acad Child Adolesc Psychiatry 1990, 29:127-129.
34. Kim H.L., Donnelly J.H., Tournay A.E., Book T.M., Filipek P. Absence of seizures despite high prevalence of epileptiform EEG abnormalities in children with autism monitored in a tertiary care center. Epilepsia 2006, 47:394-398.
35. Chez M.G., Chang M., Krasne V., Coughlan C., Kominsky M., Schwartz A. Frequency of epileptiform EEG abnormalities in a sequential screening of autistic patients with no known clinical epilepsy from 1996 to 2005. Epilepsy Behav 2006, 8:267-271.
36. Nass R., Gross A., Devinsky O. Autism and autistic epileptiform regression with occipital spikes. Dev Med Child Neurol 1998, 40:453-458.
37. Tuchman R.F., Rapin I., Shinnar S. Autistic and dysphasic children II: epilepsy. Pediatrics 1991, 88:1219-1225.
38. Giovanardi Rossi P., Posar A., Parmeggiani A. Epilepsy in adolescents and young adults with autistic disorder. Brain Dev 2000, 22:102-106.
39. Lewine J.D., Andrews R., Chez M., Patil A.A., Devinsky O., Smith M., et al. Magnetoencephalographic patterns of epileptiform activity in children with regressive autism spectrum disorders. Pediatrics 1999, 104:405-418.
40. Shinnar S., Rapin I., Arnold S., Tuchman R.F., Shulman L., Ballaban-Gil K., et al. Language regression in childhood. Pediatr Neurol 2001, 24:183-189.
41. Tuchman R., Rapin I. Epilepsy in autism. Lancet Neurol 2002, 1:352-358.
42. Viscidi E.W., Johnson A.L., Spence S.J., Buka S.L., Morrow E.M., Triche E.W. The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder. Autism 2013, 18:996-1006.
43. Cuccaro M.L., Tuchman R.F., Hamilton K.L., Wright H.H., Abramson R.K., Haines J.L., et al. Exploring the relationship between autism spectrum disorder and epilepsy using latent class cluster analysis. J Autism Dev Disord 2012, 42:1630-1641.
44. Kagan-Kushnir T., Roberts S.W., Snead O.C. Screening electroencephalograms in autism spectrum disorders: evidence-based guideline. J Child Neurol 2005, 20:197-206.
45. Filipek P.A., Accardo P.J., Ashwal S., Baranek G.T., Cook E.H., Dawson G., et al. Practice parameter: screening and diagnosis of autism: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society. Neurology 2000, 55:468-479.
46. Eriksson M.A., Westerlund J., Hedvall A., Amark P., Gillberg C., Fernell E. Medical conditions affect the outcome of early intervention in preschool children with autism spectrum disorders. Eur Child Adolesc Psychiatry 2013, 22:23-33.
47. Pickett J., Xiu E., Tuchman R., Dawson G., Lajonchere C. Mortality in individuals with autism, with and without epilepsy. J Child Neurol 2011, 26:932-939.
48. Reilly C., Atkinson P., Das K.B., Chin R.F., Aylett S.E., Burch V., et al. Neurobehavioral comorbidities in children with active epilepsy: a population-based study. Pediatrics 2014, 133:e1586-e1593.
49. Matsuo M., Maeda T., Sasaki K., Ishii K., Hamasaki Y. Frequent association of autism spectrum disorder in patients with childhood onset epilepsy. Brain Dev 2010, 32:759-763.
50. Berg A.T., Plioplys S., Tuchman R. Risk and correlates of autism spectrum disorder in children with epilepsy: a community-based study. J Child Neurol 2011, 26:540-547.
51. Rai D., Kerr M.P., McManus S., Jordanova V., Lewis G., Brugha T.S. Epilepsy and psychiatric comorbidity: a nationally representative population-based study. Epilepsia 2012, 53:1095-1103.
52. van Eeghen A.M., Pulsifer M.B., Merker V.L., Neumeyer A.M., van Eeghen E.E., Thibert R.L., et al. Understanding relationships between autism, intelligence, and epilepsy: a cross-disorder approach. Dev Med Child Neurol 2013, 55(2):146-153.
53. Li B.M., Liu X.R., Yi Y.H., Deng Y.H., Su T., Zou X., et al. Autism in Dravet syndrome: prevalence, features, and relationship to the clinical characteristics of epilepsy and mental retardation. Epilepsy Behav 2011, 21:291-295.
54. van Harssel J.J., Weckhuysen S., van Kempen M.J., Hardies K., Verbeek, de Kovel C.G., et al. Clinical and genetic aspects of PCDH19-related epilepsy syndromes and the possible role of PCDH19 mutations in males with autism spectrum disorders. Neurogenetics 2013, 14:23-34.
55. Pavone P., Striano P., Falsaperla R., Pavone L., Ruggieri M. Infantile spasms syndrome, West syndrome and related phenotypes: what we know in 2013. Brain Dev 2014, 36:739-751.
56. Saemundsen E., Ludvigsson P., Rafnsson V. Risk of autism spectrum disorders after infantile spasms: a population-based study nested in a cohort with seizures in the first year of life. Epilepsia 2008, 49:1865-1870.
57. Clarke D.F., Roberts W., Daraksan M., Dupuis A., McCabe J., Wood H., et al. The prevalence of autistic spectrum disorder in children surveyed in a tertiary care epilepsy clinic. Epilepsia 2005, 46:1970-1977.
58. Fisher B., Dezort C., Nordli D.R., Berg A.T. Routine developmental and autism screening in an epilepsy care setting. Epilepsy Behav 2012, 24:488-492.
59. Eom S., Fisher B., Dezort C., Berg A.T. Routine developmental, autism, behavioral, and psychological screening in epilepsy care settings. Dev Med Child Neurol 2014, 56:1100-1105.
60. Lord C., Rutter M., Le Couteur A. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994, 24:659-685.
61. Wing L. Diagnostic Interview for Social and Communication Disorders 2006, Centre for Social and Communication Disorders, Bromley, UK. 11th ed.
62. Lord C., Risi S., Lambrecht L., Cook E.H., Leventhal B.L., DiLavore PC, et al. The Autism Diagnostic Observation Schedule - Generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord 2000, 30:205-223.
63. Lord C., Rutter M., Dilavore P.C., Risi S., Gotham K., Bishop S.L. The Autism Diagnostic Observation Schedule 2nd Edition (ADOS-2) 2012, WPS Publishing, Los Angeles, CA.