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Volumn 93, Issue 8, 2015, Pages 891-904

Kidney injury is independent of endothelial HIF-1α

Author keywords

Fibrosis; Hypoxia response; Ischemia; Oxygen; Transcription factor

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 84937968550     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-015-1264-4     Document Type: Article
Times cited : (20)

References (43)
  • 1
    • 84870023241 scopus 로고    scopus 로고
    • USRDS 2013 Annual Data Report: Atlas of End-Stage Renal Disease in the United States
    • National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
    • U.S. Renal Data System (2013) USRDS 2013 Annual Data Report: Atlas of End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
    • (2013) National Institutes of Health
  • 2
    • 0025697093 scopus 로고
    • Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex
    • COI: 1:STN:280:DyaK3M%2FotlShtQ%3D%3D, PID: 2260684
    • Schurek HJ, Jost U, Baumgartl H, Bertram H, Heckmann U (1990) Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex. Am J Physiol 259:F910–F915
    • (1990) Am J Physiol , vol.259 , pp. F910-F915
    • Schurek, H.J.1    Jost, U.2    Baumgartl, H.3    Bertram, H.4    Heckmann, U.5
  • 3
    • 51849094304 scopus 로고    scopus 로고
    • Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics
    • COI: 1:CAS:528:DC%2BD1cXhtFWhtrvE, PID: 18633339
    • Fine LG, Norman JT (2008) Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics. Kidney Int 74:867–872
    • (2008) Kidney Int , vol.74 , pp. 867-872
    • Fine, L.G.1    Norman, J.T.2
  • 4
    • 0036189846 scopus 로고    scopus 로고
    • Nitric oxide in acute renal failure: NOS versus NOS
    • COI: 1:CAS:528:DC%2BD38Xit1agtbc%3D, PID: 11849438
    • Goligorsky MS, Brodsky SV, Noiri E (2002) Nitric oxide in acute renal failure: NOS versus NOS. Kidney Int 61:855–861
    • (2002) Kidney Int , vol.61 , pp. 855-861
    • Goligorsky, M.S.1    Brodsky, S.V.2    Noiri, E.3
  • 5
    • 84862004419 scopus 로고    scopus 로고
    • Effects of nitric oxide on renal interstitial fibrosis in rats with unilateral ureteral obstruction
    • COI: 1:CAS:528:DC%2BC38XntlSisL8%3D, PID: 22572614
    • Sun D, Wang Y, Liu C, Zhou X, Li X, Xiao A (2012) Effects of nitric oxide on renal interstitial fibrosis in rats with unilateral ureteral obstruction. Life Sci 90:900–909
    • (2012) Life Sci , vol.90 , pp. 900-909
    • Sun, D.1    Wang, Y.2    Liu, C.3    Zhou, X.4    Li, X.5    Xiao, A.6
  • 8
    • 40949115368 scopus 로고    scopus 로고
    • Biology of HIF-1alpha
    • COI: 1:CAS:528:DC%2BD1cXjtl2jurc%3D, PID: 18259201
    • Weidemann A, Johnson RS (2008) Biology of HIF-1alpha. Cell Death Differ 15:621–627
    • (2008) Cell Death Differ , vol.15 , pp. 621-627
    • Weidemann, A.1    Johnson, R.S.2
  • 9
    • 44749093281 scopus 로고    scopus 로고
    • The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors
    • COI: 1:CAS:528:DC%2BD1cXnt1Omurs%3D, PID: 18420194
    • Warnecke C, Weidemann A, Volke M, Schietke R, Wu X, Knaup KX, Hackenbeck T, Bernhardt W, Willam C, Eckardt KU et al (2008) The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors. Exp Cell Res 314:2016–2027
    • (2008) Exp Cell Res , vol.314 , pp. 2016-2027
    • Warnecke, C.1    Weidemann, A.2    Volke, M.3    Schietke, R.4    Wu, X.5    Knaup, K.X.6    Hackenbeck, T.7    Bernhardt, W.8    Willam, C.9    Eckardt, K.U.10
  • 10
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • COI: 1:CAS:528:DyaK2sXlslejsg%3D%3D, PID: 9000051
    • Tian H, McKnight SL, Russell DW (1997) Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11:72–82
    • (1997) Genes Dev , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 12
    • 67651098992 scopus 로고    scopus 로고
    • Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis
    • COI: 1:CAS:528:DC%2BD1MXovVKls7s%3D, PID: 19439736
    • Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B (2009) Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Blood 114:469–477
    • (2009) Blood , vol.114 , pp. 469-477
    • Skuli, N.1    Liu, L.2    Runge, A.3    Wang, T.4    Yuan, L.5    Patel, S.6    Iruela-Arispe, L.7    Simon, M.C.8    Keith, B.9
  • 14
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • COI: 1:CAS:528:DyaK1cXjvFejur0%3D, PID: 9606183
    • Ryan HE, Lo J, Johnson RS (1998) HIF-1 alpha is required for solid tumor formation and embryonic vascularization. Embo J 17:3005–3015
    • (1998) Embo J , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 15
    • 84862991047 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
    • COI: 1:CAS:528:DC%2BC38XhtFWgt7nO, PID: 22699503
    • Sarkar K, Cai Z, Gupta R, Parajuli N, Fox-Talbot K, Darshan MS, Gonzalez FJ, Semenza GL (2012) Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning. Proc Natl Acad Sci U S A 109:10504–10509
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 10504-10509
    • Sarkar, K.1    Cai, Z.2    Gupta, R.3    Parajuli, N.4    Fox-Talbot, K.5    Darshan, M.S.6    Gonzalez, F.J.7    Semenza, G.L.8
  • 16
    • 84859469406 scopus 로고    scopus 로고
    • Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-beta signaling
    • COI: 1:CAS:528:DC%2BC38XlslCrtbo%3D, PID: 22403061
    • Wei H, Bedja D, Koitabashi N, Xing D, Chen J, Fox-Talbot K, Rouf R, Chen S, Steenbergen C, Harmon JW et al (2012) Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-beta signaling. Proc Natl Acad Sci U S A 109:E841–E850
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E841-E850
    • Wei, H.1    Bedja, D.2    Koitabashi, N.3    Xing, D.4    Chen, J.5    Fox-Talbot, K.6    Rouf, R.7    Chen, S.8    Steenbergen, C.9    Harmon, J.W.10
  • 17
    • 84867912497 scopus 로고    scopus 로고
    • Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1alpha-dependent function
    • COI: 1:CAS:528:DC%2BC38XhvVSltLvO, PID: 23047702
    • Huang Y, Lei L, Liu D, Jovin I, Russell R, Johnson RS, Di Lorenzo A, Giordano FJ (2012) Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1alpha-dependent function. Proc Natl Acad Sci U S A 109:17478–17483
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 17478-17483
    • Huang, Y.1    Lei, L.2    Liu, D.3    Jovin, I.4    Russell, R.5    Johnson, R.S.6    Di Lorenzo, A.7    Giordano, F.J.8
  • 18
    • 0035159670 scopus 로고    scopus 로고
    • HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
    • COI: 1:CAS:528:DC%2BD3MXoslSisbs%3D, PID: 11689469
    • Stroka DM, Burkhardt T, Desbaillets I, Wenger RH, Neil DA, Bauer C, Gassmann M, Candinas D (2001) HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 15:2445–2453
    • (2001) FASEB J , vol.15 , pp. 2445-2453
    • Stroka, D.M.1    Burkhardt, T.2    Desbaillets, I.3    Wenger, R.H.4    Neil, D.A.5    Bauer, C.6    Gassmann, M.7    Candinas, D.8
  • 20
    • 84880948836 scopus 로고    scopus 로고
    • Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration
    • COI: 1:CAS:528:DC%2BC3sXhtFChtbjM, PID: 23871589
    • Nolan DJ, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding BS, Schachterle W, Liu Y, Rosenwaks Z et al (2013) Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Dev Cell 26:204–219
    • (2013) Dev Cell , vol.26 , pp. 204-219
    • Nolan, D.J.1    Ginsberg, M.2    Israely, E.3    Palikuqi, B.4    Poulos, M.G.5    James, D.6    Ding, B.S.7    Schachterle, W.8    Liu, Y.9    Rosenwaks, Z.10
  • 21
    • 84885756304 scopus 로고    scopus 로고
    • HIF-1alpha activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells
    • COI: 1:CAS:528:DC%2BC3sXhvVaqsrfF, PID: 24144209
    • Weidemann A, Breyer J, Rehm M, Eckardt KU, Daniel C, Cicha I, Giehl K, Goppelt-Struebe M (2013) HIF-1alpha activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells. Cell Commun Signal 11:80
    • (2013) Cell Commun Signal , vol.11 , pp. 80
    • Weidemann, A.1    Breyer, J.2    Rehm, M.3    Eckardt, K.U.4    Daniel, C.5    Cicha, I.6    Giehl, K.7    Goppelt-Struebe, M.8
  • 23
    • 65949084702 scopus 로고    scopus 로고
    • HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia
    • COI: 1:CAS:528:DC%2BD1MXmvFCiuro%3D, PID: 19342889
    • Hackenbeck T, Knaup KX, Schietke R, Schodel J, Willam C, Wu X, Warnecke C, Eckardt KU, Wiesener MS (2009) HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia. Cell Cycle 8:1386–1395
    • (2009) Cell Cycle , vol.8 , pp. 1386-1395
    • Hackenbeck, T.1    Knaup, K.X.2    Schietke, R.3    Schodel, J.4    Willam, C.5    Wu, X.6    Warnecke, C.7    Eckardt, K.U.8    Wiesener, M.S.9
  • 24
    • 0035865048 scopus 로고    scopus 로고
    • Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo
    • COI: 1:CAS:528:DC%2BD3MXnsV2qsw%3D%3D, PID: 11161575
    • Kisanuki YY, Hammer RE, Miyazaki J, Williams SC, Richardson JA, Yanagisawa M (2001) Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. Dev Biol 230:230–242
    • (2001) Dev Biol , vol.230 , pp. 230-242
    • Kisanuki, Y.Y.1    Hammer, R.E.2    Miyazaki, J.3    Williams, S.C.4    Richardson, J.A.5    Yanagisawa, M.6
  • 26
    • 61449154547 scopus 로고    scopus 로고
    • Immunodesign of experimental sepsis by cecal ligation and puncture
    • COI: 1:CAS:528:DC%2BD1cXhsFCku7rO, PID: 19131954
    • Rittirsch D, Huber-Lang MS, Flierl MA, Ward PA (2009) Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 4:31–36
    • (2009) Nat Protoc , vol.4 , pp. 31-36
    • Rittirsch, D.1    Huber-Lang, M.S.2    Flierl, M.A.3    Ward, P.A.4
  • 29
    • 33947275633 scopus 로고    scopus 로고
    • Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in experimental glomerulonephritis in mice
    • COI: 1:CAS:528:DC%2BD2sXjs1Grs7o%3D, PID: 17287428
    • Daniel C, Amann K, Hohenstein B, Bornstein P, Hugo C (2007) Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in experimental glomerulonephritis in mice. J Am Soc Nephrol 18:788–798
    • (2007) J Am Soc Nephrol , vol.18 , pp. 788-798
    • Daniel, C.1    Amann, K.2    Hohenstein, B.3    Bornstein, P.4    Hugo, C.5
  • 30
    • 77951162370 scopus 로고    scopus 로고
    • FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells
    • COI: 1:CAS:528:DC%2BC3cXhs1altbo%3D, PID: 20018872
    • Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M (2010) FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells. J Biol Chem 285:4328–4336
    • (2010) J Biol Chem , vol.285 , pp. 4328-4336
    • Samarin, J.1    Wessel, J.2    Cicha, I.3    Kroening, S.4    Warnecke, C.5    Goppelt-Struebe, M.6
  • 31
    • 7944224442 scopus 로고    scopus 로고
    • Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
    • COI: 1:CAS:528:DC%2BD2cXhtVGlurjN, PID: 15542432
    • Tang N, Wang L, Esko J, Giordano FJ, Huang Y, Gerber HP, Ferrara N, Johnson RS (2004) Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 6:485–495
    • (2004) Cancer Cell , vol.6 , pp. 485-495
    • Tang, N.1    Wang, L.2    Esko, J.3    Giordano, F.J.4    Huang, Y.5    Gerber, H.P.6    Ferrara, N.7    Johnson, R.S.8
  • 32
    • 2442544693 scopus 로고    scopus 로고
    • Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha
    • COI: 1:CAS:528:DC%2BD2cXivVKhtbY%3D, PID: 14744852
    • Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, Clerici C (2004) Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem 279:14871–14878
    • (2004) J Biol Chem , vol.279 , pp. 14871-14878
    • Uchida, T.1    Rossignol, F.2    Matthay, M.A.3    Mounier, R.4    Couette, S.5    Clottes, E.6    Clerici, C.7
  • 33
    • 0037214282 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia
    • COI: 1:CAS:528:DC%2BD3sXhtVOrug%3D%3D, PID: 12482987
    • Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS (2003) Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol 23:359–369
    • (2003) Mol Cell Biol , vol.23 , pp. 359-369
    • Goda, N.1    Ryan, H.E.2    Khadivi, B.3    McNulty, W.4    Rickert, R.C.5    Johnson, R.S.6
  • 34
    • 0033067572 scopus 로고    scopus 로고
    • Increases in oxygen tension stimulate expression of ICAM-1 and VCAM-1 on human endothelial cells
    • COI: 1:CAS:528:DyaK1MXksVWnu7w%3D, PID: 10362686
    • Willam C, Schindler R, Frei U, Eckardt KU (1999) Increases in oxygen tension stimulate expression of ICAM-1 and VCAM-1 on human endothelial cells. Am J Physiol 276:H2044–H2052
    • (1999) Am J Physiol , vol.276 , pp. H2044-H2052
    • Willam, C.1    Schindler, R.2    Frei, U.3    Eckardt, K.U.4
  • 35
    • 33646519915 scopus 로고    scopus 로고
    • Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects
    • COI: 1:CAS:528:DC%2BD28XjvF2ksrg%3D, PID: 16557230
    • Yasuda H, Yuen PS, Hu X, Zhou H, Star RA (2006) Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int 69:1535–1542
    • (2006) Kidney Int , vol.69 , pp. 1535-1542
    • Yasuda, H.1    Yuen, P.S.2    Hu, X.3    Zhou, H.4    Star, R.A.5
  • 36
    • 78049378469 scopus 로고    scopus 로고
    • The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease
    • COI: 1:CAS:528:DC%2BC3cXhtlCjsL7F, PID: 20877304
    • Mimura I, Nangaku M (2010) The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease. Nat Rev Nephrol 6:667–678
    • (2010) Nat Rev Nephrol , vol.6 , pp. 667-678
    • Mimura, I.1    Nangaku, M.2
  • 37
    • 84884238023 scopus 로고    scopus 로고
    • Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus
    • COI: 1:CAS:528:DC%2BC3sXhtl2jsLbO
    • Jiang X, Hsu JL, Tian W, Yuan K, Olcholski M, Perez Vde J, Semenza GL, Nicolls MR (2013) Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. J Mol Med (Berl) 91:1081–1093
    • (2013) J Mol Med (Berl) , vol.91 , pp. 1081-1093
    • Jiang, X.1    Hsu, J.L.2    Tian, W.3    Yuan, K.4    Olcholski, M.5    Perez Vde, J.6    Semenza, G.L.7    Nicolls, M.R.8
  • 38
    • 84555188569 scopus 로고    scopus 로고
    • Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells
    • COI: 1:CAS:528:DC%2BC3MXhs1ygurzP, PID: 22028336
    • Sarkar K, Rey S, Zhang X, Sebastian R, Marti GP, Fox-Talbot K, Cardona AV, Du J, Tan YS, Liu L et al (2012) Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells. Cardiovasc Res 93:162–169
    • (2012) Cardiovasc Res , vol.93 , pp. 162-169
    • Sarkar, K.1    Rey, S.2    Zhang, X.3    Sebastian, R.4    Marti, G.P.5    Fox-Talbot, K.6    Cardona, A.V.7    Du, J.8    Tan, Y.S.9    Liu, L.10
  • 39
    • 79957907464 scopus 로고    scopus 로고
    • Adenovirus-mediated HIF-1alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
    • COI: 1:CAS:528:DC%2BC3MXnsVaitr8%3D, PID: 21606594
    • Jiang X, Khan MA, Tian W, Beilke J, Natarajan R, Kosek J, Yoder MC, Semenza GL, Nicolls MR (2011) Adenovirus-mediated HIF-1alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. J Clin Invest 121:2336–2349
    • (2011) J Clin Invest , vol.121 , pp. 2336-2349
    • Jiang, X.1    Khan, M.A.2    Tian, W.3    Beilke, J.4    Natarajan, R.5    Kosek, J.6    Yoder, M.C.7    Semenza, G.L.8    Nicolls, M.R.9
  • 42
    • 0035145117 scopus 로고    scopus 로고
    • Angiopoietin growth factors and Tie receptor tyrosine kinases in renal vascular development
    • COI: 1:STN:280:DC%2BD3M7lvV2jtw%3D%3D, PID: 11261688
    • Woolf AS, Yuan HT (2001) Angiopoietin growth factors and Tie receptor tyrosine kinases in renal vascular development. Pediatr Nephrol 16:177–184
    • (2001) Pediatr Nephrol , vol.16 , pp. 177-184
    • Woolf, A.S.1    Yuan, H.T.2
  • 43
    • 0036086589 scopus 로고    scopus 로고
    • The use of microcomputed tomography to study microvasculature in small rodents
    • COI: 1:CAS:528:DC%2BD38XjslWmtbo%3D, PID: 11959666
    • Bentley MD, Ortiz MC, Ritman EL, Romero JC (2002) The use of microcomputed tomography to study microvasculature in small rodents. Am J Physiol Regul Integr Comp Physiol 282:R1267–R1279
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.282 , pp. R1267-R1279
    • Bentley, M.D.1    Ortiz, M.C.2    Ritman, E.L.3    Romero, J.C.4


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