Comparison of Therapeutic Effect of Recombinant Tissue Plasminogen Activator by Treatment Time after Onset of Acute Ischemic Stroke

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Hai Rong ^a   Chen, Miao ^a   Wang, Fei Long ^a   Dai, Li Hua ^a   Fei, Ai Hua ^a   Liu, Jia Fu ^a   Li, Hao Jun ^a   Shen, Sa ^a   Liu, Ming ^a   Pan, Shu Ming ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN; TISSUE PLASMINOGEN ACTIVATOR;

ADOLESCENT; ADULT; AGED; BRAIN ISCHEMIA; CLINICAL TRIAL; COMPARATIVE STUDY; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; MALE; MIDDLE AGED; PROCEDURES; STROKE; TIME FACTOR; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; FEMALE; HUMANS; MALE; MIDDLE AGED; RECOMBINANT PROTEINS; STROKE; THROMBOLYTIC THERAPY; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84937859351     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep11743     Document Type: Article

References (17)

1. Gao, X. et al. Admission clinical characteristics and early clinical outcomes among acute ischemic stroke patients. J Biomed Res 26, 152-158 (2012).
2. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 333, 1581-1587 (1995)
3. Barber, P. A., Zhang, J., Demchuk, A. M., Hill, M. D., Buchan, A. M. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology. 56, 1015-1020 (2001).
4. Hacke, W. et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA. 274, 1017-1025 (1995).
5. Hacke, W. et al. Randomised doubleblind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators. Lancet 352, 1245-1251 (1998).
6. Clark, W. M. et al. Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke. JAMA. 282, 2019-2026 (1999).
7. Hacke, W. et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 359, 1317-1329 (2008).
8. Wahlgren, N. et al. Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 372, 1303-1309 (2008).
9. Shobha, N., Buchan, A. M., Hill, M. D. Canadian Alteplase for Stroke Effectiveness Study (CASES). Thrombolysis at 3-4.5 hours after acute ischemic stroke onset-evidence from the Canadian Alteplase for Stroke Effectiveness Study (CASES) registry. Cerebrovasc Dis. 31, 223-228 (2011).
10. The IST-3 Collaborative Group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet. 23, 23 (2012).
11. Writing group of the National Guideline for diagnosis and treatment of acute ischemic stroke, Cerebrovascular Disease team, Neurology Sub-branch, Chinese Medical Association. National Guideline for diagnosis and treatment of acute ischemic stroke. Chin J Neurol. 43, 146-153 (2010).
12. Haanddie;hnel, S. et al. Local intra-arterial fibrinolysis of thromboemboli occurring during euroendovascular procedures with recombinant tissue plasminogen activator. Stroke. 34, 1723-1728 (2003).
13. Thurman, R. J., Jauch, E. C., Panagos, P. D., Reynolds, M. R., Mocco, J. Four evolving strategies in the emergent treatment of acute ischemic stroke. Emerg Med Pract 14, 1-26 (2012).
14. Acute ischemic stroke treatment guideline writing group, cerebrovascular science section, neurology branch of Chinese Medical Association. Chinese guidelines for treatment of acute ischemic stroke. Chin J Neurol 43, 146-153 (2010).
15. Whiteh, Segal. Treatment of acute ischemic troke Current medical literature. Neurology. 24, 61-81 (2008).
16. Liu, M. Neurologic Medicine. [Liu, M. (ed).] [53] (Peopleandquot;s Health Publishing House, Beijing, 2008).
17. Del Zoppo, G. J., Saver, J. L., Jauch, E. C., Adams, H. P. Jr and American Heart Association Stroke Council. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator. A science advisory from the American Heart Association/American Stroke Association. Stroke. 40, 2945-2948 (2009).