Cost and mortality associated with postoperative acute kidney injury

Annals of Surgery

Volumn 261, Issue 6, 2015, Pages 1207-1214

  Hobson, Charles ^a,b   Ozrazgat Baslanti, Tezcan ^c   Kuxhausen, Adrienne ^c   Thottakkara, Paul ^c   Efron, Philip A ^c   Moore, Frederick A ^c   Moldawer, Lyle L ^c   Segal, Mark S ^a,c   Bihorac, Azra ^c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Acute kidney injury; Cost; Mortality; Outcomes assessment; Postoperative complications; Risk adjusted regression models

Indexed keywords

CREATININE;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; ARTIFICIAL VENTILATION; CARDIOVASCULAR DISEASE; COMORBIDITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; GASTROINTESTINAL DISEASE; HOSPITAL COST; HUMAN; ICD-9-CM; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NEUROLOGICAL COMPLICATION; PATIENT SAFETY; POSTOPERATIVE ACUTE KIDNEY INJURY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE DELIRIUM; PREVALENCE; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; SURGICAL INFECTION; SURGICAL MORTALITY; SURGICAL PATIENT; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM; WOUND COMPLICATION; ACUTE KIDNEY INJURY; AGED; COHORT ANALYSIS; ECONOMICS; HOSPITAL MORTALITY; MORTALITY; POSTOPERATIVE COMPLICATIONS; REGRESSION ANALYSIS; RISK ASSESSMENT; STATISTICS AND NUMERICAL DATA; SURVIVAL ANALYSIS;

ACUTE KIDNEY INJURY; ADULT; AGED; COHORT STUDIES; COMORBIDITY; FEMALE; HOSPITAL COSTS; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PREVALENCE; REGRESSION ANALYSIS; RISK ADJUSTMENT; SURVIVAL ANALYSIS;

EID: 84937845363     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000000732     Document Type: Article

References (40)

1. Lee PH, Gawande AA. The number of surgical procedures in an American lifetime in 3 states. J Am Coll Surg. 2008;207:S75-S75.
2. Weiser TG, Regenbogen SE, Thompson KD, et al. An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet. 2008;372:139-144.
3. Dimick JB, Weeks WB, Karia RJ, et al. Who pays for poor surgical quality? Building a business case for quality improvement. J Am Coll Surg. 2006;202:933-997.
4. Birkmeyer JD, Gust C, Dimick JB, et al. Hospital quality and the cost of inpatient surgery in the United States. Ann Surg. 2012;255:1-5.
5. Hall BL, Hamilton BH, Richards K, et al. Does surgical quality improve in the American College of Surgeons National Surgical Quality Improvement Program: an evaluation of all participating hospitals. Ann Surg. 2009;250:363-376.
6. Vaughan-Sarrazin M, Bayman L, Rosenthal G, et al. The business case for the reduction of surgical complications in VA hospitals. Surgery. 2011;149:474-483.
7. Bihorac A, Delano MJ, Schold JD, et al. Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients. Ann Surg. 2010;252:158-165.
8. Hobson CE, Yavas S, Segal MS, et al. Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery. Circulation. 2009;119:2444-2453.
9. Bihorac A, Yavas S, Subbiah S, et al. Long-termrisk of mortality and acute kidney injury during hospitalization after major surgery. Ann Surg. 2009;249:851-858.
10. Cuthbertson BH, Roughton S, Jenkinson D, et al. Quality of life in the five years after intensive care: a cohort study. Crit Care. 2010;14:R6.
11. Ishani A, Nelson D, Clothier B, et al. The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death. Arch Intern Med. 2011;171:226-233.
12. Dasta JF, Kane-Gill SL, Durtschi AJ, et al. Costs and outcomes of acute kidney injury (AKI) following cardiac surgery. Nephrol Dial Transplant. 2008;23:1970-1974.
13. Dimick JB, Chen SL, Taheri PA, et al. Hospital costs associated with surgical complications: a report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg. 2004;199:531-537.
14. Dimick JB, Pronovost PJ, Cowan JA, et al. Complications and costs after highrisk surgery: where should we focus quality improvement initiatives? J Am Coll Surg. 2003;196:671-678.
15. Vaughan-Sarrazin MS, Bayman L, Cullen JJ. Costs of postoperative sepsis: the business case for quality improvement to reduce postoperative sepsis in veterans affairs hospitals. Arch Surg. 2011;146:944-951.
16. Chertow GM, Burdick E, Honour M, et al. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16:3365-3370.
17. White LE, Chaudhary R, Moore LJ, et al. Surgical sepsis and organ crosstalk: the role of the kidney. J Surg Res. 2011;167:306-315.
18. Bihorac A, Brennan M, Ozrazgat Baslanti T, et al. National surgical quality improvement program underestimates the risk associated with mild and moderate postoperative acute kidney injury. Crit Care Med. 2013;41:2570-2583.
19. Wald R, Waikar SS, Liangos O, et al. Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm. J Vasc Surg. 2006;43:460-466; discussion 466.
20. Bellomo R, Ronco C, Kellum JA, et al. Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8:R204-R212.
21. Siew ED, Ikizler T, Matheny ME, et al. Estimating baseline kidney function in hospitalized patients with impaired kidney function. J Am Soc Nephrol. 2012;7:712-720.
22. LaPar DJ, Bhamidipati CM, Mery CM, et al. Primary payer status affects mortality for major surgical operations. Ann Surg. 2010;252:544-550; discussion 550-551.
23. Guller U, Hervey S, Purves H, et al. Laparoscopic versus open appendectomy: outcomes comparison based on a large administrative database. Ann Surg. 2004;239:43-52.
24. Agency for Healthcare Research and Quality. Patient safety indicators: technical specifications. Ver. 4.2 2010. Available at: http://www.qualityindicators. ahrq.gov. Accessed April 9, 2012.
25. Dombrovskiy VY, Martin AA, Sunderram J, et al. Facing the challenge: decreasing case fatality rates in severe sepsis despite increasing hospitalizations. Crit Care Med. 2005;33:2555-2562.
26. Elixhauser A, Steiner C, Harris DR, et al. Comorbidity measures for use with administrative data. Med Care. 1998;36:8-27.
27. Charlson ME, Pompei P, Ales KL, et al. Anewmethod of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383.
28. HCUP Cost-to-Charge Ratio Files (CCR). Healthcare Cost and Utilization Project (HCUP). 2000-2010. Rockville, MD: Agency for Healthcare Research and Quality. Available at: www.hcup-us.ahrq.gov/db/state/costtocharge.jsp. Accessed May 21, 2014.
29. von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med. 2007;147:573-577.
30. Pasta DJ. Estimating standard errors for CLASS variables in generalized linear models using PROC IML. In: Proceedings of the 28th Annual SAS Users Group International Conference. Cary, NC: SAS Institute Inc; 2003. Paper 264-28.
31. Duan N. Smearing estimate: a nonparametric retransformation method. J Am Stat Assoc. 1983;78:605-610.
32. White LE, Hassoun HT, Bihorac A, et al. Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis. J Trauma Acute Care Surg. 2013;75:432-438.
33. Hoste EA, De Corte W. Clinical consequences of acute kidney injury. Contrib Nephrol. 2011;174:56-64.
34. Grams ME, Estrella MM, Coresh J, et al. Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol. 2011;6:966-973.
35. Bouchard J, Soroko SB, Chertow GM, et al. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int. 2009;76:422-427.
36. Grigoryev DN, Liu M, Hassoun HT, et al. The local and systemic inflammatory transcriptome after acute kidney injury. J Am Soc Nephrol. 2008;19: 547-558.
37. Bihorac A, Baslanti TO, Cuenca AG, et al. Acute kidney injury is associated with early cytokine changes after trauma. J Trauma Acute Care Surg. 2013;74:1005-1013.
38. Bihorac A, Efron PA, Ang D, et al. Acute kidney injury is associated with nosocomial infections and surgical site infections after trauma. Surg Infect. 2011;12:S017.
39. Khuri SFMD, Henderson WGP, DePalma RGMD, et al. Determinants of longterm survival after major surgery and the adverse effect of postoperative complications. Ann Surg. 2005;242:326-343.
40. Kidney Disease: Improving Global Outcomes Acute Kidney Injury Work Group. Clinical practice guideline for acute kidney injury: AKI definition. Kidney Int Suppl. 2012; 2:19-36.