Crystal structure of human persulfide dioxygenase: Structural basis of ethylmalonic encephalopathy

Human Molecular Genetics

Volumn 24, Issue 9, 2015, Pages 2458-2469

  Pettinati, Ilaria ^a   Brem, Jürgen ^a   McDonough, Michael A ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; DIOXYGENASE; GLUTATHIONE DERIVATIVE; GLUTATHIONE PERSULFIDE; HISTIDINE; HUMAN ETHYLMALONIC ENCEPHALOPATHY PROTEIN 1; IRON; IRON BINDING PROTEIN; METALLO BETA LACTAMASE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; ZINC; ZINC BINDING PROTEIN; ETHE1 PROTEIN, HUMAN; METAL; MITOCHONDRIAL PROTEIN; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; PROTEIN BINDING;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE MUTATION; HUMAN; IRON BINDING CAPACITY; METAL BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; GENETICS; METABOLIC ENCEPHALOPATHY; METABOLISM; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR GENETICS; MUTATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; PURPURA; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; BRAIN DISEASES, METABOLIC, INBORN; CATALYTIC DOMAIN; ENZYME ACTIVATION; HUMANS; METALS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PURPURA; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84937831776     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv007     Document Type: Article

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