-
1
-
-
84937944692
-
PIP4K and the role of nuclear phosphoinositides in tumour suppression
-
Fiume R., Stijf-Bultsma Y., Shah Z.H., Keune W.J., Jones D.R., Jude J., Divecha N. PIP4K and the role of nuclear phosphoinositides in tumour suppression. Biochim. Biophys. Acta 2015, 1851:898-910.
-
(2015)
Biochim. Biophys. Acta
, vol.1851
, pp. 898-910
-
-
Fiume, R.1
Stijf-Bultsma, Y.2
Shah, Z.H.3
Keune, W.J.4
Jones, D.R.5
Jude, J.6
Divecha, N.7
-
2
-
-
59849125052
-
Mutations in phosphoinositide metabolizing enzymes and human disease
-
McCrea H.J., De Camilli P. Mutations in phosphoinositide metabolizing enzymes and human disease. Physiology (Bethesda) 2009, 24:8-16.
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 8-16
-
-
McCrea, H.J.1
De Camilli, P.2
-
3
-
-
84856244294
-
The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia
-
Polak R., Buitenhuis M. The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia. Blood 2012, 119:911-923.
-
(2012)
Blood
, vol.119
, pp. 911-923
-
-
Polak, R.1
Buitenhuis, M.2
-
4
-
-
84893249799
-
PI3K and cancer: lessons, challenges and opportunities
-
Fruman D.A., Rommel C. PI3K and cancer: lessons, challenges and opportunities. Nat. Rev. Drug Discov. 2014, 13:140-156.
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 140-156
-
-
Fruman, D.A.1
Rommel, C.2
-
5
-
-
0034101950
-
Mutation analysis of PTEN/MMAC1 in acute myeloid leukemia
-
Liu T.C., Lin P.M., Chang J.G., Lee J.P., Chen T.P., Lin S.F. Mutation analysis of PTEN/MMAC1 in acute myeloid leukemia. Am. J. Hematol. 2000, 63:170-175.
-
(2000)
Am. J. Hematol.
, vol.63
, pp. 170-175
-
-
Liu, T.C.1
Lin, P.M.2
Chang, J.G.3
Lee, J.P.4
Chen, T.P.5
Lin, S.F.6
-
6
-
-
0032212223
-
PTEN gene alterations in lymphoid neoplasms
-
Sakai A., Thieblemont C., Wellmann A., Jaffe E.S., Raffeld M. PTEN gene alterations in lymphoid neoplasms. Blood 1998, 92:3410-3415.
-
(1998)
Blood
, vol.92
, pp. 3410-3415
-
-
Sakai, A.1
Thieblemont, C.2
Wellmann, A.3
Jaffe, E.S.4
Raffeld, M.5
-
7
-
-
0031855499
-
Mutational analysis of the PTEN/MMAC1 gene in non-Hodgkin's lymphoma
-
Nakahara Y., Nagai H., Kinoshita T., Uchida T., Hatano S., Murate T., Saito H. Mutational analysis of the PTEN/MMAC1 gene in non-Hodgkin's lymphoma. Leukemia 1998, 12:1277-1280.
-
(1998)
Leukemia
, vol.12
, pp. 1277-1280
-
-
Nakahara, Y.1
Nagai, H.2
Kinoshita, T.3
Uchida, T.4
Hatano, S.5
Murate, T.6
Saito, H.7
-
8
-
-
84896691622
-
A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival
-
Jude J.G., Spencer G.J., Huang X., Somerville T.D., Jones D.R., Divecha N., Somervaille T.C. A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival. Oncogene 2014, 34:1253-1262.
-
(2014)
Oncogene
, vol.34
, pp. 1253-1262
-
-
Jude, J.G.1
Spencer, G.J.2
Huang, X.3
Somerville, T.D.4
Jones, D.R.5
Divecha, N.6
Somervaille, T.C.7
-
9
-
-
0024518870
-
Characterization and purification of membrane-associated phosphatidylinositol-4-phosphate kinase from human red blood cells
-
Ling L.E., Schulz J.T., Cantley L.C. Characterization and purification of membrane-associated phosphatidylinositol-4-phosphate kinase from human red blood cells. J. Biol. Chem. 1989, 264:5080-5088.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 5080-5088
-
-
Ling, L.E.1
Schulz, J.T.2
Cantley, L.C.3
-
10
-
-
0029089452
-
The cloning and sequence of the C isoform of PtdIns4P 5-kinase
-
Divecha N., Truong O., Hsuan J.J., Hinchliffe K.A., Irvine R.F. The cloning and sequence of the C isoform of PtdIns4P 5-kinase. Biochem. J. 1995, 309(Pt 3):715-719.
-
(1995)
Biochem. J.
, vol.309
, pp. 715-719
-
-
Divecha, N.1
Truong, O.2
Hsuan, J.J.3
Hinchliffe, K.A.4
Irvine, R.F.5
-
11
-
-
84887933383
-
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors
-
Emerling B.M., Hurov J.B., Poulogiannis G., Tsukazawa K.S., Choo-Wing R., Wulf G.M., Bell E.L., Shim H.S., Lamia K.A., Rameh L.E., Bellinger G., Sasaki A.T., Asara J.M., Yuan X., Bullock A., Denicola G.M., Song J., Brown V., Signoretti S., Cantley L.C. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors. Cell 2013, 155:844-857.
-
(2013)
Cell
, vol.155
, pp. 844-857
-
-
Emerling, B.M.1
Hurov, J.B.2
Poulogiannis, G.3
Tsukazawa, K.S.4
Choo-Wing, R.5
Wulf, G.M.6
Bell, E.L.7
Shim, H.S.8
Lamia, K.A.9
Rameh, L.E.10
Bellinger, G.11
Sasaki, A.T.12
Asara, J.M.13
Yuan, X.14
Bullock, A.15
Denicola, G.M.16
Song, J.17
Brown, V.18
Signoretti, S.19
Cantley, L.C.20
more..
-
12
-
-
84866621729
-
Revised international prognostic scoring system for myelodysplastic syndromes
-
Greenberg P.L., Tuechler H., Schanz J., Sanz G., Garcia-Manero G., Sole F., Bennett J.M., Bowen D., Fenaux P., Dreyfus F., Kantarjian H., Kuendgen A., Levis A., Malcovati L., Cazzola M., Cermak J., Fonatsch C., Le Beau M.M., Slovak M.L., Krieger O., Luebbert M., Maciejewski J., Magalhaes S.M., Miyazaki Y., Pfeilstocker M., Sekeres M., Sperr W.R., Stauder R., Tauro S., Valent P., Vallespi T., van de Loosdrecht A.A., Germing U., Haase D. Revised international prognostic scoring system for myelodysplastic syndromes. Blood 2012, 120:2454-2465.
-
(2012)
Blood
, vol.120
, pp. 2454-2465
-
-
Greenberg, P.L.1
Tuechler, H.2
Schanz, J.3
Sanz, G.4
Garcia-Manero, G.5
Sole, F.6
Bennett, J.M.7
Bowen, D.8
Fenaux, P.9
Dreyfus, F.10
Kantarjian, H.11
Kuendgen, A.12
Levis, A.13
Malcovati, L.14
Cazzola, M.15
Cermak, J.16
Fonatsch, C.17
Le Beau, M.M.18
Slovak, M.L.19
Krieger, O.20
Luebbert, M.21
Maciejewski, J.22
Magalhaes, S.M.23
Miyazaki, Y.24
Pfeilstocker, M.25
Sekeres, M.26
Sperr, W.R.27
Stauder, R.28
Tauro, S.29
Valent, P.30
Vallespi, T.31
van de Loosdrecht, A.A.32
Germing, U.33
Haase, D.34
more..
-
13
-
-
84858830672
-
New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge
-
Schanz J., Tuchler H., Sole F., Mallo M., Luno E., Cervera J., Granada I., Hildebrandt B., Slovak M.L., Ohyashiki K., Steidl C., Fonatsch C., Pfeilstocker M., Nosslinger T., Valent P., Giagounidis A., Aul C., Lubbert M., Stauder R., Krieger O., Garcia-Manero G., Faderl S., Pierce S., Le Beau M.M., Bennett J.M., Greenberg P., Germing U., Haase D. New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge. J. Clin. Oncol. 2012, 30:820-829.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 820-829
-
-
Schanz, J.1
Tuchler, H.2
Sole, F.3
Mallo, M.4
Luno, E.5
Cervera, J.6
Granada, I.7
Hildebrandt, B.8
Slovak, M.L.9
Ohyashiki, K.10
Steidl, C.11
Fonatsch, C.12
Pfeilstocker, M.13
Nosslinger, T.14
Valent, P.15
Giagounidis, A.16
Aul, C.17
Lubbert, M.18
Stauder, R.19
Krieger, O.20
Garcia-Manero, G.21
Faderl, S.22
Pierce, S.23
Le Beau, M.M.24
Bennett, J.M.25
Greenberg, P.26
Germing, U.27
Haase, D.28
more..
-
14
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties
-
Grimwade D., Walker H., Oliver F., Wheatley K., Harrison C., Harrison G., Rees J., Hann I., Stevens R., Burnett A., Goldstone A. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 1998, 92:2322-2333.
-
(1998)
Blood
, vol.92
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
Wheatley, K.4
Harrison, C.5
Harrison, G.6
Rees, J.7
Hann, I.8
Stevens, R.9
Burnett, A.10
Goldstone, A.11
-
15
-
-
53249123632
-
-
IARC, Lyon
-
Swerdlow S.H., Campo E., Harris N.L., Jaffe E.S., Pileri S.A., Stein H., Thiele J., Vardiman J.W. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008, IARC, Lyon. Fourth ed.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
-
-
Swerdlow, S.H.1
Campo, E.2
Harris, N.L.3
Jaffe, E.S.4
Pileri, S.A.5
Stein, H.6
Thiele, J.7
Vardiman, J.W.8
-
16
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
17
-
-
77956677775
-
PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha
-
Bultsma Y., Keune W.J., Divecha N. PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha. Biochem. J. 2010, 430:223-235.
-
(2010)
Biochem. J.
, vol.430
, pp. 223-235
-
-
Bultsma, Y.1
Keune, W.J.2
Divecha, N.3
-
18
-
-
84903454922
-
PIPKIIalpha is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells
-
Peretti de Albuquerque Wobeto V., Machado-Neto J.A., Zaccariotto T.R., Ribeiro D.M., da Silva Santos Duarte A., Saad S.T., Costa F.F., de Fatima Sonati M. PIPKIIalpha is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells. Mol. Cell. Biochem. 2014, 393:145-153.
-
(2014)
Mol. Cell. Biochem.
, vol.393
, pp. 145-153
-
-
Peretti de Albuquerque Wobeto, V.1
Machado-Neto, J.A.2
Zaccariotto, T.R.3
Ribeiro, D.M.4
da Silva Santos Duarte, A.5
Saad, S.T.6
Costa, F.F.7
de Fatima Sonati, M.8
-
19
-
-
33748193467
-
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta
-
Jones D.R., Bultsma Y., Keune W.J., Halstead J.R., Elouarrat D., Mohammed S., Heck A.J., D'Santos C.S., Divecha N. Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta. Mol. Cell 2006, 23:685-695.
-
(2006)
Mol. Cell
, vol.23
, pp. 685-695
-
-
Jones, D.R.1
Bultsma, Y.2
Keune, W.J.3
Halstead, J.R.4
Elouarrat, D.5
Mohammed, S.6
Heck, A.J.7
D'Santos, C.S.8
Divecha, N.9
-
20
-
-
31444440033
-
Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients
-
Nyakern M., Tazzari P.L., Finelli C., Bosi C., Follo M.Y., Grafone T., Piccaluga P.P., Martinelli G., Cocco L., Martelli A.M. Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients. Leukemia 2006, 20:230-238.
-
(2006)
Leukemia
, vol.20
, pp. 230-238
-
-
Nyakern, M.1
Tazzari, P.L.2
Finelli, C.3
Bosi, C.4
Follo, M.Y.5
Grafone, T.6
Piccaluga, P.P.7
Martinelli, G.8
Cocco, L.9
Martelli, A.M.10
-
21
-
-
84904383690
-
Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (review)
-
Evangelisti C., Chiarini F., Lonetti A., Buontempo F., Bressanin D., Cappellini A., Orsini E., McCubrey J.A., Martelli A.M. Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (review). Int. J. Oncol. 2014, 45:909-918.
-
(2014)
Int. J. Oncol.
, vol.45
, pp. 909-918
-
-
Evangelisti, C.1
Chiarini, F.2
Lonetti, A.3
Buontempo, F.4
Bressanin, D.5
Cappellini, A.6
Orsini, E.7
McCubrey, J.A.8
Martelli, A.M.9
-
22
-
-
84875499996
-
Expression profiles of phosphatidylinositol phosphate kinase genes during normal human in vitro erythropoiesis
-
Zaccariotto T.R., Lanaro C., Albuquerque D.M., Santos M.N., Bezerra M.A., Cunha F.G., Lorand-Metze I., Araujo A.S., Costa F.F., Sonati M.F. Expression profiles of phosphatidylinositol phosphate kinase genes during normal human in vitro erythropoiesis. Genet. Mol. Res. 2012, 11:3861-3868.
-
(2012)
Genet. Mol. Res.
, vol.11
, pp. 3861-3868
-
-
Zaccariotto, T.R.1
Lanaro, C.2
Albuquerque, D.M.3
Santos, M.N.4
Bezerra, M.A.5
Cunha, F.G.6
Lorand-Metze, I.7
Araujo, A.S.8
Costa, F.F.9
Sonati, M.F.10
-
23
-
-
84890283717
-
Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: a role for PIP4K2B in the regulation of E-cadherin expression
-
Keune W.J., Sims A.H., Jones D.R., Bultsma Y., Lynch J.T., Jirstrom K., Landberg G., Divecha N. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: a role for PIP4K2B in the regulation of E-cadherin expression. Cancer Res. 2013, 73:6913-6925.
-
(2013)
Cancer Res.
, vol.73
, pp. 6913-6925
-
-
Keune, W.J.1
Sims, A.H.2
Jones, D.R.3
Bultsma, Y.4
Lynch, J.T.5
Jirstrom, K.6
Landberg, G.7
Divecha, N.8
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