Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

Immunity

Volumn 43, Issue 1, 2015, Pages 80-91

  Yuk, Jae Min ^a   Kim, Tae Sung ^a   Kim, Soo Yeon ^a   Lee, Hye Mi ^a   Han, Jeongsu ^a   Dufour, Catherine Rosa ^b   Kim, Jin Kyung ^a   Jin, Hyo Sun ^a   Yang, Chul Su ^c   Park, Ki Sun ^d   Lee, Chul Ho ^e   Kim, Jin Man ^a   Kweon, Gi Ryang ^a   Choi, Hueng Sik ^f   Vanacker, Jean Marc ^g   Moore, David D ^h   Giguère, Vincent ^b   Jo, Eun Kyeong ^a  

^a Chungnam National University   (South Korea)

^b MCGILL UNIVERSITY   (Canada)

^c Hanyang University   (South Korea)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^f Chonnam National University   (South Korea)

^g UNIVERSITÉ LYON 1   (France)

^h BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; DECTIN 1; ESTROGEN RELATED RECEPTOR ALPHA; GALACTOSE; GLUCOSE TRANSPORTER 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOCHONDRIAL DNA; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PYRUVIC ACID; SHORT HAIRPIN RNA; SIRTUIN 1; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; ZYMOSAN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CYSTEINE PROTEINASE; ERRALPHA ESTROGEN-RELATED RECEPTOR; ESTROGEN RECEPTOR; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; NICOTINAMIDE ADENINE DINUCLEOTIDE; RELA PROTEIN, MOUSE; SIGNAL PEPTIDE; SIRT1 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TNFAIP3 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CHROMATIN IMMUNOPRECIPITATION; CITRIC ACID CYCLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA CONTENT; FATTY ACID OXIDATION; GLYCOLYSIS; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE; MACROPHAGE; MICROARRAY ANALYSIS; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ACETYLATION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; REAL TIME POLYMERASE CHAIN REACTION; SEPTIC SHOCK; SURVIVAL RATE; TRANSCRIPTION INITIATION; UBIQUITINATION; UPREGULATION; ACETYLATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; OXIDATIVE PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACETYLATION; ANIMALS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; GLYCOLYSIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NAD; OXIDATIVE PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RECEPTORS, ESTROGEN; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; SIRTUIN 1; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; UBIQUITINATION;

EID: 84937714668     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.07.003     Document Type: Article

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