-
1
-
-
0036083695
-
The proximal colonic motor response to rectal mechanical and chemical stimulation
-
Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. The proximal colonic motor response to rectal mechanical and chemical stimulation. Am J Physiol Gastrointest Liver Physiol. 2002;282:G443-449.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
, pp. G443-449
-
-
Bampton, P.A.1
Dinning, P.G.2
Kennedy, M.L.3
Lubowski, D.Z.4
Cook, I.J.5
-
2
-
-
0015105518
-
Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man
-
Mekjian HS, Phillips SF, Hofmann AF. Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man. J Clin Invest. 1971;50:1569-77.
-
(1971)
J Clin Invest
, vol.50
, pp. 1569-1577
-
-
Mekjian, H.S.1
Phillips, S.F.2
Hofmann, A.F.3
-
3
-
-
80053912847
-
A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation
-
Chey WD, Camilleri M, Chang L, Rikner L, Graffner H. A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation. Am J Gastroenterol. 2011;106:1803-12.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 1803-1812
-
-
Chey, W.D.1
Camilleri, M.2
Chang, L.3
Rikner, L.4
Graffner, H.5
-
4
-
-
79958173090
-
Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation - a double-blind study
-
Simren M, Bajor A, Gillberg PG, Rudling M, Abrahamsson H. Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation - a double-blind study. Aliment Pharmacol Ther. 2011;34:41-50.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 41-50
-
-
Simren, M.1
Bajor, A.2
Gillberg, P.G.3
Rudling, M.4
Abrahamsson, H.5
-
5
-
-
82955195427
-
Effects of A3309, an ileal bile acid transporter inhibitor, on colonic transit and symptoms in females with functional constipation
-
Wong BS, Camilleri M, McKinzie S, Burton D, Graffner H, Zinsmeister AR. Effects of A3309, an ileal bile acid transporter inhibitor, on colonic transit and symptoms in females with functional constipation. Am J Gastroenterol. 2011;106:2154-64.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 2154-2164
-
-
Wong, B.S.1
Camilleri, M.2
McKinzie, S.3
Burton, D.4
Graffner, H.5
Zinsmeister, A.R.6
-
6
-
-
79959525960
-
The bile acid membrane receptor TGR5: a valuable metabolic target
-
Pols TW, Noriega LG, Nomura M, Auwerx J, Schoonjans K. The bile acid membrane receptor TGR5: a valuable metabolic target. Dig Dis. 2011;29:37-44.
-
(2011)
Dig Dis
, vol.29
, pp. 37-44
-
-
Pols, T.W.1
Noriega, L.G.2
Nomura, M.3
Auwerx, J.4
Schoonjans, K.5
-
7
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009;10:167-77.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
Strehle, A.4
Oury, J.5
Rizzo, G.6
Macchiarulo, A.7
Yamamoto, H.8
Mataki, C.9
Pruzanski, M.10
-
8
-
-
0142074212
-
Monitoring hepatic cholesterol 7{alpha}-hydroxylase activity by assay of the stable bile acid intermediate 7{alpha}-hydroxy-4-cholesten-3-one in peripheral blood
-
Galman C, Arvidsson I, Angelin B, Rudling M. Monitoring hepatic cholesterol 7{alpha}-hydroxylase activity by assay of the stable bile acid intermediate 7{alpha}-hydroxy-4-cholesten-3-one in peripheral blood. J Lipid Res. 2003;44:859-66.
-
(2003)
J Lipid Res
, vol.44
, pp. 859-866
-
-
Galman, C.1
Arvidsson, I.2
Angelin, B.3
Rudling, M.4
-
9
-
-
13844299425
-
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
-
Katsuma S, Hirasawa A, Tsujimoto G. Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1. Biochem Biophys Res Commun. 2005;329:386-90.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 386-390
-
-
Katsuma, S.1
Hirasawa, A.2
Tsujimoto, G.3
-
10
-
-
84874031840
-
Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
-
Potthoff MJ, Potts A, He T, Duarte JA, Taussig R, Mangelsdorf DJ, et al. Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice. Am J Physiol Gastrointest Liver Physiol. 2013;304:G371-380.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. G371-380
-
-
Potthoff, M.J.1
Potts, A.2
He, T.3
Duarte, J.A.4
Taussig, R.5
Mangelsdorf, D.J.6
Kliewer, S.A.7
Burgess, S.C.8
-
12
-
-
0016756636
-
Inhibition of bile salt absorption by blood-sugar lowering biguanides
-
Caspary WF, Creutzfeldt W. Inhibition of bile salt absorption by blood-sugar lowering biguanides. Diabetologia. 1975;11:113-7.
-
(1975)
Diabetologia
, vol.11
, pp. 113-117
-
-
Caspary, W.F.1
Creutzfeldt, W.2
-
13
-
-
0031847175
-
Effect of metformin on bile salt circulation and intestinal motility in type 2 diabetes mellitus
-
Scarpello JH, Hodgson E, Howlett HC. Effect of metformin on bile salt circulation and intestinal motility in type 2 diabetes mellitus. Diabet Med. 1998;15:651-6.
-
(1998)
Diabet Med
, vol.15
, pp. 651-656
-
-
Scarpello, J.H.1
Hodgson, E.2
Howlett, H.C.3
-
15
-
-
33646201684
-
Functional bowel disorders
-
Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130:1480-91.
-
(2006)
Gastroenterology
, vol.130
, pp. 1480-1491
-
-
Longstreth, G.F.1
Thompson, W.G.2
Chey, W.D.3
Houghton, L.A.4
Mearin, F.5
Spiller, R.C.6
-
16
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
-
Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes. 1994;43:535-9.
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhoj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
17
-
-
74049143227
-
A catalogue of reporting guidelines for health research
-
Simera I, Moher D, Hoey J, Schulz KF, Altman DG. A catalogue of reporting guidelines for health research. Eur J Clin Invest. 2010;40:35-53.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 35-53
-
-
Simera, I.1
Moher, D.2
Hoey, J.3
Schulz, K.F.4
Altman, D.G.5
-
18
-
-
33846863146
-
Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis
-
Nicholls SJ, Tuzcu EM, Sipahi I, Grasso AW, Schoenhagen P, Hu T, et al. Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis. JAMA. 2007;297:499-508.
-
(2007)
JAMA
, vol.297
, pp. 499-508
-
-
Nicholls, S.J.1
Tuzcu, E.M.2
Sipahi, I.3
Grasso, A.W.4
Schoenhagen, P.5
Hu, T.6
Wolski, K.7
Crowe, T.8
Desai, M.Y.9
Hazen, S.L.10
-
19
-
-
79960842622
-
Constipation and risk of cardiovascular disease among postmenopausal women
-
Salmoirago-Blotcher E, Crawford S, Jackson E, Ockene J, Ockene I. Constipation and risk of cardiovascular disease among postmenopausal women. Am J Med. 2011;124:714-23.
-
(2011)
Am J Med
, vol.124
, pp. 714-723
-
-
Salmoirago-Blotcher, E.1
Crawford, S.2
Jackson, E.3
Ockene, J.4
Ockene, I.5
-
20
-
-
34247586805
-
Health hazards in middle-aged women with cardiovascular disease: a case-control study of swedish women. the women's health in the Lund area (WHILA) study
-
Shakir YA, Samsioe G, Khatibi EA, Nyberg P, Lidfeldt J, Agardh CD, et al. Health hazards in middle-aged women with cardiovascular disease: a case-control study of swedish women. the women's health in the Lund area (WHILA) study. J Womens Health (Larchmt). 2007;16:406-14.
-
(2007)
J Womens Health (Larchmt)
, vol.16
, pp. 406-414
-
-
Shakir, Y.A.1
Samsioe, G.2
Khatibi, E.A.3
Nyberg, P.4
Lidfeldt, J.5
Agardh, C.D.6
Nerbrand, C.7
-
21
-
-
0032816659
-
Bile acids and lipoprotein metabolism: a renaissance for bile acids in the post-statin era?
-
Angelin B, Eriksson M, Rudling M. Bile acids and lipoprotein metabolism: a renaissance for bile acids in the post-statin era? Curr Opin Lipid. 1999;10:269-74.
-
(1999)
Curr Opin Lipid
, vol.10
, pp. 269-274
-
-
Angelin, B.1
Eriksson, M.2
Rudling, M.3
-
22
-
-
56749182268
-
Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation
-
Abrahamsson H, Ostlund-Lindqvist AM, Nilsson R, Simren M, Gillberg PG. Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation. Scand J Gastroenterol. 2008;43:1483-8.
-
(2008)
Scand J Gastroenterol
, vol.43
, pp. 1483-1488
-
-
Abrahamsson, H.1
Ostlund-Lindqvist, A.M.2
Nilsson, R.3
Simren, M.4
Gillberg, P.G.5
-
23
-
-
59849121662
-
Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients
-
Hofmann AF, Loening-Baucke V, Lavine JE, Hagey LR, Steinbach JH, Packard CA, et al. Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients. J Pediatr Gastroenterol Nutr. 2008;47:598-606.
-
(2008)
J Pediatr Gastroenterol Nutr
, vol.47
, pp. 598-606
-
-
Hofmann, A.F.1
Loening-Baucke, V.2
Lavine, J.E.3
Hagey, L.R.4
Steinbach, J.H.5
Packard, C.A.6
Griffin, T.L.7
Chatfield, D.A.8
-
24
-
-
84865313567
-
Increased bile acid biosynthesis is associated with irritable bowel syndrome with diarrhea
-
Wong BS, Camilleri M, Carlson P, McKinzie S, Busciglio I, Bondar O, et al. Increased bile acid biosynthesis is associated with irritable bowel syndrome with diarrhea. Clin Gastroenterol Hepatol. 2012;10:1009-15. e1003.
-
(2012)
Clin Gastroenterol Hepatol
, vol.10
, pp. 1009-1015
-
-
Wong, B.S.1
Camilleri, M.2
Carlson, P.3
McKinzie, S.4
Busciglio, I.5
Bondar, O.6
Dyer, R.B.7
Lamsam, J.8
Zinsmeister, A.R.9
-
25
-
-
79953321818
-
The association of bile acid excretion and atherosclerotic coronary artery disease
-
Charach G, Grosskopf I, Rabinovich A, Shochat M, Weintraub M, Rabinovich P. The association of bile acid excretion and atherosclerotic coronary artery disease. Therap Adv Gastroenterol. 2011;4:95-101.
-
(2011)
Therap Adv Gastroenterol
, vol.4
, pp. 95-101
-
-
Charach, G.1
Grosskopf, I.2
Rabinovich, A.3
Shochat, M.4
Weintraub, M.5
Rabinovich, P.6
-
26
-
-
84861682490
-
TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
-
Harach T, Pols TW, Nomura M, Maida A, Watanabe M, Auwerx J, et al. TGR5 potentiates GLP-1 secretion in response to anionic exchange resins. Sci Rep. 2012;2:430.
-
(2012)
Sci Rep
, vol.2
, pp. 430
-
-
Harach, T.1
Pols, T.W.2
Nomura, M.3
Maida, A.4
Watanabe, M.5
Auwerx, J.6
Schoonjans, K.7
-
27
-
-
77953403465
-
Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?
-
Knop FK. Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes? Am J Physiol Endocrinol Metab. 2010;299:E10-13.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E10-13
-
-
Knop, F.K.1
-
28
-
-
78449274342
-
Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
-
Migoya EM, Bergeron R, Miller JL, Snyder RN, Tanen M, Hilliard D, et al. Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. Clin Pharmacol Ther. 2010;88:801-8.
-
(2010)
Clin Pharmacol Ther
, vol.88
, pp. 801-808
-
-
Migoya, E.M.1
Bergeron, R.2
Miller, J.L.3
Snyder, R.N.4
Tanen, M.5
Hilliard, D.6
Weiss, B.7
Larson, P.8
Gutierrez, M.9
Jiang, G.10
-
29
-
-
77249142314
-
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
-
Shang Q, Saumoy M, Holst JJ, Salen G, Xu G. Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. Am J Physiol Gastrointest Liver Physiol. 2010;298:G419-424.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.298
, pp. G419-424
-
-
Shang, Q.1
Saumoy, M.2
Holst, J.J.3
Salen, G.4
Xu, G.5
-
30
-
-
83455243025
-
Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes
-
Chen L, Yao X, Young A, McNulty J, Anderson D, Liu Y, et al. Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am J Physiol Endocrinol Metab. 2012;302:E68-76.
-
(2012)
Am J Physiol Endocrinol Metab
, vol.302
, pp. E68-76
-
-
Chen, L.1
Yao, X.2
Young, A.3
McNulty, J.4
Anderson, D.5
Liu, Y.6
Nystrom, C.7
Croom, D.8
Ross, S.9
Collins, J.10
-
31
-
-
54249157393
-
Novel pathways for glycaemic control in type 2 diabetes: focus on bile acid modulation
-
Brinton EA. Novel pathways for glycaemic control in type 2 diabetes: focus on bile acid modulation. Diabetes Obes Metab. 2008;10:1004-11.
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 1004-1011
-
-
Brinton, E.A.1
-
32
-
-
0035955922
-
Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults
-
Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, Horowitz M. Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. Arch Intern Med. 2001;161:1989-96.
-
(2001)
Arch Intern Med
, vol.161
, pp. 1989-1996
-
-
Bytzer, P.1
Talley, N.J.2
Leemon, M.3
Young, L.J.4
Jones, M.P.5
Horowitz, M.6
-
33
-
-
0038408886
-
Risk factors for chronic constipation based on a general practice sample
-
Talley NJ, Jones M, Nuyts G, Dubois D. Risk factors for chronic constipation based on a general practice sample. Am J Gastroenterol. 2003;98:1107-11.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 1107-1111
-
-
Talley, N.J.1
Jones, M.2
Nuyts, G.3
Dubois, D.4
|