Significance of the changes occurring in the levels of interleukins, SOD and MDA in rat pulmonary tissue following exposure to different altitudes and exposure times

Experimental and Therapeutic Medicine

Volumn 10, Issue 3, 2015, Pages 915-920

  Yuhai, Gu ^a   Zhen, Zhao ^a  

^a Department of Respiratory Medicine Qinghai Provincial People s Hospital   (China)

Author keywords

Different altitudes and exposure times; Interleukin; Malondialdehyde; Rat pulmonary tissue; Superoxide dismutase

Indexed keywords

BILE ACID; CYTOKINE; HEMOGLOBIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ALTITUDE; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CELL PROLIFERATION ASSAY; COLORIMETRY; CONTROLLED STUDY; ENVIRONMENTAL CHANGE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPOXIA; LUNG PARENCHYMA; MALE; NONHUMAN; PNEUMONIA; RAT; TIME;

EID: 84937678826     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2604     Document Type: Article

References (21)

1. Opal SM and DePalo VA: Anti-inflammatory cytokines. Chest 117: 1162-1172, 2000.
2. Li A, Dubey S, Varney ML, Dave BJ and Singh RK: IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170: 3369-3376, 2003.
3. Hilgenberg E, Shen P, Dang VD, Ries S, Sakwa I and Fillatreau S: Interleukin-10-producing B cells and the regulation of immunity. Curr Top Microbiol Immunol 380: 69-92, 2014.
4. Hofmann SR, Rösen-Wolff A, Tsokos GC and Hedrich CM: Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury. Clin Immunol 143: 116-127, 2012.
5. Seyhan N and Canseven AG: In vivo effects of ELF MFs on collagen synthesis, free radical processes, natural antioxidant system, respiratory burst system, immune system activities, and electrolytes in the skin, plasma, spleen, lung, kidney, and brain tissues. Electromagn Biol Med 25: 291-305, 2006.
6. Niki E: Lipid peroxidation products as oxidative stress biomarkers. Biofactors 34: 171-180, 2008.
7. Sarada S, Himadri P, Mishra C, Geetali P, Ram MS and Ilavazhagan G: Role of oxidative stress and NFkB in hypoxiainduced pulmonary edema. Exp Biol Med (Maywood) 233: 1088-1098, 2008.
8. Kubo K, Hanaoka M, Yamaguchi S, Hayano T, Hayasaka M, Koizumi T, Fujimoto K, Kobayashi T and Honda T: Cytokines in bronchoalveolar lavage fluid in patients with high altitude pulmonary oedema at moderate altitude in Japan. Thorax 51: 739-742, 1996.
9. Heffner JE and Repine JE: Pulmonary strategies of antioxidant defense. Am Rev Respir Dis 140: 531-554, 1989.
10. Bulger EM and Maier RV: Antioxidants in critical illness. Arch Surg 136: 1201-1207, 2001.
11. Nakanishi K, Tajima F, Nakamura A, Yagura S, Ookawara T, Yamashita H, Suzuki K, Taniguchi N, Ohno H: Effects of hypobaric hypoxia on antioxidant enzymes in rats. J Physiol 489: 869-876, 1995.
12. Diehl S and Rincón M: The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 39: 531-536, 2002.
13. Packard RR and Libby P: Inflammation in atherosclerosis: From vascular biology to biomarker discovery and risk prediction. Clin Chem 54: 24-38, 2008.
14. Akira S, Taga T and Kishimoto T: Interleukin-6 in biology and medicine. Adv Immunol 54: 1-78, 1993.
15. Remick DG: Interleukin-8. Crit Care Med 33 (Suppl 12): S466-S467, 2005.
16. Waugh DJ and Wilson C: The interleukin-8 pathway in cancer. Clin Cancer Res 14: 6735-6741, 2008.
17. Delogu G, Antonucci A, Signore M, Marandola M, Tellan G and Ippoliti F: Plasma levels of IL-10 and nitric oxide under two different anaesthesia regimens. Eur J Anaesthesiol 22: 462-466, 2005.
18. Miller BJ, Buckley P, Seabolt W, Mellor A and Kirkpatrick B: Meta-analysis of cytokine alterations in schizophrenia: Clinical status and antipsychotic effects. Biol Psychiatry 70: 663-671, 2011.
19. Moore KW, de Waal Malefyt R, Coffman RL and O'Garra A: Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19: 683-765, 2001.
20. Suzer T, Coskun E, Demir S and Tahta K: Lipid peroxidation and glutathione levels after cortical injection of ferric chloride in rats: effect of trimetazidine and deferoxamine. Res Exp Med (Berl) 199: 223-229, 2000.
21. Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR and Grandjean P: Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 43: 1209-1214, 1997.