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Volumn 166, Issue 2, 2015, Pages 176-187

Evidence for metabolic aberrations in asymptomatic persons with type 2 diabetes after initiation of simvastatin therapy

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; CREATINE KINASE; LOW DENSITY LIPOPROTEIN; SIMVASTATIN; UBIQUINONE; MESSENGER RNA;

EID: 84937634884     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2015.01.007     Document Type: Article
Times cited : (4)

References (45)
  • 2
    • 33845306820 scopus 로고    scopus 로고
    • Statin-induced apoptosis and skeletal myopathy
    • A.J. Dirks, and K.M. Jones Statin-induced apoptosis and skeletal myopathy Am J Physiol Cell Physiol 291 2006 C1208 C1212
    • (2006) Am J Physiol Cell Physiol , vol.291 , pp. C1208-C1212
    • Dirks, A.J.1    Jones, K.M.2
  • 3
    • 36148966971 scopus 로고    scopus 로고
    • Statin myopathy: Incidence, risk factors, and pathophysiology
    • K.A. Sewright, P.M. Clarkson, and P.D. Thompson Statin myopathy: incidence, risk factors, and pathophysiology Curr Atheroscler Rep 9 2007 389 396
    • (2007) Curr Atheroscler Rep , vol.9 , pp. 389-396
    • Sewright, K.A.1    Clarkson, P.M.2    Thompson, P.D.3
  • 4
    • 34248195476 scopus 로고    scopus 로고
    • Endogenous synthesis of coenzyme Q in eukaryotes
    • U.C. Tran, and C.F. Clarke Endogenous synthesis of coenzyme Q in eukaryotes Mitochondrion 7 suppl 2007 S62 S71
    • (2007) Mitochondrion , vol.7 , pp. S62-S71
    • Tran, U.C.1    Clarke, C.F.2
  • 5
    • 23644449084 scopus 로고    scopus 로고
    • The effect of HMG-CoA reductase inhibitors on coenzyme Q10: Possible biochemical/clinical implications
    • I.P. Hargreaves, A.J. Duncan, S.J. Heales, and J.M. Land The effect of HMG-CoA reductase inhibitors on coenzyme Q10: possible biochemical/clinical implications Drug Saf 28 2005 659 676
    • (2005) Drug Saf , vol.28 , pp. 659-676
    • Hargreaves, I.P.1    Duncan, A.J.2    Heales, S.J.3    Land, J.M.4
  • 6
    • 34249826635 scopus 로고    scopus 로고
    • The role of coenzyme Q10 in statin-associated myopathy: A systematic review
    • L. Marcoff, and P.D. Thompson The role of coenzyme Q10 in statin-associated myopathy: a systematic review J Am Coll Cardiol 49 2007 2231 2237
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2231-2237
    • Marcoff, L.1    Thompson, P.D.2
  • 7
    • 21844435776 scopus 로고    scopus 로고
    • High-dose statins and skeletal muscle metabolism in humans: A randomized, controlled trial
    • H. Paiva, K.M. Thelen, R. Van Coster, and et al. High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial Clin Pharmacol Ther 78 2005 60 68
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 60-68
    • Paiva, H.1    Thelen, K.M.2    Van Coster, R.3
  • 8
    • 84872044673 scopus 로고    scopus 로고
    • Simvastatin effects on skeletal muscle: Relation to decreased mitochondrial function and glucose intolerance
    • S. Larsen, N. Stride, M. Hey-Mogensen, and et al. Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance J Am Coll Cardiol 61 2013 44 53
    • (2013) J Am Coll Cardiol , vol.61 , pp. 44-53
    • Larsen, S.1    Stride, N.2    Hey-Mogensen, M.3
  • 9
    • 26944451510 scopus 로고    scopus 로고
    • Muscle coenzyme Q10 level in statin-related myopathy
    • C. Lamperti, A.B. Naini, V. Lucchini, and et al. Muscle coenzyme Q10 level in statin-related myopathy Arch Neurol 62 2005 1709 1712
    • (2005) Arch Neurol , vol.62 , pp. 1709-1712
    • Lamperti, C.1    Naini, A.B.2    Lucchini, V.3
  • 10
    • 0030607116 scopus 로고    scopus 로고
    • Plasma ubiquinol/cholesterol ratios in patients with hyperlipidaemia, those with diabetes mellitus and in patients requiring dialysis
    • M.G. McDonnell, and G.P. Archbold Plasma ubiquinol/cholesterol ratios in patients with hyperlipidaemia, those with diabetes mellitus and in patients requiring dialysis Clin Chim Acta 253 1996 117 126
    • (1996) Clin Chim Acta , vol.253 , pp. 117-126
    • McDonnell, M.G.1    Archbold, G.P.2
  • 11
    • 0032924222 scopus 로고    scopus 로고
    • Effect of treatment with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on serum coenzyme Q10 in diabetic patients
    • Y. Miyake, A. Shouzu, M. Nishikawa, and et al. Effect of treatment with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on serum coenzyme Q10 in diabetic patients Arzneimittelforschung 49 1999 324 329
    • (1999) Arzneimittelforschung , vol.49 , pp. 324-329
    • Miyake, Y.1    Shouzu, A.2    Nishikawa, M.3
  • 12
    • 79959428660 scopus 로고    scopus 로고
    • Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: A meta-analysis
    • D. Preiss, S.R. Seshasai, P. Welsh, and et al. Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis JAMA 305 2011 2556 2564
    • (2011) JAMA , vol.305 , pp. 2556-2564
    • Preiss, D.1    Seshasai, S.R.2    Welsh, P.3
  • 13
    • 77549087054 scopus 로고    scopus 로고
    • Statins and risk of incident diabetes: A collaborative meta-analysis of randomised statin trials
    • N. Sattar, D. Preiss, H.M. Murray, and et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials Lancet 375 2010 735 742
    • (2010) Lancet , vol.375 , pp. 735-742
    • Sattar, N.1    Preiss, D.2    Murray, H.M.3
  • 14
    • 84868091600 scopus 로고    scopus 로고
    • Statins and risk of new-onset diabetes mellitus
    • R.V. Shah, and A.B. Goldfine Statins and risk of new-onset diabetes mellitus Circulation 126 2012 30 e282 e284
    • (2012) Circulation , vol.126 , pp. e282-e284
    • Shah, R.V.1    Goldfine, A.B.2
  • 15
    • 85027957106 scopus 로고    scopus 로고
    • Lipid-lowering therapies, glucose control and incident diabetes: Evidence, mechanisms and clinical implications
    • B. Zafrir, and M. Jain Lipid-lowering therapies, glucose control and incident diabetes: evidence, mechanisms and clinical implications Cardiovasc Drugs Ther 28 2014 361 367
    • (2014) Cardiovasc Drugs Ther , vol.28 , pp. 361-367
    • Zafrir, B.1    Jain, M.2
  • 16
    • 75149194772 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in diabetes: From molecular mechanisms to functional significance and therapeutic opportunities
    • W.I. Sivitz, and M.A. Yorek Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities Antioxid Redox Signal 12 2010 537 577
    • (2010) Antioxid Redox Signal , vol.12 , pp. 537-577
    • Sivitz, W.I.1    Yorek, M.A.2
  • 17
    • 63149173251 scopus 로고    scopus 로고
    • Standards of medical care in diabetes - 2009
    • Standards of medical care in diabetes - 2009 Diabetes Care 32 suppl 1 2009 S13 S61
    • (2009) Diabetes Care , vol.32 , pp. S13-S61
  • 18
    • 0023838119 scopus 로고
    • Calculation of metabolic expenditure and substrate utilization from gas exchange measurements
    • D.R. Westenskow, C.A. Schipke, J.L. Raymond, and et al. Calculation of metabolic expenditure and substrate utilization from gas exchange measurements JPEN J Parenter Enteral Nutr 12 1988 20 24
    • (1988) JPEN J Parenter Enteral Nutr , vol.12 , pp. 20-24
    • Westenskow, D.R.1    Schipke, C.A.2    Raymond, J.L.3
  • 19
    • 18644383865 scopus 로고    scopus 로고
    • Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress
    • M. Merlo Pich, A. Castagnoli, A. Biondi, and et al. Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress Free Radic Res 36 2002 429 436
    • (2002) Free Radic Res , vol.36 , pp. 429-436
    • Merlo Pich, M.1    Castagnoli, A.2    Biondi, A.3
  • 20
    • 84878233512 scopus 로고    scopus 로고
    • Mitochondrial function in diabetes: Novel methodology and new insight
    • L. Yu, B.D. Fink, J.A. Herlein, and W.I. Sivitz Mitochondrial function in diabetes: novel methodology and new insight Diabetes 62 2013 1833 1842
    • (2013) Diabetes , vol.62 , pp. 1833-1842
    • Yu, L.1    Fink, B.D.2    Herlein, J.A.3    Sivitz, W.I.4
  • 21
    • 1542709444 scopus 로고    scopus 로고
    • Simultaneous analysis of coenzyme Q10 in plasma, erythrocytes and platelets: Comparison of the antioxidant level in blood cells and their environment in healthy children and after oral supplementation in adults
    • P. Niklowitz, T. Menke, W. Andler, and J.G. Okun Simultaneous analysis of coenzyme Q10 in plasma, erythrocytes and platelets: comparison of the antioxidant level in blood cells and their environment in healthy children and after oral supplementation in adults Clin Chim Acta 342 2004 219 226
    • (2004) Clin Chim Acta , vol.342 , pp. 219-226
    • Niklowitz, P.1    Menke, T.2    Andler, W.3    Okun, J.G.4
  • 22
    • 33947655852 scopus 로고    scopus 로고
    • Gene expression profiling in the early phases of DMD: A constant molecular signature characterizes DMD muscle from early postnatal life throughout disease progression
    • M. Pescatori, A. Broccolini, C. Minetti, and et al. Gene expression profiling in the early phases of DMD: a constant molecular signature characterizes DMD muscle from early postnatal life throughout disease progression FASEB J 21 2007 1210 1226
    • (2007) FASEB J , vol.21 , pp. 1210-1226
    • Pescatori, M.1    Broccolini, A.2    Minetti, C.3
  • 23
    • 84902367750 scopus 로고    scopus 로고
    • Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis
    • X. Suarez-Calvet, E. Gallardo, G. Nogales-Gadea, and et al. Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis J Pathol 233 2014 258 268
    • (2014) J Pathol , vol.233 , pp. 258-268
    • Suarez-Calvet, X.1    Gallardo, E.2    Nogales-Gadea, G.3
  • 24
    • 79958072409 scopus 로고    scopus 로고
    • MRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass
    • S.D. Kunkel, M. Suneja, S.M. Ebert, and et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass Cell Metab 13 2011 627 638
    • (2011) Cell Metab , vol.13 , pp. 627-638
    • Kunkel, S.D.1    Suneja, M.2    Ebert, S.M.3
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 9244240769 scopus 로고    scopus 로고
    • Trends in cardiovascular complications of diabetes
    • C.S. Fox, S. Coady, P.D. Sorlie, and et al. Trends in cardiovascular complications of diabetes JAMA 292 2004 2495 2499
    • (2004) JAMA , vol.292 , pp. 2495-2499
    • Fox, C.S.1    Coady, S.2    Sorlie, P.D.3
  • 27
    • 84902576469 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines
    • N.J. Stone, J. Robinson, A.H. Lichtenstein, and et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines J Am Coll Cardiol 63 2013 2889 2934
    • (2013) J Am Coll Cardiol , vol.63 , pp. 2889-2934
    • Stone, N.J.1    Robinson, J.2    Lichtenstein, A.H.3
  • 28
    • 84857239563 scopus 로고    scopus 로고
    • Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins
    • P. Sirvent, O. Fabre, S. Bordenave, and et al. Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins Toxicol Appl Pharmacol 259 2012 263 268
    • (2012) Toxicol Appl Pharmacol , vol.259 , pp. 263-268
    • Sirvent, P.1    Fabre, O.2    Bordenave, S.3
  • 29
    • 0029837064 scopus 로고    scopus 로고
    • Lipid-lowering drugs and mitochondrial function: Effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio
    • G. De Pinieux, P. Chariot, M. Ammi-Said, and et al. Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio Br J Clin Pharmacol 42 1996 333 337
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 333-337
    • De Pinieux, G.1    Chariot, P.2    Ammi-Said, M.3
  • 30
    • 14844327531 scopus 로고    scopus 로고
    • Simvastatin triggers mitochondria-induced Ca2+ signaling alteration in skeletal muscle
    • P. Sirvent, J. Mercier, G. Vassort, and A. Lacampagne Simvastatin triggers mitochondria-induced Ca2+ signaling alteration in skeletal muscle Biochem Biophys Res Commun 329 2005 1067 1075
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 1067-1075
    • Sirvent, P.1    Mercier, J.2    Vassort, G.3    Lacampagne, A.4
  • 31
    • 0028831354 scopus 로고
    • Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans
    • R. Laaksonen, K. Jokelainen, T. Sahi, M.J. Tikkanen, and J.J. Himberg Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans Clin Pharmacol Ther 57 1995 62 66
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 62-66
    • Laaksonen, R.1    Jokelainen, K.2    Sahi, T.3    Tikkanen, M.J.4    Himberg, J.J.5
  • 32
    • 0030012771 scopus 로고    scopus 로고
    • The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle
    • R. Laaksonen, K. Jokelainen, J. Laakso, and et al. The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle Am J Cardiol 77 1996 851 854
    • (1996) Am J Cardiol , vol.77 , pp. 851-854
    • Laaksonen, R.1    Jokelainen, K.2    Laakso, J.3
  • 33
    • 0028661076 scopus 로고
    • Exogenous CoQ10 supplementation prevents plasma ubiquinone reduction induced by HMG-CoA reductase inhibitors
    • A.M. Bargossi, G. Grossi, P.L. Fiorella, A. Gaddi, R. Di Giulio, and M. Battino Exogenous CoQ10 supplementation prevents plasma ubiquinone reduction induced by HMG-CoA reductase inhibitors Mol Aspects Med 15 suppl 1994 s187 s193
    • (1994) Mol Aspects Med , vol.15 , pp. s187-s193
    • Bargossi, A.M.1    Grossi, G.2    Fiorella, P.L.3    Gaddi, A.4    Di Giulio, R.5    Battino, M.6
  • 34
    • 84880864181 scopus 로고    scopus 로고
    • Simvastatin impairs exercise training adaptations
    • C.R. Mikus, L.J. Boyle, S.J. Borengasser, and et al. Simvastatin impairs exercise training adaptations J Am Coll Cardiol 62 2013 709 714
    • (2013) J Am Coll Cardiol , vol.62 , pp. 709-714
    • Mikus, C.R.1    Boyle, L.J.2    Borengasser, S.J.3
  • 36
    • 78650438176 scopus 로고    scopus 로고
    • Evaluation of skeletal muscle during calf exercise by 31-phosphorus magnetic resonance spectroscopy in patients on statin medications
    • J.S. Wu, C. Buettner, H. Smithline, L.H. Ngo, and R.L. Greenman Evaluation of skeletal muscle during calf exercise by 31-phosphorus magnetic resonance spectroscopy in patients on statin medications Muscle Nerve 43 2011 76 81
    • (2011) Muscle Nerve , vol.43 , pp. 76-81
    • Wu, J.S.1    Buettner, C.2    Smithline, H.3    Ngo, L.H.4    Greenman, R.L.5
  • 39
    • 77957221743 scopus 로고    scopus 로고
    • The impact of the extracellular matrix on inflammation
    • L. Sorokin The impact of the extracellular matrix on inflammation Nat Rev Immunol 10 2010 712 723
    • (2010) Nat Rev Immunol , vol.10 , pp. 712-723
    • Sorokin, L.1
  • 40
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • D.E. Kelley, J. He, E.V. Menshikova, and V.B. Ritov Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes Diabetes 51 2002 2944 2950
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 41
    • 34249720640 scopus 로고    scopus 로고
    • Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes
    • M. Mogensen, K. Sahlin, M. Fernstrom, and et al. Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes Diabetes 56 2007 1592 1599
    • (2007) Diabetes , vol.56 , pp. 1592-1599
    • Mogensen, M.1    Sahlin, K.2    Fernstrom, M.3
  • 42
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • E. Link, S. Parish, J. Armitage, and et al. SLCO1B1 variants and statin-induced myopathy - a genomewide study N Engl J Med 359 2008 789 799
    • (2008) N Engl J Med , vol.359 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 43
    • 9644252909 scopus 로고    scopus 로고
    • Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs
    • D.J. Graham, J.A. Staffa, D. Shatin, and et al. Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs JAMA 292 2004 2585 2590
    • (2004) JAMA , vol.292 , pp. 2585-2590
    • Graham, D.J.1    Staffa, J.A.2    Shatin, D.3
  • 44
    • 0019332724 scopus 로고
    • Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts
    • J.R. Faust, M.S. Brown, and J.L. Goldstein Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts J Biol Chem 255 1980 6546 6548
    • (1980) J Biol Chem , vol.255 , pp. 6546-6548
    • Faust, J.R.1    Brown, M.S.2    Goldstein, J.L.3
  • 45
    • 56549119551 scopus 로고    scopus 로고
    • Effects of ubiquinone (coenzyme Q10) on myopathy in statin users
    • C.F. Schaars, and A.F. Stalenhoef Effects of ubiquinone (coenzyme Q10) on myopathy in statin users Curr Opin Lipidol 19 2008 553 557
    • (2008) Curr Opin Lipidol , vol.19 , pp. 553-557
    • Schaars, C.F.1    Stalenhoef, A.F.2


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