Impact of a Genomic Classifier of Metastatic Risk on Postprostatectomy Treatment Recommendations by Radiation Oncologists and Urologists

Urology

Volumn 86, Issue 1, 2015, Pages 35-40

  Nguyen, Paul L ^a   Shin, Heesun ^b   Yousefi, Kasra ^b   Thompson, Darby J ^c   Hornberger, John ^d,e   Hyatt, Andrew S ^a   Badani, Ketan K ^f   Morgan, Todd M ^g   Feng, Felix Y ^h  

^a HARVARD MEDICAL SCHOOL   (United States)

^b GenomeDx Biosciences Inc   (Canada)

^c EMMES Canada   (Canada)

^d Cedar Associates LLC   (United States)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Department of Medicine   (United States)

^g UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^h UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER HORMONE THERAPY; CANCER RADIOTHERAPY; CANCER RISK; CLASSIFIER; CLINICAL ARTICLE; CONSULTATION; CONTROLLED STUDY; DISTANT METASTASIS; GENETIC RISK; GENOMIC CLASSIFIER; GENOMICS; HUMAN; MALE; MEDICAL INFORMATICS; MULTICENTER STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; PROSTATECTOMY; RADIATION ONCOLOGIST; RANDOMIZED CONTROLLED TRIAL; TERTIARY CARE CENTER; UROLOGIST; CLINICAL PRACTICE; CLINICAL TRIAL; METASTASIS; MIDDLE AGED; ONCOLOGY; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE CARE; PRACTICE GUIDELINE; PROCEDURES; PROSTATIC NEOPLASMS; SECONDARY; STANDARDS; UROLOGY;

GENOMICS; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; PHYSICIAN'S PRACTICE PATTERNS; POSTOPERATIVE CARE; PRACTICE GUIDELINES AS TOPIC; PROSPECTIVE STUDIES; PROSTATECTOMY; PROSTATIC NEOPLASMS; RADIATION ONCOLOGY; UROLOGY;

EID: 84937440521     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2015.04.004     Document Type: Article

References (17)

1. R.K. Valicenti, I. Thompson Jr., P. Albertsen, and et al. Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association Guidelines Int J Radiat Oncol Biol Phys 86 2013 822 828
2. S.P. Kim, J.C. Tilburt, R.J. Karnes, and et al. Variation in treatment recommendations of adjuvant radiation therapy for high-risk prostate cancer by physician specialty Urology 82 2013 807 813
3. M. Bolla, H. van Poppel, B. Tombal, and et al. Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911) Lancet 380 2012 2018 2027
4. I.M. Thompson, C.M. Tangen, J. Paradelo, and et al. Adjuvant radiotherapy for pathologically advanced prostate cancer: a randomized clinical trial JAMA 296 2006 2329 2335
5. T. Wiegel, D. Bottke, U. Steiner, and et al. Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95 J Clin Oncol 27 2009 2924 2930
6. A. Briganti, T. Wiegel, S. Joniau, and et al. Early salvage radiation therapy does not compromise cancer control in patients with pT3N0 prostate cancer after radical prostatectomy: results of a match-controlled multi-institutional analysis Eur Urol 62 2012 472 487
7. K.D. Sorensen, and T.F. Orntoft Discovery of prostate cancer biomarkers by microarray gene expression profiling Expert Rev Mol Diagn 10 2010 49 64
8. M. Gallucci, R. Merola, C. Leonardo, and et al. Genetic profile identification in clinically localized prostate carcinoma Urol Oncol 27 2009 502 508
9. J. Cuzick, G.P. Swanson, G. Fisher, and et al. Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study Lancet Oncol 12 2011 245 255
10. N. Erho, A. Crisan, I.A. Vergara, and et al. Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy PLoS One 8 2013 e66855
11. A.E. Ross, F.Y. Feng, M. Ghadessi, and et al. A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy Prostate Cancer Prostatic Dis 17 2014 64 69
12. R.J. Karnes, E.J. Bergstralh, E. Davicioni, and et al. Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk patient population J Urol 190 2013 2047 2053
13. R.D. Den, F.Y. Feng, T.N. Showalter, and et al. A genomic prostate cancer classifier predicts biochemical failure and metastasis in patients following post operative radiation therapy IJROBP 89 2014 1038 1046
14. K. Badani, D.J. Thompson, C. Buerki, and et al. Impact of a genomic classifier of metastatic risk on postoperative treatment recommendations for prostate cancer patients: a report from the DECIDE study group Oncotarget 4 2013 600 609
15. M.W. Kattan, C. Yu, L. Salomon, and et al. Development and validation of preoperative nomogram for disease recurrence within 5 years after laparoscopic radical prostatectomy for prostate cancer Urology 77 2011 396 401
16. S.E. Eggener, P.T. Scardino, P.C. Walsh, and et al. Predicting 15-year prostate cancer specific mortality after radical prostatectomy J Urol 185 2011 869 875
17. D.F. Penson Re: variation in treatment recommendations of adjuvant radiation therapy for high-risk prostate cancer by physician specialty J Urol 191 2014 658