The erosion of research integrity: The need for culture change

The Lancet Oncology

Volumn 16, Issue 7, 2015, Pages 752-754

  Ellis, Lee M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RESEARCH; CULTURAL FACTOR; GENE MUTATION; HUMAN; MEDICAL LITERATURE; MEDICAL RESEARCH; NEOPLASM; NOTE; ONCOLOGY; PRIORITY JOURNAL; PUBLICATION; REPRODUCIBILITY; TRANSLATIONAL RESEARCH; ETHICS; NEEDS ASSESSMENT; NEOPLASMS; ORGANIZATION AND MANAGEMENT; PHARMACEUTICS; SCIENTIFIC MISCONDUCT; STANDARDS; STATISTICS AND NUMERICAL DATA; TRENDS; UNITED STATES;

ANTINEOPLASTIC AGENT; NEW DRUG;

ANTINEOPLASTIC AGENTS; DRUGS, INVESTIGATIONAL; HUMANS; NEEDS ASSESSMENT; NEOPLASMS; SCIENTIFIC MISCONDUCT; TECHNOLOGY, PHARMACEUTICAL; TRANSLATIONAL MEDICAL RESEARCH; UNITED STATES;

EID: 84937432637     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(15)00085-6     Document Type: Note

References (12)

1. DiMasi JA, Reichert JM, Feldman L, Malins A Clinical approval success rates for investigational cancer drugs. Clin Pharmacol Ther 2013, 94:329-335.
2. Khanna I Drug discovery in pharmaceutical industry: productivity challenges and trends. Drug Discov Today 2012, 17:1088-1102.
3. Prinz F, Schlange T, Asadullah K Believe it or not: how much can we rely on published data on potential drug targets?. Nat Reviews Drug Discovery 2011, 10:712.
4. Begley CG, Ellis LM Drug development: raise standards for preclinical cancer research. Nature 2012, 483:531-533.
5. Mobley A, Linder SK, Braeuer R, Ellis LM, Zwelling L A survey on data reproducibility in cancer research provides insights into our limited ability to translate findings from the laboratory to the clinic. PLoS One 2013, 8:e63221.
6. Slavov N Papers that truiumphed over their rejections. Aug 15, 2014 (accessed June 4, 2015). https://majesticforest.wordpress.com/2014/08/15/papers-that-triumphed-over-their-rejections/.
7. Pickett C A new reproducibility initiative at the NIH (accessed June 4, 2015). http://www.asbmb.org/asbmbtoday/201402/NewsFromTheHill/.
8. Casadevall A, Fang FC Causes for the persistence of impact factor mania. mBio 2014, 5:e00064-e00114.
9. Fang FC, Casadevall A Retracted science and the retraction index. Infect Immun 2011, 79:3855-3859.
10. Sample I Nobel winner declares boycott of top science journals (accessed June 4, 2015). http://www.theguardian.com/science/2013/dec/09/nobel-winner-boycott-science-journals.
11. Cyranoski D, Gilbert N, Ledford H, Nayar A, Yahia M The PhD factory. Nature 2011, 472:276-279.
12. Announcement: reducing our irreproducibility. Nature 2013, 496:398.