Incidence of stroke and seizure in Alzheimer's disease dementia

Age and Ageing

Volumn 44, Issue 4, 2015, Pages 695-699

  Cook, Michael ^a   Baker, Nicole ^a   Lanes, Stephen ^b   Bullock, Roger ^c   Wentworth, Charles ^c   Michael Arrighi, H ^d  

^a PFIZER INC   (United States)

^b Healthcore   (United States)

^c Janssen Research and Development LLC ^*  (United States)

^d JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Alzheimer's disease; Database; Older people; Seizures; Stroke; THIN

Indexed keywords

ADULT; AGE; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEIZURE; UNITED KINGDOM; VERY ELDERLY; COMPLICATION; ELECTRONIC HEALTH RECORD; FOLLOW UP; GERIATRIC ASSESSMENT; GREAT BRITAIN; HEALTH SURVEY; PROCEDURES; RISK FACTOR; SEIZURES; STROKE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ELECTRONIC HEALTH RECORDS; FEMALE; FOLLOW-UP STUDIES; GERIATRIC ASSESSMENT; GREAT BRITAIN; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POPULATION SURVEILLANCE; RETROSPECTIVE STUDIES; RISK FACTORS; SEIZURES; STROKE;

EID: 84937411095     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afv061     Document Type: Article

References (12)

1. de la Torre JC. Alzheimer disease as a vascular disorder: no sological evidence. Stroke 2002; 33: 1152-62.
2. Drzezga A, Lautenschlager N, Siebner H et al. Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study. Eur J Nucl Med Mol Imaging 2003; 30: 1104-13.
3. Jellinger KA. Prevalence and impact of cerebrovascular lesions in Alzheimer and lewy body diseases. Neurodegener Dis 2010; 7: 112-5.
4. Lee C-W, Shih Y-H, Kuo Y-M. Cerebrovascular pathology and amyloid plaque formation in Alzheimer's disease. Curr Alzheimer Res 2014; 11: 4-10.
5. Tolppanen A, Lavikainen P, Solomon A, Kivipelto M, Soininen H, Hartikainen S. Incidence of stroke in people with Alzheimer disease. Neurology 2013; 80: 353-8.
6. Chi NF, Chien LN, Ku HL, Hu CJ, Chiou HY. Alzheimer disease and risk of stroke: a population-based cohort study. Neurology 2013; 80: 705-11.
7. Amatniek JC, Hauser WA, DelCastillo-Castaneda C et al. Incidence and predictors of seizures in patients with Alzheimer's disease. Epilepsia 2006; 47: 867-72.
8. Scarmeas N, Honig LS, Choi H et al. Seizures in Alzheimer disease: who, when and how common? Arch Neurol 2009; 66: 992-7.
9. Jellinger KA. Alzheimer disease and cerebrovascular pathology: an update. J Neural Transm 2002; 109: 813-36.
10. Richard E, Gouw AA, Scheltens P, van Gool WA. Vascular care in patients with Alzheimer disease with cerebrovascular lesions slows progression of white matter lesions on MRI: the evaluation of vascular care in Alzheimer's disease (EVA) study. Stroke 2010; 41: 554-6.
11. Strozyk D, Dickson DW, Lipton RB et al. Contribution of vascular pathology to the clinical expression of dementia. Neurobiol Aging 2010; 31: 1710-20.
12. Zipp F, Aktas O. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases. Trend Neurosci 2006; 29: 518-27.