Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

Journal of the American College of Cardiology

Volumn 66, Issue 3, 2015, Pages 261-272

  Zhang, Min ^a   Prosser, Benjamin L ^b   Bamboye, Moradeke A ^c   Gondim, Antonio N S ^c   Santos, Celio X ^a   Martin, Daniel ^a   Ghigo, Alessandra ^d   Perino, Alessia ^d   Brewer, Alison C ^a   Ward, Christopher W ^c   Hirsch, Emilio ^d   Lederer, W Jonathan ^c   Shah, Ajay M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

angiotensin II; contraction; myocyte; NADPH oxidase

Indexed keywords

ANGIOTENSIN II; CALCIUM ION; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; CALCIUM; CALCIUM BINDING PROTEIN; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE OVERLOAD; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; ANIMAL; BIOLOGICAL MODEL; CARDIOVASCULAR DISEASE; DISEASE MODEL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRANSGENIC MOUSE;

ANGIOTENSIN II; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CARDIOVASCULAR DISEASES; DISEASE MODELS, ANIMAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NADPH OXIDASE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RENIN-ANGIOTENSIN SYSTEM; SARCOPLASMIC RETICULUM;

EID: 84937406257     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.05.020     Document Type: Article

References (28)

1. 2+ handling in heart failure Circ Res 113 2013 690 708
2. A.V. Zima, and L.A. Blatter Redox regulation of cardiac calcium channels and transporters Cardiovasc Res 71 2006 310 321
3. D.I. Brown, and K.K. Griendling Nox proteins in signal transduction Free Radic Biol Med 47 2009 1239 1253
4. M. Zhang, A.C. Brewer, K. Schröder, and et al. NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis Proc Natl Acad Sci U S A 107 2010 18121 18126
5. C. Heymes, J.K. Bendall, P. Ratajczak, and et al. Increased myocardial NADPH oxidase activity in human heart failure J Am Coll Cardiol 41 2003 2164 2171
6. C. Maack, T. Kartes, H. Kilter, and et al. Oxygen free radical release in human failing myocardium is associated with increased activity of Rac1-GTPase and represents a target for statin treatment Circulation 108 2003 1567 1574
7. J.R. Erickson, M.L. Joiner, X. Guan, and et al. A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation Cell 133 2008 462 474
8. phox for left ventricular remodeling/dysfunction and survival after myocardial infarction Circ Res 100 2007 894 903
9. phox-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice Circulation 105 2002 293 296
10. M. Zhang, A. Perino, A. Ghigo, E. Hirsch, and A.M. Shah NADPH oxidases in heart failure: poachers or gamekeepers? Antioxid Redox Signal 18 2013 1024 1041
11. B.L. Prosser, C.W. Ward, and W.J. Lederer X-ROS signaling: rapid mechano-chemo transduction in heart Science 333 2011 1440 1445
12. B.L. Prosser, C.W. Ward, and W.J. Lederer X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch Cardiovasc Res 98 2013 307 314
13. H.S. Kim, M.C. Song, I.H. Kwak, T.J. Park, and I.K. Lim Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence J Biol Chem 278 2003 37497 37510
14. O.H.K. Cingolani, and D.A. Kass Pressure-volume relation analysis of mouse ventricular function Am J Physiol 301 2011 H2198 H2206
15. - and systolic blood pressure in mice Circ Res 89 2001 408 414
16. A. Mattiazzi, C. Mundiña-Weilenmann, C. Guoxiang, L. Vittone, and E. Kranias Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions Cardiovasc Res 68 2005 366 375
17. E.G. Kranias, and R.J. Hajjar Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome Circ Res 110 2012 1646 1660
18. X.H.T. Wehrens, S.E. Lehnart, S. Reiken, J.A. Vest, A. Wronska, and A.R. Marks Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression Proc Natl Acad Sci U S A 103 2006 511 518
19. J.R. Burgoyne, H. Mongue-Din, P. Eaton, and A.M. Shah Redox signaling in cardiac physiology and pathology Circ Res 111 2012 1091 1106
20. N.A.E. Steenaart, J.R. Ganim, J. Di Salvo, and E.G. Kranias The phospholamban phosphatase associated with cardiac sarcoplasmic reticulum is a type 1 enzyme Arch Biochem Biophys 293 1992 17 24
21. J.M. Li, N.P. Gall, D.J. Grieve, M. Chen, and A.M. Shah Activation of NADPH oxidase during progression of cardiac hypertrophy to failure Hypertension 40 2002 477 484
22. M. Wang, J. Zhang, S.J. Walker, R. Dworakowski, E.G. Lakatta, and A.M. Shah Involvement of NADPH oxidase in age-associated cardiac remodeling J Mol Cell Cardiol 48 2010 765 772
23. 2+ entry during the slow force response J Mol Cell Cardiol 63 2013 37 46
24. J. Palomeque, L. Sapia, R.J. Hajjar, A. Mattiazzi, and M. Vila Petroff Angiotensin II-induced negative inotropy in rat ventricular myocytes: role of reactive oxygen species and p38 MAPK Am J Physiol 290 2006 H96 H106
25. D.C. Lefroy, T. Crake, F. Del Monte, and et al. Angiotensin II and contraction of isolated myocytes from human, Guinea pig, and infarcted rat hearts Am J Physiol 270 1996 H2060 H2069
26. 2, a necessary evil for cell signaling Science 312 2006 1882 1883
27. N.K. Tonks Redox redux: revisiting PTPs and the control of cell signaling Cell 121 2005 667 670
28. T.C. Herzig, S.M. Jobe, H. Aoki, and et al. Angiotensin II type 1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload Proc Natl Acad Sci U S A 94 1997 7543 7548