Assessing phage therapy against Pseudomonas aeruginosa using a Galleria mellonella infection model

International Journal of Antimicrobial Agents

Volumn 46, Issue 2, 2015, Pages 196-200

  Beeton, M L ^a   Alves, D R ^b   Enright, M C ^c   Jenkins, A T A ^b  

^a CARDIFF METROPOLITAN UNIVERSITY   (United Kingdom)

^b University of Bath   (United Kingdom)

^c MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Galleria mellonella; Infection model; Phage therapy; Pseudomonas aeruginosa

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIAL COUNT; BACTERIAL STRAIN; BACTERIOPHAGE; BACTERIUM ISOLATE; CONTROLLED STUDY; GALLERIA MELLONELLA; HEMOLYMPH; INFECTION PREVENTION; LARVA; NONHUMAN; PHAGE THERAPY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; SURVIVAL RATE; ANIMAL; BIOLOGICAL THERAPY; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; LEPIDOPTERA; MICROBIOLOGY; PHYSIOLOGY; PROCEDURES; PSEUDOMONAS INFECTIONS; PSEUDOMONAS PHAGE; SURVIVAL; VIROLOGY;

ANIMALS; BIOLOGICAL THERAPY; DISEASE MODELS, ANIMAL; HEMOLYMPH; HUMANS; LEPIDOPTERA; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; PSEUDOMONAS PHAGES; SURVIVAL ANALYSIS;

EID: 84937252221     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2015.04.005     Document Type: Article

References (18)

1. H.W. Boucher, G.H. Talbot, J.S. Bradley, J.E. Edwards, D. Gilbert, L.B. Rice, and et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America Clin Infect Dis 48 2009 1 12
2. F. Barbier, and M. Wolff Multi-drug resistant Pseudomonas aeruginosa: towards a therapeutic dead end? [in French] Med Sci (Paris) 26 2010 960 968
3. A. Oliver, and A. Mena Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance Clin Microbiol Infect 16 2010 798 808
4. T.L. Pitt, M. Sparrow, M. Warner, and M. Stefanidou Survey of resistance of Pseudomonas aeruginosa from UK patients with cystic fibrosis to six commonly prescribed antimicrobial agents Thorax 58 2003 794 796
5. J. Emerson, M. Rosenfeld, S. McNamara, B. Ramsey, and R.L. Gibson Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis Pediatr Pulmonol 34 2002 91 100
6. T.M. Viertel, K. Ritter, and H.P. Horz Viruses versus bacteria - novel approaches to phage therapy as a tool against multidrug-resistant pathogens J Antimicrob Chemother 69 2014 2326 2336
7. M. Bedi, V. Verma, and S. Chhibber Amoxicillin and specific bacteriophage can be used together for eradication of biofilm of Klebsiella pneumoniae B5055 World J Microbiol Biotechnol 25 2009 1145 1151
8. A.Y. Peleg, D. Monga, S. Pillai, E. Mylonakis, R.C. Moellering Jr., and G.M. Eliopoulos Reduced susceptibility to vancomycin influences pathogenicity in Staphylococcus aureus infection J Infect Dis 199 2009 532 536
9. A. Bruttin, and H. Brussow Human volunteers receiving Escherichia coli phage T4 orally: a safety test of phage therapy Antimicrob Agents Chemother 49 2005 2874 2878
10. L. Dethlefsen, S. Huse, M.L. Sogin, and D.A. Relman The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing PLoS Biol 6 2008 e280
11. V.D. Paul, S. Sundarrajan, S.S. Rajagopalan, S. Hariharan, N. Kempashanaiah, S. Padmanabhan, and et al. Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection BMC Microbiol 11 2011 195
12. R. Abbasifar, A.M. Kropinski, P.M. Sabour, J.R. Chambers, J. MacKinnon, T. Malig, and et al. Efficiency of bacteriophage therapy against Cronobacter sakazakii in Galleria mellonella (greater wax moth) larvae Arch Virol 159 2014 2253 2261
13. F. Kamal, and J.J. Dennis Burkholderia cepacia complex phage-antibiotic synergy (PAS): antibiotics stimulate lytic phage activity Appl Environ Microbiol 81 2015 1132 1138
14. K.D. Seed, and J.J. Dennis Experimental bacteriophage therapy increases survival of Galleria mellonella larvae infected with clinically relevant strains of the Burkholderia cepacia complex Antimicrob Agents Chemother 53 2009 2205 2208
15. M. Giannouli, A.T. Palatucci, V. Rubino, G. Ruggiero, M. Romano, M. Triassi, and et al. Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori BMC Microbiol 14 2014 228
16. T.M. Gibreel, and M. Upton Synthetic epidermicin NI01 can protect Galleria mellonella larvae from infection with Staphylococcus aureus J Antimicrob Chemother 68 2013 2269 2273
17. A.Y. Peleg, S. Jara, D. Monga, G.M. Eliopoulos, R.C. Moellering Jr., and E. Mylonakis E. Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeutics Antimicrob Agents Chemother 53 2009 2605 2609
18. A.A. Angus, A.A. Lee, D.K. Augustin, E.J. Lee, D.J. Evans, and S.M. Fleiszig Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility Infect Immun 76 2008 1992 2001