Accurate measurement of the essential micronutrients methionine, homocysteine, vitamins B6, B12, B9 and their metabolites in plasma, brain and maternal milk of mice using LC/MS ion trap analysis

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 998-999, Issue , 2015, Pages 106-113

  Oosterink, J Efraim ^a   Naninck, Eva F G ^b   Korosi, Aniko ^b   Lucassen, Paul J ^b   van Goudoever, Johannes B ^a,c   Schierbeek, Henk ^a,c  

^a EMMA CHILDREN S HOSPITAL   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

B vitamins; Ion trap mass spectrometry; Methylation; Stable isotopes

Indexed keywords

ALKYLATION; AMINO ACIDS; CLINICAL RESEARCH; IONS; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; METABOLITES; METHYLATION; TRACE ELEMENTS; VITAMINS;

B-VITAMINS; EPIGENETIC MECHANISMS; ION-TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LOWER LIMITS OF QUANTITATIONS; PROTEIN PRECIPITATION; SIMULTANEOUS MEASUREMENT; STABLE ISOTOPES;

NUTRIENTS;

CYANOCOBALAMIN; HOMOCYSTEINE; METHIONINE; PYRIDOXINE; UNCLASSIFIED DRUG; VITAMIN B GROUP; VITAMIN B9; FOLIC ACID; TRACE ELEMENT;

ARTICLE; BLOOD LEVEL; BRAIN LEVEL; BREAST MILK; DEGRADATION; INFANT; ION TRAP MASS SPECTROMETRY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; ANIMAL; BLOOD; BRAIN CHEMISTRY; C57BL MOUSE; CHEMISTRY; EVALUATION STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; MILK; PROCEDURES;

MUS;

ANIMALS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; FOLIC ACID; HOMOCYSTEINE; MALE; MASS SPECTROMETRY; METHIONINE; MICE; MICE, INBRED C57BL; MICRONUTRIENTS; MILK; VITAMIN B 12; VITAMIN B 6;

EID: 84937231915     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2015.07.008     Document Type: Article

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