-
1
-
-
84906772173
-
Prediction of binding affinity and efficacy of thyroid hormone receptor ligands using QSAR and structure-based modeling methods
-
R. Politi I. Rusyn A. Tropsha Prediction of binding affinity and efficacy of thyroid hormone receptor ligands using QSAR and structure-based modeling methods Toxicol. Appl. Pharmacol. 280 2014 177 189
-
(2014)
Toxicol. Appl. Pharmacol.
, vol.280
, pp. 177-189
-
-
Politi, R.1
Rusyn, I.2
Tropsha, A.3
-
2
-
-
2942596255
-
Thyroid receptor ligands. Part 2: thyromimetics with improved selectivity for the thyroid hormone receptor beta
-
J.J. Hangeland A.M. Doweyko T. Dejneka T.J. Friends P. Devasthale K. Mellström J. Sandberg M. Grynfarb J.S. Sack H. Einspahr M. Färnegårdh B. Husman J. Ljunggren K. Koehler C. Sheppard J. Malm D.E. Ryono Thyroid receptor ligands. Part 2: thyromimetics with improved selectivity for the thyroid hormone receptor beta Bioorg. Med. Chem. Lett. 14 2004 3549 3553
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 3549-3553
-
-
Hangeland, J.J.1
Doweyko, A.M.2
Dejneka, T.3
Friends, T.J.4
Devasthale, P.5
Mellström, K.6
Sandberg, J.7
Grynfarb, M.8
Sack, J.S.9
Einspahr, H.10
Färnegårdh, M.11
Husman, B.12
Ljunggren, J.13
Koehler, K.14
Sheppard, C.15
Malm, J.16
Ryono, D.E.17
-
3
-
-
47349124043
-
Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands
-
S. Raval P. Raval D. Bandyopadhyay K. Soni D. Yevale D. Jogiya H. Modi A. Joharapurkar N. Gandhi M.R. Jain P.R. Patel Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands Bioorg. Med. Chem. Lett. 18 2008 3919 3924
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 3919-3924
-
-
Raval, S.1
Raval, P.2
Bandyopadhyay, D.3
Soni, K.4
Yevale, D.5
Jogiya, D.6
Modi, H.7
Joharapurkar, A.8
Gandhi, N.9
Jain, M.R.10
Patel, P.R.11
-
4
-
-
84925185989
-
Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists
-
T.P. Burkholder B.E. Cunningham J.R. Clayton P.A. Lander M.L. Brown R.A. Doti G.L. Durst C. Montrose-Rafizadeh C. King H.E. Osborne R.M. Amos R.W. Zink L.E. Stramm T.P. Burris G. Cardona D.L. Konkol C. Reidy M.E. Christe M.J. Genin Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists Bioorg. Med. Chem. Lett. 25 2015 1377 1380
-
(2015)
Bioorg. Med. Chem. Lett.
, vol.25
, pp. 1377-1380
-
-
Burkholder, T.P.1
Cunningham, B.E.2
Clayton, J.R.3
Lander, P.A.4
Brown, M.L.5
Doti, R.A.6
Durst, G.L.7
Montrose-Rafizadeh, C.8
King, C.9
Osborne, H.E.10
Amos, R.M.11
Zink, R.W.12
Stramm, L.E.13
Burris, T.P.14
Cardona, G.15
Konkol, D.L.16
Reidy, C.17
Christe, M.E.18
Genin, M.J.19
-
5
-
-
76549096834
-
Establishment of yeast reporter assay systems to detect ligands of thyroid hormone receptors α and β
-
K. Shiizaki S. Asai S. Ebata M. Kawanishi T. Yagi Establishment of yeast reporter assay systems to detect ligands of thyroid hormone receptors α and β Toxicol. Vitro 24 2010 638 644
-
(2010)
Toxicol. Vitro
, vol.24
, pp. 638-644
-
-
Shiizaki, K.1
Asai, S.2
Ebata, S.3
Kawanishi, M.4
Yagi, T.5
-
7
-
-
84861335165
-
A QSAR study for modeling of thyroid receptors β1 selective ligands by application of adaptive neuro-fuzzy inference system and radial basis function
-
G. Azimi S. Afiuni-Zadeh A. Karami A QSAR study for modeling of thyroid receptors β1 selective ligands by application of adaptive neuro-fuzzy inference system and radial basis function J. Chemom. 26 2012 135 142
-
(2012)
J. Chemom.
, vol.26
, pp. 135-142
-
-
Azimi, G.1
Afiuni-Zadeh, S.2
Karami, A.3
-
9
-
-
0023965741
-
SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules
-
D. Weininger SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules J. Chem. Inf. Comput. Sci.® 28 1988 31 36
-
(1988)
J. Chem. Inf. Comput. Sci.®
, vol.28
, pp. 31-36
-
-
Weininger, D.1
-
11
-
-
0000144425
-
Smiles. 3. Depict. Graphical depiction of chemical structures
-
D. Weininger Smiles. 3. Depict. Graphical depiction of chemical structures J. Chem. Information Comput. Sci. 30 1990 237 243
-
(1990)
J. Chem. Information Comput. Sci.
, vol.30
, pp. 237-243
-
-
Weininger, D.1
-
14
-
-
84909979851
-
Optimal descriptor as a translator of eclectic data into prediction of cytotoxicity for metal oxide nanoparticles under different conditions
-
A.P. Toropova A.A. Toropov R. Rallo D. Leszczynska J. Leszczynski Optimal descriptor as a translator of eclectic data into prediction of cytotoxicity for metal oxide nanoparticles under different conditions Ecotoxicol. Environ. Saf. 112 2015 39 45
-
(2015)
Ecotoxicol. Environ. Saf.
, vol.112
, pp. 39-45
-
-
Toropova, A.P.1
Toropov, A.A.2
Rallo, R.3
Leszczynska, D.4
Leszczynski, J.5
-
15
-
-
84937200348
-
-
accessed 30.04.15
-
REACH 2007 http://ec.europa.eu/environment/chemicals/reach/reach-intro.htm accessed 30.04.15
-
(2007)
REACH
-
-
|