Effect of low-intensity physical activity and moderate- to high-intensity physical exercise during adjuvant chemotherapy on physical fitness, fatigue, and chemotherapy completion rates: Results of the PACES randomized clinical trial

Journal of Clinical Oncology

Volumn 33, Issue 17, 2015, Pages 1918-1927

  Van Waart, Hanna ^a   Stuiver, Martijn M ^a   Van Harten, Wim H ^a   Geleijn, Edwin ^b   Kieffer, Jacobien M ^a   Buffart, Laurien M ^b,c   De Maaker Berkhof, Marianne ^a   Boven, Epie ^b   Schrama, Jolanda ^f   Geenen, Maud M ^d,i   Meerum Terwogt, Jetske M ^d   Van Bochove, Aart ^g,h   Lustig, Vera ⁱ   Van Den Heiligenberg, Simone M ^g,j   Smorenburg, Carolien H ^k   Hellendoorn van Vreeswijk, Jeannette A J H ^e   Sonke, Gabe S ^a   Aaronson, Neil K ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

^e Integraal Kankercentrum Amsterdam   (Netherlands)

^f Infection and Immunology   (Netherlands)

^g Medical Oncology   (Netherlands)

^h ZAANS MEDICAL CENTER   (Netherlands)

ⁱ Flevo Hospital   (Netherlands)

^j Westfries Gasthuis   (Netherlands)

^k Location Alkmaar   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; TRASTUZUMAB;

ADJUVANT CHEMOTHERAPY; ADULT; AEROBIC EXERCISE; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; CANCER ADJUVANT THERAPY; CARDIORESPIRATORY FITNESS; COLON CANCER; DISTRESS SYNDROME; EXERCISE; FATIGUE; FEMALE; FITNESS; FOLLOW UP; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUSCLE STRENGTH; NAUSEA AND VOMITING; PARTIAL MASTECTOMY; PHYSICAL ACTIVITY; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SELF REPORT; SLEEP QUALITY; AGED; BREAST NEOPLASMS; CHEMICALLY INDUCED; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DRUG ADMINISTRATION; HEALTH STATUS; KINESIOTHERAPY; MOTOR ACTIVITY; NAUSEA; PAIN; TREATMENT OUTCOME; VOMITING;

ACTIVITIES OF DAILY LIVING; ADULT; AGED; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; DRUG ADMINISTRATION SCHEDULE; EXERCISE; EXERCISE THERAPY; FATIGUE; FEMALE; FOLLOW-UP STUDIES; HEALTH STATUS; HUMANS; MIDDLE AGED; MOTOR ACTIVITY; MUSCLE STRENGTH; NAUSEA; PAIN; PHYSICAL FITNESS; QUALITY OF LIFE; SELF REPORT; TRASTUZUMAB; TREATMENT OUTCOME; VOMITING;

EID: 84937112287     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.59.1081     Document Type: Article

References (44)

1. Early Breast Cancer Trialists' Collaborative Group, Peto R, Davies C, et al: Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. Lancet 379:432-444, 2012
2. Courneya KS: Exercise in cancer survivors: An overview of research. Med Sci Sports Exerc 35:1846-1852, 2003
3. Hartvig P, Aulin J, Hugerth M, et al: Fatigue in cancer patients treated with cytotoxic drugs. J Oncol Pharm Pract 12:155-164, 2006
4. Cheema B, Gaul CA, Lane K, et al: Progressive resistance training in breast cancer: A systematic review of clinical trials. Breast Cancer Res Treat 109:9-26, 2008
5. Galvão DA, Newton RU: Review of exercise intervention studies in cancer patients. J Clin Oncol 23:899-909, 2005
6. Knols R, Aaronson NK, Uebelhart D, et al: Physical exercise in cancer patients during and after medical treatment: A systematic review of randomized and controlled clinical trials. J Clin Oncol 23:3830-3842, 2005
7. Kuchinski AM, Reading M, Lash AA: Treatment-related fatigue and exercise in patients with cancer: A systematic review. Medsurg Nurs 18:174-180, 2009
8. Mishra SI, Scherer RW, Snyder C, et al: Exercise interventions on health-related quality of life for people with cancer during active treatment. Cochrane Database Syst Rev 8:CD008465, 2012
9. Courneya KS, McKenzie DC, Mackey JR, et al: Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial. J Natl Cancer Inst 105:1821-1832, 2013
10. Baumann FT, Bloch W, Weissen A, et al: Physical activity in breast cancer patients during medical treatment and in the aftercare: A review. Breast Care (Basel) 8:330-334, 2013
11. Courneya KS, Segal RJ, Mackey JR, et al: Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial. J Clin Oncol 25:4396-4404, 2007
12. Mock V, Cameron L, Tompkins C, et al: Every Step Counts: A Walking Exercise Program for Persons With Cancer. Baltimore, MD, John Hopkins University, 1997
13. Velthuis MJ, Agasi-Idenburg SC, Aufdemkampe G, et al: The effect of physical exercise on cancer-related fatigue during cancer treatment: A meta-analysis of randomised controlled trials. Clin Oncol (R Coll Radiol) 22:208-221, 2010
14. Van Waart H, Stuiver MM, van Harten WH, et al: Design of the Physical exercise during Adjuvant Chemotherapy Effectiveness Study (PACES): A randomized controlled trial to evaluate effectiveness and cost-effectiveness of physical exercise in improving physical fitness and reducing fatigue. BMC Cancer 10:673, 2010
15. Scott NW, McPherson GC, Ramsay CR, et al: The method of minimization for allocation to clinical trials: A review. Control Clin Trials 23:662-674, 2002
16. van der Ploeg HP, Streppel KR, van der Beek a J, et al: Counselling increases physical activity behaviour nine weeks after rehabilitation. Br J Sports Med 40:223-229, 2006
17. Borg G: Borg's Perceived Exertion and Pain Scales. Champaign, IL, Human Kinetics, 1998
18. Geleijn E, Smeets C, Vrijman M, et al: Cyto-Fys, behoud van kracht en uithoudingsvermogen tijdens chemotherapie. Ned Tijdschr voor Oncol 8:80-86, 2011
19. De Backer IC, Schep G, Hoogeveen A, et al: Exercise testing and training in a cancer rehabilitation program: The advantage of the steep ramp test. Arch Phys Med Rehabil 88:610-616, 2007
20. van der Ploeg RJ, Fidler V, Oosterhuis HJ: Hand-held myometry: Reference values. J Neurol Neurosurg Psychiatry 54:244-247, 1991
21. Knols RH, Aufdemkampe G, de Bruin ED, et al: Hand-held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength. BMC Musculoskelet Disord 10:31, 2009
22. Trutschnigg B, Kilgour RD, Reinglas J, et al: Precision and reliability of strength (Jamar vs. Biodex handgrip) and body composition (dual-energy X-ray absorptiometry vs. bioimpedance analysis) measurements in advanced cancer patients. Appl Physiol Nutr Metab 33:1232-1239, 2008
23. Jones C, Rikli R, Beam W: A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Q Exerc Sport 70:113-119, 1999
24. Smets EM, Garssen B, Bonke B, et al: The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res 39:315-325, 1995
25. Gielissen MF, Knoop H, Servaes P, et al: Differences in the experience of fatigue in patients and healthy controls: Patients' descriptions. Health Qual Life Outcomes 5:36, 2007
26. Chinapaw MJ, Buffart LM, van Mechelen W, et al: Alpe d'HuZes cancer rehabilitation (A-CaRe) research: Four randomized controlled exercise trials and economic evaluations in cancer patients and survivors. Int J Behav Med 19:143-156, 2012
27. Cohen J: Statistical Power Analysis for the Behavioral Sciences (ed 2). London, UK, Routledge, 1988
28. Twisk JWR: Applied Longitudinal Data Analysis for Epidemiology: A Practical Guide (ed 2). Cambridge, UK, Cambridge University Press, 2013
29. Morris S: Estimating effect sizes from pretest-posttest-control group designs. Organ Res Meth 11:364-386, 2008
30. Norman GR, Sloan JA, Wyrwich KW: Interpretation of changes in health-related quality of life: The remarkable universality of half a standard deviation. Med Care 41:582-592, 2003
31. Segal R, Evans W, Johnson D, et al: Structured exercise improves physical functioning in women with stages I and II breast cancer: Results of a randomized controlled trial. J Clin Oncol 19:657-665, 2001
32. Kim CJ, Kang D-H, Smith BA, et al: Cardiopulmonary responses and adherence to exercise in women newly diagnosed with breast cancer undergoing adjuvant therapy. Cancer Nurs 29:156-165, 2006
33. Lakoski SG, Eves ND, Douglas PS, et al: Exercise rehabilitation in patients with cancer. Nat Rev Clin Oncol 9:288-296, 2013
34. Peteet JR: Cancer and the meaning of work. Gen Hosp Psychiatry 22:200-205, 2000
35. Courneya KS, Segal RJ, McKenzie DC, et al: Effects of exercise during adjuvant chemotherapy on breast cancer outcomes. Med Sci Sports Exerc 46:1744-1751, 2014
36. Wonders KY, Reigle BS: Trastuzumab and doxorubicin-related cardiotoxicity and the cardioprotective role of exercise. Integr Cancer Ther 8:17-21, 2009
37. de Azambuja E, Procter MJ, van Veldhuisen DJ, et al: Trastuzumab-associated cardiac events at 8 years of median follow-up in the Herceptin Adjuvant trial (BIG 1-01). J Clin Oncol 32:2159-2165, 2014
38. Ong KC, Chong WF, Soh C, et al: Comparison of different exercise tests in assessing outcomes of pulmonary rehabilitation. Respir Care 49:1498-1503, 2004
39. Hornsby WE, Douglas PS, West MJ, et al: Safety and efficacy of aerobic training in operable breast cancer patients receiving neoadjuvant chemotherapy: A phase II randomized trial. Acta Oncol 53:65-74, 2014
40. Sears SR, Stanton AL, Kwan L, et al: Recruitment and retention challenges in breast cancer survivorship research: Results from a multisite, randomized intervention trial in women with early stage breast cancer. Cancer Epidemiol Biomarkers Prev 12:1087-1090, 2003
41. Würtzen H, Dalton SO, Andersen KK, et al: Who participates in a randomized trial of mindfulness-based stress reduction (MBSR) after breast cancer? A study of factors associated with enrollment among Danish breast cancer patients. Psychooncology 22:1180-1185, 2013
42. Chinn DJ, White M, Howel D, et al: Factors associated with non-participation in a physical activity promotion trial. Public Health 120:309-319, 2006
43. von Wagner C, Knight K, Steptoe A, et al: Functional health literacy and health-promoting behaviour in a national sample of British adults. J Epidemiol Community Health 61:1086-1090, 2007
44. Courneya KS, Vardy J, Gill S, et al: Update on the Colon Health and Life-Long Exercise Change trial: A phase III study of the impact of an exercise program on disease-free survival in colon cancer survivors. Curr Colorectal Cancer Rep 2014