Hot off the Press: Subdissociative-dose Ketamine for Acute Pain in the Emergency Department

Academic Emergency Medicine

Volumn 22, Issue 7, 2015, Pages 887-889

  Drake, Aaran B ^a   Milne, William K ^b   Carpenter, Christopher R ^c  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FENTANYL; KETAMINE; MORPHINE; NARCOTIC ANALGESIC AGENT; PLACEBO;

ADVERSE OUTCOME; ARTICLE; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; EMERGENCY CARE; EMERGENCY WARD; HUMAN; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; VOMITING;

EID: 84937023677     PISSN: 10696563     EISSN: 15532712     Source Type: Journal    
DOI: 10.1111/acem.12705     Document Type: Article

References (15)

1. Cantril SV, Brown MD, Carlisle RJ, et al., Clinical policy: critical issues in prescribing of opioids for adult patients in the emergency department. Ann Emerg Med 2012; 60: 499-525.
2. Bijur PE, Esses D, Chang AK, Gallagher EJ,. Dosing and titration of IV opioid analgesics administered to ED patients in acute severe pain. Am J Emerg Med 2012; 30: 1241-4.
3. Green SM,. There is oligo-evidence for oligoanalgesia. Ann Emerg Med 2012; 60: 212-4.
4. Petrenko AB, Yamakura T, Baba H, Shimoji K,. The role of N-methyl-D-aspartate (NMDA) receptors in pain: a review. Anesth Analg 2003; 97: 1108-16.
5. Bell RF, Dahl JB, Moore RA, Kalso E,. Perioperative ketamine for acute post-operative pain: a quantitative and qualitative systematic review (Cochrane Review). Acta Anaesthesiol Scand 2005; 49: 1405-28.
6. Hocking G, Cousins MJ,. Ketamine in chronic pain management: an evidence-based review. Anesth Analg 2003; 97: 1730-9.
7. Sin B, Ternas T, Motov SM,. The use of subdissociative-dose ketamine for acute pain in the ED. Acad Emerg Med 2015; 22: 251-7.
8. Hartling L, Hamm M, Milne A, et al., Validity and inter-rater reliability testing of quality assessment instruments. Rockville (MD): Agency for Healthcare Research and Quality (US), 2012, Report No. 12-EHC039-EF.
9. Chinta SS, Schrock CR, McAllister JD, Jaffe DM, Liu J, Kennedy RM., Rapid administration technique of ketamine for pediatric forearm fracture reduction: a dose-finding study. Ann Emerg Med 2015; http://dx.doi.org/10.1016/j.annemergmed.2014.12.011 [Epub ahead of print].
10. Carstensen M, Møller AM,. Adding ketamine to morphine for intravenous patient-controlled analgesia for acute postoperative pain: a qualitative review of randomized trials. Br J Anaesth 2010; 104: 401-6.
11. Gurnani A, Sharma PK, Rautela RS, Bhattacharya A,. Analgesia for acute musculoskeletal trauma: low dose subcutaneous infusion of ketamine. Anaesth Intensive Care 1996; 24: 32-6.
12. Kennedy RM, Porter FL, Miller JP, Jaffe DM,. Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies. Pediatrics 1998; 102: 956-63.
13. Miller JP, Schauer SG, Ganem VJ, Bebarta VS,. Low dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial. Am J Emerg Med 2015; 33: 402-8.
14. Beaudoin FL, Lin C, Guan W, Merchant RC,. Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial. Acad Emerg Med 2014; 21: 1193-202.
15. Shojania KG, Sampson M, Ansari MT, Ji J, Doucette S, Moher D,. How quickly do systematic reviews go out of date? A survival analysis Ann Intern Med 2007; 147: 224-33.