Thoracic spinal cord lesions are influenced by the degree of cervical spine involvement in multiple sclerosis

Spinal Cord

Volumn 53, Issue 7, 2015, Pages 520-525

  Hua, L H ^a   Donlon, S L ^b   Sobhanian, M J ^c   Portner, S M ^c   Okuda, D T ^c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Neurological Institute   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN DAMAGE; CERVICAL SPINAL CORD INJURY; CERVICAL SPINE; CLINICAL FEATURE; DISEASE DURATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOPLEGIA; MULTIPLE SCLEROSIS; MYELOOPTIC NEUROPATHY; NERVE FIBER; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NEURITIS; PRIORITY JOURNAL; SPINAL CORD INJURY; THORACIC SPINAL CORD; THORACIC SPINAL CORD LESION; THORACIC SPINE; ADOLESCENT; AGED; CERVICAL SPINAL CORD; CROSS-SECTIONAL STUDY; MIDDLE AGED; PATHOLOGY; RISK; SPINAL CORD DISEASE; VERTEBRA; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; CERVICAL CORD; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; RISK; SPINAL CORD DISEASES; THORACIC VERTEBRAE; YOUNG ADULT;

EID: 84936986535     PISSN: 13624393     EISSN: 14765624     Source Type: Journal    
DOI: 10.1038/sc.2014.238     Document Type: Article

References (20)

1. Bot JCJ, Barkhof F, Lycklama à Nijeholt G, van Schaardenburg D, Voskuyl AE, Ader HJ et al. Differentiation of multiple sclerosis from other inflammatory disorders and cerebrovascular disease: value of spinal MR imaging. Radiology 2002; 223: 46-56.
2. Nijeholt GJ, van Walderveen MA, Castelijns JA, van Waesberghe JH, Polman C, Scheltens P et al. Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms. Brain J Neurol 1998; 121: 687-697.
3. Thorpe JW, Kidd D, Moseley IF, Thompson AJ, MacManus DG, Compston DA et al. Spinal MRI in patients with suspected multiple sclerosis and negative brain MRI. Brain 1996; 119: 709-714.
4. Okuda DT, Mowry EM, Cree BA, Crabtree EC, Goodin DS, Waubant E et al. Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome. Neurology 2011; 76: 686-692.
5. Okuda DT, Siva A, Kantarci O, Inglese M, Katz I, Tutuncu M et al. Radiologically isolated syndrome: 5-year risk for an initial clinical event. PloS One 2014; 9: e90509.
6. Patrucco L, Rojas JI, Cristiano E. Assessing the value of spinal cord lesions in predicting development of multiple sclerosis in patients with clinically isolated syndromes. J Neurol 2011; 259: 1317-1320.
7. Sombekke MH, Wattjes MP, Balk LJ, Nielsen JM, Vrenken H, Uitdehaag BM et al. Spinal cord lesions in patients with clinically isolated syndrome: a powerful tool in diagnosis and prognosis. Neurology 2013; 80: 69-75.
8. Bag AK, Patel BN, Osman S, Roberson GH. Clinico-radiologic profile of spinal cord multiple sclerosis in adults. Neuroradiol J 2011; 24: 511-518.
9. Tartaglino LM, Friedman DP, Flanders AE, Lublin FD, Knobler RL, Liem M. Multiple sclerosis in the spinal cord: MR appearance and correlation with clinical parameters. Radiology 1995; 195: 725-732.
10. Honig LS, Sheremata WA. Magnetic resonance imaging of spinal cord lesions in multiple sclerosis. J Neurol Neurosurg Psychiatry 1989; 52: 459-466.
11. Kidd D, Thorpe JW, Thompson AJ, Kendall BE, Moseley IF, MacManus DG et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology 1993; 43: 2632-2637.
12. Wiebe S, Lee DH, Karlik SJ, Hopkins M, Vandervoort MK, Wong CJ et al. Serial cranial and spinal cord magnetic resonance imaging in multiple sclerosis. Ann Neurol 1992; 32: 643-650.
13. Bot JCJ, Barkhof F, Polman CH, Lycklama A, Nijeholt GJ, de Groot V, Bergers E et al. Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination. Neurology 2004; 62: 226-233.
14. Mowry EM, Deen S, Malikova I, Pelletier J, Bacchetti P, Waubant E. The onset location of multiple sclerosis predicts the location of subsequent relapses. J Neurol Neurosurg Psychiatry 2008; 80: 400-403.
15. Filippi M, Colombo B, Rovaris M, Pereira C, Martinelli V, Comi G. A longitudinal magnetic resonance imaging study of the cervical cord in multiple sclerosis. J. Neuroimaging 1997; 7: 78-80.
16. Oh J, Saidha S, Chen M, Smith SA, Prince J, Jones C et al. Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis. Neurology 2013; 80: 540-547.
17. Evangelou N. Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions. Brain 2004; 128: 29-34.
18. Stankiewicz JM, Neema M, Alsop DC, Healy BC, Arora A, Buckle GJ et al. Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study. J Neurol Sci 2009; 279: 99-105.
19. O'Riordan JI, Losseff NA, Phatouros C, Thompson AJ, Moseley IF, MacManus DG et al. Asymptomatic spinal cord lesions in clinically isolated optic nerve, brain stem, and spinal cord syndromes suggestive of demyelination. J Neurol Neurosurg Psychiatry 1998; 64: 353-357.
20. Nair G, Absinta M, Reich DS. Optimized T1-MPRAGE Sequence for Better Visualization of Spinal Cord Multiple Sclerosis Lesions at 3T. Am J Neuroradiol 2013; 34: 2215-2222.