Galantamine-loaded PLGA nanoparticles, from nano-emulsion templating, as novel advanced drug delivery systems to treat neurodegenerative diseases

Nanoscale

Volumn 7, Issue 28, 2015, Pages 12076-12084

  Fornaguera, C ^a,b   Feiner Gracia, N ^a,b   Caldero G ^a,b   Garcia Celma M J ^b,c   Solans, C ^a,b  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; EMULSIFICATION; EMULSIONS; NANOPARTICLES; POLYMERS; TARGETED DRUG DELIVERY;

DRUG DELIVERY SYSTEM; ENCAPSULATION EFFICIENCY; INTRAVENOUS ADMINISTRATION; LOW ENERGY EMULSIFICATION; NANOPARTICLE PREPARATIONS; NEGATIVE SURFACE CHARGES; POLYMERIC NANOPARTICLES; SUSTAINED DRUG RELEASE;

NEURODEGENERATIVE DISEASES;

CHOLINESTERASE INHIBITOR; DRUG CARRIER; EMULSION; GALANTAMINE; LACTIC ACID; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

CHEMISTRY; EMULSION; HELA CELL LINE; HUMAN; METABOLISM; NEURODEGENERATIVE DISEASES;

CHOLINESTERASE INHIBITORS; DRUG CARRIERS; EMULSIONS; GALANTAMINE; HELA CELLS; HUMANS; LACTIC ACID; NANOPARTICLES; NEURODEGENERATIVE DISEASES; POLYGLYCOLIC ACID;

EID: 84936972869     PISSN: 20403364     EISSN: 20403372     Source Type: Journal    
DOI: 10.1039/c5nr03474d     Document Type: Article

References (50)

1. J. K. Sahni S. Doggui J. Ali S. Baboota L. Dao C. Ramassamy Neurotherapeutic applications of nanoparticles in Alzheimer's disease J. Controlled Release 2011 152 208 231
2. M. R. Farlow Pharmacokinetic Profiles of Current Therapies for Alzheimer's Disease: Implications for Switching to Galantamine Clin. Ther. 2001 23 A 13 24
3. G. Tosi R. A. Fano L. Bondioli L. Badiali R. Benassi F. Rivasi B. Ruozi F. Forni A. Vandelli Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier Nanomedicine 2011 6 3 423 436
4. A. V. Kabanov H. E. Gendelman Nanomedicine in the diagnosis and therapy of neurodegenerative disorders Prog. Polym. Sci. 2007 32 1054 1082
5. S. Lilienfeld Galantamine - a Novel Cholinergic Drug with a Unique Dual Mode of Action for the Treatment of Patients with Alzheimer's Disease CNS Drug Rev. 2006 8 2 159 176
6. M. Villaroya A. G. García J. Marco-Contelles M. G. López An uptade on the pharmacology of galantamine Expert Opin. Invest. Drugs 2007 16 2 1987 1998
7. M. Fazil S. Baboota J. K. Sahni J. Ali Nanotherapeutics for Alzheimer's disease (AD): Past, present and future J. Drug Targeting 2012 20 2 97 113
8. J. Todoroff R. Vanbever Fate of nanomedicines in the lungs Curr. Opin. Colloid Interface Sci. 2011 16 246 254
9. C. Vauthier K. Bouchemal Methods for the preparation and manufacture of polymeric nanoparticles Pharm. Res. 2009 26 5 1025 1058
10. B. Neha B. Ganesh K. Preeti Drug delivery to the brain using polymeric nanoparticles: a review Int. J. Pharm. Life Sci. 2013 2 3 107 132
11. C. Pinto Reis R. J. Neufeld A. J. Ribeiro F. Veiga Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles Nanomedicine 2006 2 1 8 21
12. C. Solans I. Solè Nano-emulsions: Formation by low-energy methods Curr. Opin. Colloid Interface Sci. 2012 17 246 254
13. N. Anton J. P. Benoit P. Saulnier Design and production of nanoparticles formulated from nano-emulsion templates-a review J. Controlled Release 2008 128 185 199
14. G. Calderó M. J. García-Celma C. Solans Formation of polymeric nano-emulsions by a low energy method and their use for nanoparticle preparation J. Colloid Interface Sci. 2011 353 406 411
15. T. Tadros P. Izquierdo J. Esquena C. Solans Formation and stability of nano-emulsions Adv. Colloid Interface Sci. 2004 108-109 303 318
16. C. Fornaguera M. Llinàs C. Solans G. Calderó Design and in vitro evaluation of biocompatible dexamethasone-loaded nanoparticle dispersions, obtained from nano-emulsions, for inhalatory therapy Colloids Surf., B 2015 125 1 58 64
17. C. Fornaguera S. Grijalvo M. Galán E. Fuentes-Paniagua F. J. de la Mata R. Gómez R. Eritja G. Calderó C. Solans Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides Int. J. Pharm. 2015 478 1 113 123
18. W. Yang J. I. Peters R. O. Williams Inhaled Nanoparticles - A Current Review Int. J. Pharm. 2008 356 239 247
19. V. Bhardwaj D. D. Ankola S. C. Gupta M. Schneider C. M. Lehr N. V. Kumar PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat Pharm. Res. 2009 26 11 2495 2503
20. K. Hirota T. Hasegawa T. Nakajima H. Inagawa C. Kohchi G. I. Soma K. Makino H. Terada Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis J. Controlled Release 2010 42 339 346
21. C. Gómez-Gaete N. Tsapis M. Besnard A. Bochot E. Fattal Encapsulation of dexamethasone into biodegradable polymeric nanoparticles Int. J. Pharm. 2007 331 153 159
22. A. Kumari S. Kumar Yadav S. C. Yadav Biodegradable polymeric nanoparticles based drug delivery systems Colloids Surf., B 2010 75 1 18
23. Y. Wang X. Gao S. Kuriyavar D. Bourne B. Grady K. Chen K. Dormer R. D. Kopke Incorporation, release and effectiveness of Dexamethasone in poly(lactic-co-glycolic acid) nanoparticles for inner ear drug delivery J. Nanotechnol. Eng. Med. 2011 2 1 304 310
24. D. Putnam C. A. Gentry D. W. Pack R. Langer Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini Proc. Natl. Acad. Sci. U. S. A. 2001 98 3 1200 1205
25. M. B. Hansen S. G. Nielsen K. Berk Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill J. Immunol. Methods 1989 119 2 203 210
26. F. Danhier E. Ansorena J. M. Silva R. Coco A. Le Breton V. Préat PLGA-based nanoparticles: An overview of biomedical applications J. Controlled Release 2012 161 505 522
27. Y.-C. Chen W.-Y. Hsieh W.-F. Lee D.-T. Zeng Effects of surface modification of PLGA-PEG-PLGA nanoparticles on loperamide delivery efficiency across the blood-brain barrier J. Biomater. Appl. 2011 27 7 909 922
28. O. Harush-Frenkel N. Debotton S. Benita Y. Altschuler Targeting of nanoparticles to the clathrin-mediated encodytic pathway Biochem. Biophys. Res. Commun. 2007 353 26 32
29. S. A. Kulkarni S. S. Feng Effects of particle size and surface modification on cellular uptake and biodistribution of polymeric nanoparticles for drug delivery Pharm. Res. 2013 30 2512 2522
30. R. H. Muller C. Jacobs O. Kayser Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future Adv. Drug Delivery Rev. 2001 47 1 3 19
31. A. A. Date N. Desai R. Dixit M. Nagarsenker Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances Nanomedicine 2010 5 10 1595 1616
32. Pubchem website
33. M. Mufamadi Y. Choonara P. Kumar G. Modi D. Naidoo D. van Vuuren V. Ndesendo L. du Toita S. E. Iyuke V. Pillay Ligand-functionalized nanoliposomes for targeted delivery of galanthamine Int. J. Pharm. 2013 448 267 281
34. B. Wilson M. K. Samantha K. Santhi K. P. S. Kumar M. Ramasamy B. Suresh Chitosan nanoparticles as a new delivery systems for the anti-Alzheimer drug tacrine Nanomed. Nanotechnol. Biol. Med. 2010 6 1 144 152
35. K. L. Lanctôt N. Herrmann K. K. Yau L. R. Khan B. A. Liu B. M. LouLou T. R. Einarson Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease: a meta-analysis CMAJ 2003 169 6 557 564
36. J. L. Cummings L. Schneider P. N. Tariot P. R. Kershaw W. Yuan Reduction of Behavioral Disturbances and Caregiver Distress by Galantamine in Patients With Alzheimer's Disease Am. J. Psychiatr. 2004 161 532 538
37. G. H. Suh H. YeonJung C. U. Lee B. H. Oh J. N. Bae H. Y. Jung Y. S. Ju B. K. Yeon J. Park I. Hong S. Choi J. H. Lee A Prospective, Double-Blind, Community-Controlled Comparison of Three Doses of Galantamine in the Treatment of Mild to Moderate Alzheimer's Disease in a Korean Population Clin. Ther. 2004 26 10 1608 1618
38. J. Nicolas S. Mura D. Brambilla N. Mackiewicz P. Couvreur Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery Chem. Soc. Rev. 2013 42 1147 1235
39. W. Hanson, Theoretical concepts. Handbook of dissolution testing, Pharmaceutical Technology Publications, Oregon, vol. 4, 1982
40. L. S. Morris R. M. Schulz Patient compliance - A review J. Clin. Pharm. Ther. 1992 17 283 295
41. C. Fornaguera G. Calderó M. Mitjans M. P. Vinardell C. Solans C. Vauthier Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies Nanoscale 2015 7 6045 6058
42. R. C. Rowe, P. J. Sheskey and S. C. Owen, Handbook of pharmaceutical excipients, Pharmaceutical-Press, London, 5th edn, 2006
43. W. Brown, Dynamic Light Scattering: The Method and Some Applications, Oxford University Press, New York, 1993
44. H. A. Lieberman, M. M. Rieger and G. S. Banker, Pharmaceutical Dosage Forms: Disperse Systems Marcel Dekker, New York, 1988
45. A. V. Delgado F. González-Caballero R. J. Hunter L. K. Koopal Measurement and interpretation of electrokinetic phenomena J. Colloid Interface Sci. 2007 309 194 224
46. J. Maláková M. Nobilis Z. Svoboda M. Lísa M. Holcapek J. Kvetina J. Klimes V. Palicka High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples J. Chromatogr., B: Biomed. Appl. 2007 853 265 274
47. G. Calderó M. Llinàs M. J. García-Celma C. Solans Studies on Controlled Release of Hydrophilic Drugs from W/O High Internal Phase Ratio Emulsions J. Pharm. Sci. 2010 99 2 701 711
48. W. I. Higuchi Analysis of data on the medicament release from ointments J. Pharm. Sci. 1962 51 8 802 804
49. G. L. Ellman K. D. Courtney V. Andres R. M. Featherstone A new and rapid colorimetric determination of acetylcholinesterase activity Biochem. Pharmacol. 1961 7 88 95
50. S. López J. Bastida F. Viladomat C. Codina Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts Life Sci. 2002 71 2521 2529