A Novel pathogenic mammalian orthoreovirus from diarrheic pigs and swine blood meal in the United States

mBio

Volumn 6, Issue 3, 2015, Pages 1-11

  Narayanappa, Athmaram Thimmasandra ^a   Sooryanarain, Harini ^a   Deventhiran, Jagadeeswaran ^a   Cao, Dianjun ^a   Venkatachalam, Backiyalakshmi Ammayappan ^a   Kambiranda, Devaiah ^b   LeRoith, Tanya ^a   Heffron, Connie Lynn ^a   Lindstrom, Nicole ^a   Hall, Karen ^a   Jobst, Peter ^a   Sexton, Cary ^c   Meng, Xiang Jin ^a   Elankumaran, Subbiah ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b FLORIDA A AND M UNIVERSITY   (United States)

^c Livestock Veterinary Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' UNTRANSLATED REGION; ACUTE GASTROENTERITIS; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; EMBRYO; GENE MAPPING; GENOTYPE; MAMMALIAN ORTHOREOVIRUS; MOLECULAR EVOLUTION; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PIG; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; THERMOSTABILITY; TRANSMISSION ELECTRON MICROSCOPY; UNITED STATES; VIRION; VIRUS IDENTIFICATION; VIRUS ISOLATION; VIRUS MORPHOLOGY; VIRUS PURIFICATION; ANIMAL; BLOOD; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; FECES; GENETICS; ISOLATION AND PURIFICATION; MAMMALIAN ORTHOREOVIRUS 3; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; SWINE DISEASE; VETERINARY; VIROLOGY; VIRUS CULTURE;

CORONAVIRUS; MAMMALIA; MAMMALIAN ORTHOREOVIRUS; MAMMALIAN ORTHOREOVIRUS 3; PORCINE EPIDEMIC DIARRHEA VIRUS; SUIDAE; SUS;

VIRUS RNA;

ANIMALS; BLOOD; CLUSTER ANALYSIS; DIARRHEA; FECES; MAMMALIAN ORTHOREOVIRUS 3; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SWINE; SWINE DISEASES; UNITED STATES; VIRUS CULTIVATION;

EID: 84936946261     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00593-15     Document Type: Article

References (48)

1. Mitchell D. 2014. Porcine epidemic diarrhea virus is nasty-and it could get worse. http://modernfarmer.com/2014/03/piglet-attacking-virus-get-worse/. Accessed 9 November 2014.
2. Kareim R. 2014. Virus kills millions of American pigs, pushing up pork prices. http://news.nationalgeographic.com/news/2014/05/140501-pigs-virus-meat-prices-food-science-health/. Accessed 9 November 2014.
3. Stevenson GW, Hoang H, Schwartz KJ, Burrough ER, Sun D, Madson D, Cooper VL, Pillatzki A, Gauger P, Schmitt BJ, Koster LG, Killian ML, Yoon KJ. 2013. Emergence of porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences. J Vet Diagn Invest 25:649-654. http://dx.doi.org/10.1177/1040638713501675.
4. Wang L, Byrum B, Zhang Y. 2014. Detection and genetic characterization of deltacoronavirus in pigs, Ohio, USA, 2014. Emerg Infect Dis 20: 1227-1230. http://dx.doi.org/10.3201/eid2007.140296.
5. Vlasova AN, Marthaler D, Wang Q, Culhane MR, Rossow KD, Rovira A, Collins J, Saif LJ. 2014. Distinct characteristics and complex evolution of PEDV strains, North America, May 2013-February 2014. Emerg Infect Dis 20:1620-1628. http://dx.doi.org/10.3201/eid2010.140491.
6. EFSA. 2014. Scientific opinion on porcine epidemic diarrhea and emerging porcine deltacoronavirus. EFSA J 12:3877. http://dx.doi.org/10.2903/ j.efsa.2014.3877.
7. USDA. 2014. Gain-report. 2014. Multiple PED outbreaks likely to impact pork production. http://gain.fas.usda.gov/Recent%20GAIN %20Publications /Multiple%20PED%20Outbreaks%20Likely %20to%20Impact%20Pork%20Production%20%20_Kiev_Ukraine_12-10-2014.pdf. Accessed 30 January 2015.
8. USDA. 2014. Reporting, herd monitoring and management of novel swine enteric coronavirus diseases, June 5 2014. wwwaphisusdagov/ newsroom/2014/06/pdf/secd_federal_orderpdf. Accessed 9 November 2014.
9. Attoui H, Mertens PPC, Becnel J, Belaganahalli S, Bergoin M, Brussaard CP, Chappell JD, Ciarlet M, del Vas M, Dermody TS, Dormitzer PR, Duncan R, Fang Q, Graham R, Guglielmi KM, Harding RM, Hillman B, Makkay A, Marzachì C, Matthijnssens J, Milne RG, Mohd Jaafar F, Mori H, Noordeloos AA, Omura T, Patton JT, Rao S, Maan M, Stoltz D, Suzuki N, Upadhyaya NM, Wei C, Zhou H. 2011. Orthoreovirus, Reoviridae, p 546-554. In King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ (ed), Virus taxonomy classification and nomenclature of viruses: ninth report of the International Committee on the Taxonomy of Viruses. Elsevier Academic Press, London, United Kingdom.
10. Tyler KL, Barton ES, Ibach ML, Robinson C, Campbell JA, O'Donnell SM, Valyi-Nagy T, Clarke P, Wetzel JD, Dermody TS. 2004. Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis. J Infect Dis. 189:1664-1675. http://dx.doi.org/10.1086/ 383129.
11. Dermody TS, Parker JSL, Sherry B. 2013. Orthoreoviruses, p 1304-1346. In Knipe DM, Howley PM (ed), Fields virology, 6th ed. Lippincott Williams, Philadelphia, PA.
12. Duncan R. 1999. Extensive sequence divergence and phylogenetic relationships between the fusogenic and nonfusogenic orthoreoviruses: a species proposal. Virology 260:316-328. http://dx.doi.org/10.1006/ viro.1999.9832.
13. Chapell JD, Goral MI, Rodgers SE, dePamphilis CW, Dermody TS. 1994. Sequence diversity within the reovirus S2 gene: reovirus genes reassort in nature, and their termini are predicted to form a panhandle motif. J Virol 68:750-756.
14. Ouattara LA, Barin F, Barthez MA, Bonnaud B, Roingeard P, Goudeau A, Castelnau P, Vernet G, Paranhos-Baccalà G, Komurian-Pradel F. 2011. Novel human reovirus isolated from children with acute necrotizing encephalopathy. Emerg Infect Dis 17:1436-1444. http://dx.doi.org/ 10.3201/eid1708.101528.
15. Baskerville A, McFerran JB, Connor T. 1971. The pathology of experimental infection of pigs with type I reovirus of porcine origin. Res Vet Sci 12:172-174.
16. Kasza L. 1970. Isolation and characterisation of a reovirus from pigs. Vet Rec 87:681-686. http://dx.doi.org/10.1136/vr.87.22.681.
17. Zhang C, Liu L, Wang P, Liu S, Lin W, Hu F, Wu W, Chen W, Cui S. 2011. A potentially novel reovirus isolated from swine in northeastern China in 2007. Virus Genes 43:342-349. http://dx.doi.org/10.1007/s11262-011-0642-4.
18. Kwon HJ, Kim HH, Kim HJ, Park JG, Son KY, Jung J, Lee WS, Cho KO, Park SJ, Kang MI. 2012. Detection and molecular characterization of porcine type 3 orthoreoviruses circulating in South Korea. Vet Microbiol 157:456-463. http://dx.doi.org/10.1016/j.vetmic.2011.12.032.
19. Chua KB, Voon K, Yu M, Keniscope C, Abdul Rasid K, Wang LF. 2011. Investigation of a potential zoonotic transmission of orthoreovirus associated with acute influenza-like illness in an adult patient. PLoS One 6:e25434. http://dx.doi.org/10.1371/journal.pone.0025434.
20. Kohl C, Lesnik R, Brinkmann A, Ebinger A, Radonić A, Nitsche A, Mühldorfer K, Wibbelt G, Kurth A. 2012. Isolation and characterization of three mammalian orthoreoviruses from European bats. PLoS One 7:e43106. http://dx.doi.org/10.1371/journal.pone.0043106.
21. Steyer A, Gutiérrez-Aguire I, Kolenc M, Koren S, Kutnjak D, Pokorn M, Poljšak-Prijatelj M, Racki N, Ravnikar M, Sagadin M, Fratnik Steyer A, Toplak N. 2013. High similarity of novel orthoreovirus detected in a child hospitalized with acute gastroenteritis to mammalian orthoreoviruses found in bats in Europe. J Clin Microbiol 51:3818-3825. http:// dx.doi.org/10.1128/JCM.01531-13.
22. USDA-APHIS. 2014. Swine enteric coronavirus disease. SECD: situation report-October 30, 2014. USDA-Animal and Plant Health Inspection Service, Washington, DC. www.aphis.usda.gov/animal-health/secd. Accessed 9 November 2014.
23. Pasick J, Berhane Y, Ojkic D, Maxie G, Embury-Hyatt C, Swekla K, Handel K, Fairles J, Alexandersen S. 2014. Investigation into the role of potentially contaminated feed as a source of the first-detected outbreaks of porcine epidemic diarrhea in Canada. Transbound Emerg Dis 61: 397-410. http://dx.doi.org/10.1111/tbed.12269.
24. Opriessnig T, Xiao CT, Gerber PF, Zhang J, Halbur PG. 2014. Porcine epidemic diarrhea virus RNA present in commercial spray-dried porcine plasma is not infectious to naive pigs. PLoS One 9:e104766. http:// dx.doi.org/10.1371/journal.pone.0104766.
25. OIE. 2014. Technical-Facsheet. Infection with porcine epidemic diarrhoea virus. World Organization for Animal Health (OIE), Paris, France. http://www.oie.int/fileadmin/Home/eng/Our_scientific_expertise/docs/ pdf/A_factsheet_PEDV.pdf. Accessed 10 November 2014.
26. Wong AH, Cheng PK, Lai MY, Leung PC, Wong KK, Lee WY, Lim WW. 2012. Virulence potential of fusogenic orthoreoviruses. Emerg Infect Dis 18:944-948. http://dx.doi.org/10.3201/eid1806.111688.
27. Lelli D, Moreno A, Lavazza A, Bresaola M, Canelli E, Boniotti MB, Cordioli P. 2013. Identification of mammalian orthoreovirus type 3 in Italian bats. Zoonoses Public Health 60:84-92. http://dx.doi.org/10.1111/ zph.12001.
28. Chappell JD, Barton ES, Smith TH, Baer GS, Duong DT, Nibert ML, Dermody TS. 1998. Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck. J Virol 72:8205-8213.
29. Bassel-Duby R, Spriggs DR, Tyler KL, Fields BN. 1986. Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique. J Virol 60:64-67.
30. Kaye KM, Spriggs DR, Bassel-Duby R, Fields BN, Tyler KL. 1986. Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing). J Virol 59:90-97.
31. Irvin SC, Zurney J, Ooms LS, Chappell JD, Dermody TS, Sherry B. 2012. A single-amino-acid polymorphism in reovirus protein mu2 determines repression of interferon signaling and modulates myocarditis. J Virol 86:2302-2311. http://dx.doi.org/10.1128/JVI.06236-11.
32. Middleton JK, Agosto MA, Severson TF, Yin J, Nibert ML. 2007. Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles. Virology 361: 412-425. http://dx.doi.org/10.1016/j.virol.2006.11.024.
33. Dermody TS, Nibert ML, Bassel-Duby R, Fields BN. 1990. Sequence diversity in S1 genes and S1 translation products of 11 serotype 3 reovirus strains. J Virol 64:4842-4850.
34. Goral MI, Mochow-Grundy M, Dermody TS. 1996. Sequence diversity within the reovirus S3 gene: reoviruses evolve independently of host species, geographic locale, and date of isolation. Virology 216:265-271. http://dx.doi.org/10.1006/viro.1996.0059.
35. Kedl R, Schmechel S, Schiff L. 1995. Comparative sequence analysis of the reovirus S4 genes from 13 serotype 1 and serotype 3 field isolates. J Virol 69:552-559.
36. Dai Y, Zhou Q, Zhang C, Song Y, Tian X, Zhang X, Xue C, Xu S, Bi Y, Cao Y. 2012. Complete genome sequence of a porcine orthoreovirus from southern China. J Virol 86:12456. http://dx.doi.org/10.1128/JVI.02254-12.
37. Chua KB, Voon K, Crameri G, Tan HS, Rosli J, McEachern JA, Suluraju S, Yu M, Wang LF. 2008. Identification and characterization of a new orthoreovirus from patients with acute respiratory infections. PLoS One 3:e3803. http://dx.doi.org/10.1371/journal.pone.0003803.
38. Kongsted H, Jonach B, Haugegaard S, Angen Ø, Jorsal SE, Kokotovic B, Larsen LE, Jensen TK, Nielsen JP. 2013. Microbiological, pathological and histological findings in four Danish pig herds affected by a new neonatal diarrhoea syndrome.BMCVet Res 9:206. http://dx.doi.org/10.1186/ 1746-6148-9-206.
39. Clarke P, Meintzer SM, Spalding AC, Johnson GL, Tyler KL. 2001. Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection. Oncogene 20:6910-6919. http:// dx.doi.org/10.1038/sj.onc.1204842.
40. Tardieu M, Powers ML, Weiner HL. 1983. Age dependent susceptibility to reovirus type 3 encephalitis: role of viral and host factors. Ann Neurol 13:602-607. http://dx.doi.org/10.1002/ana.410130604.
41. Attoui H, Mohd Jaafar F, de Micco P, de Lamballerie X. 2005. Coltiviruses and seadornaviruses in North America, Europe, and Asia. Emerg Infect Dis 11:1673-1679. http://dx.doi.org/10.3201/eid1111.050868.
42. Huang YW, Dickerman AW, Piñeyro P, Li L, Fang L, Kiehne R, Opriessnig T, Meng XJ. 2013. Origin, evolution, and genotyping of emergent porcine epidemic diarrhea virus strains in the United States. mBio 4(5):e00737-13. http://dx.doi.org/10.1128/mBio.00737-13.
43. Dermody TS, Nibert ML, Bassel-Duby R, Fields BN. 1990. A sigma 1 region important for hemagglutination by serotype 3 reovirus strains. J Virol 64:5173-5176.
44. Conesa A, Gotz S, Garcia-Gomez JM, Terol J, Talon M, Robles M 2005. Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics 21:3674-3676. http:// dx.doi.org/10.1093/bioinformatics/bti610.
45. Jones DT, Taylor WR, Thornton JM. 1992. The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci 8:275-282. http://dx.doi.org/10.1093/bioinformatics/8.3.275.
46. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. 2013. MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30: 2725-2729. http://dx.doi.org/10.1093/molbev/mst197.
47. Jukes TH, Cantor CR. 1969. Evolution of protein molecules, p 21-132. In Munro HM (ed), Mammalian protein metabolism. Academic Press, Waltham, MA.
48. Elazhary MA, Morin M, Derbyshire JB, Lagacé A, Berthiaume L, Corbeil M. 1978. The experimental infection of piglets with a porcine reovirus. Res Vet Sci 25:16-20.