Anti-signal recognition particle autoantibody ELISA validation and clinical associations

Rheumatology (United Kingdom)

Volumn 54, Issue 7, 2015, Pages 1194-1199

  Aggarwal, Rohit ^a   Oddis, Chester V ^a   Goudeau, Danielle ^a   Fertig, Noreen ^a   Metes, Ilinca ^a   Stephens, Chad ^a   Qi, Zengbiao ^a   Koontz, Diane ^a   Levesque, Marc C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Anti signal recognition particle (SRP) autoantibody; ELISA; Idiopathic inflammatory myopathy; Immunoprecipitation; Quantitative measure

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN G; MUSCLE ENZYME; SIGNAL RECOGNITION PARTICLE ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GOLD STANDARD; HUMAN; IMMUNOPRECIPITATION; LONGITUDINAL STUDY; MYOSITIS; PREDICTIVE VALUE; PRIORITY JOURNAL; TEST RETEST RELIABILITY; VALIDATION PROCESS;

EID: 84936849741     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keu436     Document Type: Article

References (18)

1. Bernstein RM, Morgan SH, Chapman J et al. Anti-Jo-1 antibody: a marker for myositis with interstitial lung disease. Br Med J (Clin Res Ed) 1984;289:151-2.
2. Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). N Engl J Med 1975;292:403-7.
3. Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med 1975;292:344-7.
4. Brouwer R, Hengstman GJ, Vree Egberts W et al. Autoantibody profiles in the sera of European patients with myositis. Ann Rheum Dis 2001;60:116-23.
5. Hengstman GJ, ter Laak HJ, Vree Egberts WT et al. Antisignal recognition particle autoantibodies: marker of a necrotising myopathy. Ann Rheum Dis 2006;65:1635-8.
6. Targoff IN, Johnson AE, Miller FW. Antibody to signal recognition particle in polymyositis. Arthritis Rheum 1990; 33:1361-70.
7. Valiyil R, Casciola-Rosen L, Hong G, Mammen A, Christopher-Stine L. Rituximab therapy for myopathy associated with anti-signal recognition particle antibodies: a case series. Arthritis Care Res 2010;62:1328-34.
8. Garcia-Rosell M, Moore S, Pattanaik D et al. Signal recognition antibody-positive myopathy and response to intravenous immunoglobulin G (IVIG). J Clin Rheumatol 2013;19:214-7.
9. Reeves WH, Nigam SK, Blobel G. Human autoantibodies reactive with the signal-recognition particle. Proc Natl Acad Sci U S A 1986;83:9507-11.
10. Okada N, Mimori T, Mukai R, Kashiwagi H, Hardin JA. Characterization of human autoantibodies that selectively precipitate the 7SL RNA component of the signal recognition particle. J Immunol 1987;138: 3219-23.
11. Janda CY, Li J, Oubridge C et al. Recognition of a signal peptide by the signal recognition particle. Nature 2010; 465:507-10.
12. Romisch K, Miller FW, Dobberstein B, High S. Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages. Arthritis Res Ther 2006;8:R39.
13. Benveniste O, Drouot L, Jouen F et al. Correlation of antisignal recognition particle autoantibody levels with creatine kinase activity in patients with necrotizing myopathy. Arthritis Rheum 2011;63:1961-71.
14. Hoogendijk JE, Amato AA, Lecky BR et al. 119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10-12 October 2003, Naarden, The Netherlands. Neuromuscul Disord 2004;14: 337-45.
15. Aggarwal R, Lucas M, Fertig N, Oddis CV, Medsger TA Jr. Anti-U3 RNP autoantibodies in systemic sclerosis. Arthritis Rheum 2009;60:1112-8.
16. Okano Y, Medsger TA Jr. Novel human autoantibodies reactive with 50-terminal trimethylguanosine cap structures of U small nuclear RNA. J Immunol 1992;149: 1093-8.
17. Mitri GM, Lucas M, Fertig N, Steen VD, Medsger TA Jr. A comparison between anti-Th/To-and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement. Arthritis Rheum 2003;48: 203-9.
18. Oddis CV, Reed AM, Aggarwal R et al. Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo-phase trial. Arthritis Rheum 2013;65:314-24.