Quantitative proteomics of human fibroblasts with I1061T mutation in niemann-Pick C1 (NPC1) protein provides insights into the disease pathogenesis

Molecular and Cellular Proteomics

Volumn 14, Issue 7, 2015, Pages 1734-1749

  Rauniyar, Navin ^a   Subramanian, Kanagaraj ^a   Lavallée Adam, Mathieu ^a   Martínez Bartolomé, Salvador ^a   Balch, William E ^a   Yates, John R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORDC1 PROTEIN; CLGN PROTEIN; DHCR24 PROTEIN; GAA PROTEIN; GLUCAN 1,4 ALPHA GLUCOSIDASE; GLYCOGEN; HSPB7 PROTEIN; LIPID; NPC1 PROTEIN; PROTEIN; PROTEOME; REACTIVE OXYGEN METABOLITE; SOD2 PROTEIN; TOR4A PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; MEMBRANE PROTEIN; NPC1 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DATA ANALYSIS; DOWN REGULATION; ENERGY METABOLISM; FIBROBLAST; GENE MUTATION; GENE ONTOLOGY; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NIEMANN PICK DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEOMICS; QUANTITATIVE ANALYSIS; STEROID METABOLISM; UPREGULATION; WESTERN BLOTTING; WILD TYPE; WORKFLOW; GENETICS; ISOTOPE LABELING; METABOLISM; MOLECULAR WEIGHT; MUTATION; PATHOLOGY; PROCEDURES; PROTEIN DATABASE; REPRODUCIBILITY;

BLOTTING, WESTERN; CARRIER PROTEINS; DATABASES, PROTEIN; DOWN-REGULATION; FIBROBLASTS; GENE ONTOLOGY; HUMANS; ISOTOPE LABELING; MEMBRANE GLYCOPROTEINS; MOLECULAR WEIGHT; MUTATION; NIEMANN-PICK DISEASE, TYPE C; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SUPEROXIDE DISMUTASE;

EID: 84936797105     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M114.045609     Document Type: Article

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