Doxorubicin Induces Sarcoplasmic Reticulum Calcium Regulation Dysfunction via the Decrease of SERCA2 and Phospholamban Expressions in Rats

Cell Biochemistry and Biophysics

Volumn 70, Issue 3, 2014, Pages 1791-1798

  Zhang, Yachen ^a   Chen, Yu ^a   Zhang, Min ^a   Tang, Yong ^a   Xie, Yuquan ^a   Huang, Xiaohong ^a   Li, Yigang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Doxorubicin; Phospholamban; Sarcoplasmic reticulum calcium regulation dysfunction; SERCA2

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; ATP2A2 PROTEIN, RAT; CALCIUM; CALCIUM BINDING PROTEIN; DOXORUBICIN; MALONALDEHYDE; NITRIC OXIDE; OXIDOREDUCTASE; PHOSPHOLAMBAN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL; BLOOD; CARDIOMYOPATHY; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; HEART VENTRICLE; HEMODYNAMICS; MALE; METABOLISM; ORGAN SIZE; OXIDATIVE STRESS; PATHOLOGY; RAT; SARCOPLASMIC RETICULUM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CALCIUM; CALCIUM-BINDING PROTEINS; CARDIOMYOPATHIES; DOXORUBICIN; GENE EXPRESSION REGULATION; HEART VENTRICLES; HEMODYNAMICS; MALE; MALONDIALDEHYDE; NITRIC OXIDE; ORGAN SIZE; OXIDATIVE STRESS; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 84936760000     PISSN: 10859195     EISSN: 15590283     Source Type: Journal    
DOI: 10.1007/s12013-014-0130-2     Document Type: Article

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