Extrahepatic sources of factor VIII potentially contribute to the coagulation cascade correcting the bleeding phenotype of mice with hemophilia A

Haematologica

Volumn 100, Issue 7, 2015, Pages 881-892

  Zanolini, Diego ^a   Merlin, Simone ^a   Feola, Maria ^a   Ranaldo, Gabriella ^a   Amoruso, Angela ^a   Gaidano, Gianluca ^a   Zaffaroni, Mauro ^b   Ferrero, Alessandro ^c   Brunelleschi, Sandra ^a   Valente, Guido ^a   Gupta, Sanjeev ^d   Prat, Maria ^a   Follenzi, Antonia ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b Azienda Ospedaliera Universitaria Maggiore Della Carita   (Italy)

^c MAURIZIANO HOSPITAL   (Italy)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; CD11B ANTIGEN; CD14 ANTIGEN; MESSENGER RNA; VON WILLEBRAND FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING; BLOOD CLOTTING; CELL DIFFERENTIATION; CELL TRANSPLANTATION; CONTROLLED STUDY; CYTOFLUOROMETRY; ENGRAFTMENT; FLUORESCENCE ACTIVATED CELL SORTING; HEMOPHILIA A; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER BIOPSY; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PHASE CONTRAST MICROSCOPY; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOLOGY; DISEASE MODEL; ENDOTHELIUM CELL; FETUS BLOOD; GENE EXPRESSION REGULATION; GENETICS; GRAFT SURVIVAL; HEMORRHAGE; KUPFFER CELL; LIVER; LIVER CELL; MEGAKARYOCYTE; METABOLISM; MONOCYTE; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHENOTYPE; SCID MOUSE; SECRETION (PROCESS); XENOGRAFT;

ANIMALS; BLOOD COAGULATION; CORD BLOOD STEM CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FACTOR VIII; FETAL BLOOD; GENE EXPRESSION REGULATION; GRAFT SURVIVAL; HEMOPHILIA A; HEMORRHAGE; HEPATOCYTES; HUMANS; KUPFFER CELLS; LIVER; MEGAKARYOCYTES; MICE; MICE, INBRED NOD; MICE, SCID; MONOCYTES; PHENOTYPE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84936096796     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2014.123117     Document Type: Article

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