Antiviral effects of Phyllanthus urinaria containing corilagin against human enterovirus 71 and Coxsackievirus A16 in vitro

Archives of Pharmacal Research

Volumn 38, Issue 2, 2015, Pages 193-202

  Yeo, Sang Gu ^b,c   Song, Jae Hyoung ^a,b   Hong, Eun Hye ^a   Lee, Bo Ra ^a   Kwon, Yong Soo ^a   Chang, Sun Young ^d   Kim, Seung Hyun ^e   Lee, Sang Won ^b   Park, Jae Hak ^c   Ko, Hyun Jeong ^a  

^a Kangwon National University   (South Korea)

^b Korea National Institute of Health   (South Korea)

^c Seoul National University   (South Korea)

^d Ajou University   (South Korea)

^e Yonsei University   (South Korea)

Author keywords

Antiviral drug; Corilagin; Coxsackievirus A16; Hand foot and mouth disease; Human enterovirus 71; Phyllanthus urinaria

Indexed keywords

ANTIVIRUS AGENT; CORILAGIN; GLUCOSIDE; PLANT EXTRACT; TANNIN;

ANIMAL; CELL SURVIVAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; CYTOPATHOGENIC EFFECT; DOSE RESPONSE; DRUG EFFECTS; ENTEROVIRUS A; EPITHELIUM CELL; ISOLATION AND PURIFICATION; PATHOGENICITY; PATHOLOGY; PHYLLANTHUS; PLANT; VERO CELL LINE; VIROLOGY;

ANIMALS; ANTIVIRAL AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CYTOPATHOGENIC EFFECT, VIRAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROVIRUS A, HUMAN; EPITHELIAL CELLS; GLUCOSIDES; HYDROLYZABLE TANNINS; PHYLLANTHUS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; VERO CELLS;

EID: 84935908663     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-014-0390-9     Document Type: Article

References (30)

1. Chen, Y., and C. Chen. 2011. Corilagin prevents tert-butyl hydroperoxide-induced oxidative stress injury in cultured n9 murine microglia cells. Neurochemistry International 59(2): 290-296.
2. Cheng, A., C.P. Fung, C.C. Liu, Y.T. Lin, H.Y. Tsai, S.C. Chang, A.H. Chou, J.Y. Chang, R.H. Jiang, Y.C. Hsieh, I.J. Su, et al. 2013. A phase I, randomized, open-label study to evaluate the safety and immunogenicity of an enterovirus 71 vaccine. Vaccine 31(20): 2471-2476.
3. Choi, H.J., J.H. Kim, C.H. Lee, Y.J. Ahn, J.H. Song, S.H. Baek, and D.H. Kwon. 2009a. Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus. Antiviral Research 81(1): 77-81.
4. Choi, H.J., J.H. Song, K.S. Park, and D.H. Kwon. 2009b. Inhibitory effects of quercetin 3-rhamnoside on influenza a virus replication. European Journal of Pharmaceutical Sciences 37(3-4): 329-333.
5. Duan, W., Y. Yu, and L. Zhang. 2005. Antiatherogenic effects of Phyllanthus emblica associated with corilagin and its analogue. Yakugaku Zasshi 125(7): 587-591.
6. Guo, Y.J., L. Zhao, X.F. Li, Y.W. Mei, S.L. Zhang, J.Y. Tao, Y. Zhou, and J.H. Dong. 2010. Effect of corilagin on anti-inflammation in HSV-1 encephalitis and HSV-1 infected microglias. European Journal of Pharmacology 635(1-3): 79-86.
7. Hau, D.K., G.Y. Zhu, A.K. Leung, R.S. Wong, G.Y. Cheng, P.B. Lai, S.W. Tong, F.Y. Lau, K.W. Chan, W.Y. Wong, K.H. Lam, et al. 2010. In vivo anti-tumour activity of corilagin on hep3b hepatocellular carcinoma. Phytomedicine 18(1): 11-15.
8. Jikai, L., H. Yue, T. Henkel, and K. Weber. 2002. One step purification of corilagin and ellagic acid from Phyllanthus urinaria using high-speed countercurrent chromatography. Phytochemical Analysis 13(1): 1-3.
9. Kinoshita, S., Y. Inoue, S. Nakama, T. Ichiba, and Y. Aniya. 2007. Antioxidant and hepatoprotective actions of medicinal herb, terminalia catappa L. From okinawa island and its tannin corilagin. Phytomedicine 14(11): 755-762.
10. Li, Y., S. Yu, D. Liu, P. Proksch, and W. Lin. 2012. Inhibitory effects of polyphenols toward HCV from the mangrove plant excoecaria agallocha L. Bioorganic Medicinal Chemistry Letters 22(2): 1099-1102.
11. Lin, S.Y., C.C. Wang, Y.L. Lu, W.C. Wu, and W.C. Hou. 2008. Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria. Food and Chemical Toxicology 46(7): 2485-2492.
12. Lin, L.T., T.Y. Chen, C.Y. Chung, R.S. Noyce, T.B. Grindley, C. McCormick, T.C. Lin, G.H. Wang, C.C. Lin, and C.D. Richardson. 2011. Hydrolyzable tannins (chebulagic acid and punicalagin) target viral glycoprotein-glycosaminoglycan interactions to inhibit herpes simplex virus 1 entry and cell-to-cell spread. Journal of Virology 85(9): 4386-4398.
13. Lin, L.T., T.Y. Chen, S.C. Lin, C.Y. Chung, T.C. Lin, G.H. Wang, R. Anderson, C.C. Lin, and C.D. Richardson. 2013. Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry. BMC Microbiology 13: 187.
14. Liu, K.C., M.T. Lin, S.S. Lee, J.F. Chiou, S. Ren, and E.J. Lien. 1999. Antiviral tannins from two phyllanthus species. Planta Medica 65(1): 43-46.
15. Mao, Q., Wang, Y., Yao, X., Bian, L., Wu, X., Xu, M., Liang, Z. 2013. Coxsackievirus a16: epidemiology, diagnosis, and vaccine. Human Vaccines Immunotherapeutics 10(2): 360-367.
16. Moreira, J., L.C. Klein-Junior, V. Cechinel Filho, and F. de Campos Buzzi. 2013. Anti-hyperalgesic activity of corilagin, a tannin isolated from Phyllanthus niruri L. (euphorbiaceae). Journal of Ethnopharmacology 146(1): 318-323.
17. Notka, F., G. Meier, and R. Wagner. 2004. Concerted inhibitory activities of Phyllanthus amarus on HIV replication in vitro and ex vivo. Antiviral Research 64(2): 93-102.
18. Park, J.H., H.S. Joo, K.Y. Yoo, B.N. Shin, I.H. Kim, C.H. Lee, J.H. Choi, K. Byun, B. Lee, S.S. Lim, M.J. Kim, et al. 2011. Extract from terminalia chebula seeds protect against experimental ischemic neuronal damage via maintaining SODs and BDNF levels. Neurochemical Research 36(11): 2043-2050.
19. Patel, J.R., P. Tripathi, V. Sharma, N.S. Chauhan, and V.K. Dixit. 2011. Phyllanthus amarus: ethnomedicinal uses, phytochemistry and pharmacology: a review. Journal of Ethnopharmacology 138(2): 286-313.
20. Satomi, H., K. Umemura, A. Ueno, T. Hatano, T. Okuda, and T. Noro. 1993. Carbonic anhydrase inhibitors from the pericarps of punica granatum L. Biological Pharmaceutical Bulletin 16(8): 787-790.
21. Shiota, S., M. Shimizu, J. Sugiyama, Y. Morita, T. Mizushima, and T. Tsuchiya. 2004. Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant staphylococcus aureus. Microbiology and Immunology 48(1): 67-73.
22. Solomon, T., P. Lewthwaite, D. Perera, M.J. Cardosa, P. McMinn, and M.H. Ooi. 2010. Virology, epidemiology, pathogenesis, and control of enterovirus 71. The Lancet Infectious Diseases 10(11): 778-790.
23. Tan, C.W., Y.F. Chan, K.M. Sim, E.L. Tan, and C.L. Poh. 2012. Inhibition of enterovirus 71 (ev-71) infections by a novel antiviral peptide derived from EV-71 capsid protein vp1. PLoS One 7(5): e34589.
24. Thitilertdecha, N., A. Teerawutgulrag, J.D. Kilburn, and N. Rakariyatham. 2010. Identification of major phenolic compounds from nephelium lappaceum 1. And their antioxidant activities. Molecules (Basel, Switzerland) 15(3): 1453-1465.
25. Yang, Y., J. Xiu, L. Zhang, C. Qin, and J. Liu. 2012a. Antiviral activity of punicalagin toward human enterovirus 71 in vitro and in vivo. Phytomedicine 20(1): 67-70.
26. Yang, Y., L. Zhang, X. Fan, C. Qin, and J. Liu. 2012b. Antiviral effect of geraniin on human enterovirus 71 in vitro and in vivo. Bioorganic Medicinal Chemistry Letters 22(6): 2209-2211.
27. Yang, Y., J. Xiu, J. Liu, L. Zhang, X. Li, Y. Xu, and C. Qin. 2013. Chebulagic acid, a hydrolysable tannin, exhibited antiviral activity in vitro and in vivo against human enterovirus 71. International Journal of Molecular Sciences 14(5): 9618-9627.
28. Yuandani, M. Ilangkovan, I. Jantan, H.F. Mohamad, K. Husain, and A.F. Abdul Razak. 2013. Inhibitory effects of standardized extracts of Phyllanthus amarus and Phyllanthus urinaria and their marker compounds on phagocytic activity of human neutrophils. Evidence-Based Complementary and Alternative Medicine 2013: 603634. doi: 10.1155/2013/603634
29. Zhao, L., S.L. Zhang, J.Y. Tao, R. Pang, F. Jin, Y.J. Guo, J.H. Dong, P. Ye, H.Y. Zhao, and G.H. Zheng. 2008. Preliminary exploration on anti-inflammatory mechanism of corilagin (beta-1-o-galloyl-3,6-(r)-hexahydroxydiphenoyl-d-glucose) in vitro. International Immunopharmacology 8(7): 1059-1064.
30. Zheng, Z., H. Li, Z. Zhang, J. Meng, D. Mao, B. Bai, B. Lu, P. Mao, Q. Hu, and H. Wang. 2011. Enterovirus 71 2c protein inhibits tnf-alpha-mediated activation of nf-kappab by suppressing ikappab kinase beta phosphorylation. Journal of immunology (Baltimore, Md: 1950) 187(5): 2202-2212.