Cyclin-dependent kinase 5 regulates the proliferation, motility and invasiveness of lung cancer cells through its effects on cytoskeletal remodeling

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 3979-3985

  Liu, Jun Li ^a   Gu, Run Xia ^a   Zhou, Xiao Shu ^a   Zhou, Fang Zheng ^b   Wu, Gang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Dept of Cardiology   (China)

Author keywords

Cyclin dependent kinase 5; Invasiveness; Lung cancer; Motility; Roscovitine; Small interfering RNA

Indexed keywords

CYCLIN DEPENDENT KINASE 5; ROSCOVITINE; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; CDK5 PROTEIN, HUMAN; PURINE DERIVATIVE;

A549 CELL LINE; ANIMAL EXPERIMENT; ARTICLE; CELL INVASION; CELL MOTILITY; CELL POLARITY; CELL PROLIFERATION; CELL STRUCTURE; CYTOSKELETON; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL MOTION; DRUG EFFECTS; FEMALE; GENETICS; LUNG TUMOR; METABOLISM; MICROVILLUS; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 5; CYTOSKELETON; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROVILLI; PURINES; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84935447593     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3868     Document Type: Article

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