Amino acids of importance for the antioxidant activity of human serum albumin as revealed by recombinant mutants and genetic variants

Life Sciences

Volumn 134, Issue 1, 2015, Pages 36-41

  Anraku, Makoto ^a   Shintomo, Rina ^b   Taguchi, Kazuaki ^a   Kragh Hansen, Ulrich ^c   Kai, Toshiya ^d   Maruyama, Toru ^b   Otagiri, Masaki ^a  

^a SOJO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c AARHUS UNIVERSITY   (Denmark)

^d Nipro Corporation   (Japan)

Author keywords

Antioxidant; Cysteine 34; Genetic variants; Human serum albumin; Methionine; Recombinant mutants

Indexed keywords

AMINO ACID; ANTIOXIDANT; CYSTEINE; DIHYDRORHODAMINE 123; GLUTAMIC ACID; HUMAN SERUM ALBUMIN; HYDROGEN PEROXIDE; METHIONINE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; RECOMBINANT PROTEIN; RHODAMINE; SERUM ALBUMIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIOXIDANT ACTIVITY; ARTICLE; CIRCULAR DICHROISM; DISULFIDE BOND; GENETIC VARIABILITY; HETEROZYGOTE; MUTANT; NONHUMAN; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN FUNCTION; CHEMISTRY; GENETICS; HUMAN; MISSENSE MUTATION; OXIDATION REDUCTION REACTION; SPECTROFLUOROMETRY;

AMINO ACID SUBSTITUTION; HUMANS; HYDROGEN PEROXIDE; MUTATION, MISSENSE; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; RHODAMINES; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE;

EID: 84935008595     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.05.010     Document Type: Article

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